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Results: 1 to 20 of 26

1.

Knock-In Reporter Mice Demonstrate that DNA Repair by Non-homologous End Joining Declines with Age.

Vaidya A, Mao Z, Tian X, Spencer B, Seluanov A, Gorbunova V.

PLoS Genet. 2014 Jul 17;10(7):e1004511. doi: 10.1371/journal.pgen.1004511. eCollection 2014 Jul.

PMID:
25033455
[PubMed - in process]
Free PMC Article
2.

Immunosenescence is associated with altered gene expression and epigenetic regulation in primary and secondary immune organs.

Sidler C, Wóycicki R, Ilnytskyy Y, Metz G, Kovalchuk I, Kovalchuk O.

Front Genet. 2013 Oct 18;4:211. doi: 10.3389/fgene.2013.00211. eCollection 2013.

PMID:
24151501
[PubMed]
Free PMC Article
3.

Human APOBEC3A isoforms translocate to the nucleus and induce DNA double strand breaks leading to cell stress and death.

Mussil B, Suspène R, Aynaud MM, Gauvrit A, Vartanian JP, Wain-Hobson S.

PLoS One. 2013 Aug 20;8(8):e73641. doi: 10.1371/journal.pone.0073641. eCollection 2013.

PMID:
23977391
[PubMed - in process]
Free PMC Article
4.

Metabolism, longevity and epigenetics.

Cosentino C, Mostoslavsky R.

Cell Mol Life Sci. 2013 May;70(9):1525-41. doi: 10.1007/s00018-013-1295-3. Epub 2013 Mar 7. Review.

PMID:
23467663
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Coordination of DNA repair by NEIL1 and PARP-1: a possible link to aging.

Noren Hooten N, Fitzpatrick M, Kompaniez K, Jacob KD, Moore BR, Nagle J, Barnes J, Lohani A, Evans MK.

Aging (Albany NY). 2012 Oct;4(10):674-85.

PMID:
23104860
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Pancreatic beta cells in very old mice retain capacity for compensatory proliferation.

Stolovich-Rain M, Hija A, Grimsby J, Glaser B, Dor Y.

J Biol Chem. 2012 Aug 10;287(33):27407-14. doi: 10.1074/jbc.M112.350736. Epub 2012 Jun 27.

PMID:
22740691
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

DNA MMR systems, microsatellite instability and antioxidant activity variations in two species of wild bats: Myotis velifer and Desmodus rotundus, as possible factors associated with longevity.

Conde-Pérezprina JC, Luna-López A, González-Puertos VY, Zenteno-Savín T, León-Galván MA, Königsberg M.

Age (Dordr). 2012 Dec;34(6):1473-92. doi: 10.1007/s11357-012-9399-5. Epub 2012 Mar 28.

PMID:
22453932
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Glutamine acts as a neuroprotectant against DNA damage, beta-amyloid and H2O2-induced stress.

Chen J, Herrup K.

PLoS One. 2012;7(3):e33177. doi: 10.1371/journal.pone.0033177. Epub 2012 Mar 8.

PMID:
22413000
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Measuring genome instability in aging - a mini-review.

Li W, Vijg J.

Gerontology. 2012;58(2):129-38. doi: 10.1159/000334368. Epub 2011 Dec 10. Review.

PMID:
22156741
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Instability of the octarepeat region of the human prion protein gene.

Li B, Qing L, Yan J, Kong Q.

PLoS One. 2011;6(10):e26635. doi: 10.1371/journal.pone.0026635. Epub 2011 Oct 19.

PMID:
22028931
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

The genome as a life-history character: why rate of molecular evolution varies between mammal species.

Bromham L.

Philos Trans R Soc Lond B Biol Sci. 2011 Sep 12;366(1577):2503-13. doi: 10.1098/rstb.2011.0014. Review.

PMID:
21807731
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Single-nucleotide polymorphisms in DNA repair genes and association with breast cancer risk in the web study.

Roberts MR, Shields PG, Ambrosone CB, Nie J, Marian C, Krishnan SS, Goerlitz DS, Modali R, Seddon M, Lehman T, Amend KL, Trevisan M, Edge SB, Freudenheim JL.

Carcinogenesis. 2011 Aug;32(8):1223-30. doi: 10.1093/carcin/bgr096. Epub 2011 May 27.

PMID:
21622940
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Aging mice have increased chromosome instability that is exacerbated by elevated Mdm2 expression.

Lushnikova T, Bouska A, Odvody J, Dupont WD, Eischen CM.

Oncogene. 2011 Nov 17;30(46):4622-31. doi: 10.1038/onc.2011.172. Epub 2011 May 23.

PMID:
21602883
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

To live or to die: a matter of processing damaged DNA termini in neurons.

El-Khamisy SF.

EMBO Mol Med. 2011 Feb;3(2):78-88. doi: 10.1002/emmm.201000114. Epub 2011 Jan 19. Review.

PMID:
21246735
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

DNA-SCARS: distinct nuclear structures that sustain damage-induced senescence growth arrest and inflammatory cytokine secretion.

Rodier F, Muñoz DP, Teachenor R, Chu V, Le O, Bhaumik D, Coppé JP, Campeau E, Beauséjour CM, Kim SH, Davalos AR, Campisi J.

J Cell Sci. 2011 Jan 1;124(Pt 1):68-81. doi: 10.1242/jcs.071340. Epub 2010 Nov 30.

PMID:
21118958
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Microsatellite instability in Arabidopsis increases with plant development.

Golubov A, Yao Y, Maheshwari P, Bilichak A, Boyko A, Belzile F, Kovalchuk I.

Plant Physiol. 2010 Nov;154(3):1415-27. doi: 10.1104/pp.110.162933. Epub 2010 Sep 3.

PMID:
20817752
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Recruitment of Rad51 and Rad52 to short telomeres triggers a Mec1-mediated hypersensitivity to double-stranded DNA breaks in senescent budding yeast.

Lin YH, Chang CC, Wong CW, Teng SC.

PLoS One. 2009 Dec 14;4(12):e8224. doi: 10.1371/journal.pone.0008224.

PMID:
20011546
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

GIN'n'CIN hypothesis of brain aging: deciphering the role of somatic genetic instabilities and neural aneuploidy during ontogeny.

Yurov YB, Vorsanova SG, Iourov IY.

Mol Cytogenet. 2009 Nov 25;2:23. doi: 10.1186/1755-8166-2-23.

PMID:
19939257
[PubMed]
Free PMC Article
19.

Checkpoint kinase phosphorylation in response to endogenous oxidative DNA damage in repair-deficient stationary-phase Saccharomyces cerevisiae.

Pawar V, Jingjing L, Patel N, Kaur N, Doetsch PW, Shadel GS, Zhang H, Siede W.

Mech Ageing Dev. 2009 Aug;130(8):501-8. doi: 10.1016/j.mad.2009.06.002. Epub 2009 Jun 18.

PMID:
19540258
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

XRCC2 and XRCC3 regulate the balance between short- and long-tract gene conversions between sister chromatids.

Nagaraju G, Hartlerode A, Kwok A, Chandramouly G, Scully R.

Mol Cell Biol. 2009 Aug;29(15):4283-94. doi: 10.1128/MCB.01406-08. Epub 2009 May 26.

PMID:
19470754
[PubMed - indexed for MEDLINE]
Free PMC Article

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