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Results: 1 to 20 of 31

1.

Data-driven identification of structural alerts for mitigating the risk of drug-induced human liver injuries.

Liu R, Yu X, Wallqvist A.

J Cheminform. 2015 Feb 11;7:4. doi: 10.1186/s13321-015-0053-y. eCollection 2015.

PMID:
25717346
[PubMed]
Free Article
2.

Glycyrrhetinic acid and E.resveratroloside act as potential plant derived compounds against dopamine receptor D3 for Parkinson's disease: a pharmacoinformatics study.

Mirza MU, Mirza AH, Ghori NU, Ferdous S.

Drug Des Devel Ther. 2014 Dec 18;9:187-98. doi: 10.2147/DDDT.S72794. eCollection 2015.

PMID:
25565772
[PubMed - in process]
Free PMC Article
3.

Cytochrome P450 induction properties of food and herbal-derived compounds using a novel multiplex RT-qPCR in vitro assay, a drug-food interaction prediction tool.

Koe XF, Tengku Muhammad TS, Chong AS, Wahab HA, Tan ML.

Food Sci Nutr. 2014 Sep;2(5):500-20. doi: 10.1002/fsn3.122. Epub 2014 Jun 10.

PMID:
25473508
[PubMed]
Free PMC Article
4.

A Novel CMKLR1 Small Molecule Antagonist Suppresses CNS Autoimmune Inflammatory Disease.

Graham KL, Zhang JV, Lewén S, Burke TM, Dang T, Zoudilova M, Sobel RA, Butcher EC, Zabel BA.

PLoS One. 2014 Dec 1;9(12):e112925. doi: 10.1371/journal.pone.0112925. eCollection 2014.

PMID:
25437209
[PubMed - in process]
Free PMC Article
5.

Cytochrome P450 single nucleotide polymorphisms in an indigenous Tanzanian population: a concern about the metabolism of artemisinin-based combinations.

Marwa KJ, Schmidt T, Sjögren M, Minzi OM, Kamugisha E, Swedberg G.

Malar J. 2014 Nov 3;13:420. doi: 10.1186/1475-2875-13-420.

PMID:
25363545
[PubMed - in process]
Free PMC Article
6.

Inhibition of Human Cytochrome P450 Enzymes by Allergen Removed Rhus verniciflua Stoke Standardized Extract and Constituents.

Jung H, Lee S.

Evid Based Complement Alternat Med. 2014;2014:150351. doi: 10.1155/2014/150351. Epub 2014 Jun 30.

PMID:
25061471
[PubMed]
Free PMC Article
7.

Analysis of single-nucleotide polymorphisms (SNPs) in human CYP3A4 and CYP3A5 genes: potential implications for the metabolism of HIV drugs.

Berno G, Zaccarelli M, Gori C, Tempestilli M, Antinori A, Perno CF, Pucillo LP, D'Arrigo R.

BMC Med Genet. 2014 Jul 2;15:76. doi: 10.1186/1471-2350-15-76.

PMID:
24986243
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Inhibitors of the glyoxylate cycle enzyme ICL1 in Candida albicans for potential use as antifungal agents.

Cheah HL, Lim V, Sandai D.

PLoS One. 2014 Apr 29;9(4):e95951. doi: 10.1371/journal.pone.0095951. eCollection 2014.

PMID:
24781056
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

QSAR and docking studies on xanthone derivatives for anticancer activity targeting DNA topoisomerase IIα.

Alam S, Khan F.

Drug Des Devel Ther. 2014 Jan 31;8:183-95. doi: 10.2147/DDDT.S51577. eCollection 2014.

PMID:
24516330
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

African variation at Cytochrome P450 genes: Evolutionary aspects and the implications for the treatment of infectious diseases.

Bains RK.

Evol Med Public Health. 2013 Jan;2013(1):118-34. doi: 10.1093/emph/eot010. Epub 2013 May 15.

PMID:
24481193
[PubMed]
Free PMC Article
11.

A quick review of carbamazepine pharmacokinetics in epilepsy from 1953 to 2012.

Tolou-Ghamari Z, Zare M, Habibabadi JM, Najafi MR.

J Res Med Sci. 2013 Mar;18(Suppl 1):S81-5.

PMID:
23961295
[PubMed]
Free PMC Article
12.

Preliminarily Analysis of Carbamazepine (CBZ) C0 in Patients Visited Isfahan Epileptic Clinics.

Tolou-Ghamari Z, Najafi MR, Habibabadi JM, Zare M.

Int J Prev Med. 2013 May;4(Suppl 2):S343-6.

PMID:
23776749
[PubMed]
Free PMC Article
13.

A sensitive and specific CYP cocktail assay for the simultaneous assessment of human cytochrome P450 activities in primary cultures of human hepatocytes using LC-MS/MS.

Pillai VC, Strom SC, Caritis SN, Venkataramanan R.

J Pharm Biomed Anal. 2013 Feb 23;74:126-32. doi: 10.1016/j.jpba.2012.10.016. Epub 2012 Oct 22.

PMID:
23245243
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Clinical pharmacology in sleep medicine.

Proctor A, Bianchi MT.

ISRN Pharmacol. 2012;2012:914168. doi: 10.5402/2012/914168. Epub 2012 Nov 14.

PMID:
23213564
[PubMed]
Free PMC Article
15.

Pharmacogenomics in clinical practice and drug development.

Harper AR, Topol EJ.

Nat Biotechnol. 2012 Nov;30(11):1117-24. doi: 10.1038/nbt.2424. Epub 2012 Nov 8. Review. Erratum in: Nat Biotechnol. 2012 Dec;30(12):1249.

PMID:
23138311
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Molecular mechanisms underlying chemical liver injury.

Gu X, Manautou JE.

Expert Rev Mol Med. 2012 Feb 3;14:e4. doi: 10.1017/S1462399411002110. Review.

PMID:
22306029
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Active-site hydration and water diffusion in cytochrome P450cam: a highly dynamic process.

Miao Y, Baudry J.

Biophys J. 2011 Sep 21;101(6):1493-503. doi: 10.1016/j.bpj.2011.08.020. Epub 2011 Sep 20.

PMID:
21943431
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Selective reduction of methylsulfinyl-containing compounds by mammalian MsrA suggests a strategy for improved drug efficacy.

Lee BC, Fomenko DE, Gladyshev VN.

ACS Chem Biol. 2011 Oct 21;6(10):1029-35. doi: 10.1021/cb2001395. Epub 2011 Aug 22.

PMID:
21823615
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Pharmacokinetics and pharmacodynamics following maintenance doses of prasugrel and clopidogrel in Chinese carriers of CYP2C19 variants.

Kelly RP, Close SL, Farid NA, Winters KJ, Shen L, Natanegara F, Jakubowski JA, Ho M, Walker JR, Small DS.

Br J Clin Pharmacol. 2012 Jan;73(1):93-105. doi: 10.1111/j.1365-2125.2011.04049.x.

PMID:
21689142
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Advances in structure elucidation of small molecules using mass spectrometry.

Kind T, Fiehn O.

Bioanal Rev. 2010 Dec;2(1-4):23-60. Epub 2010 Aug 21.

PMID:
21289855
[PubMed]
Free PMC Article
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