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Items: 1 to 20 of 101

1.

Increased extrasynaptic GluN2B expression is involved in cognitive impairment after isoflurane anesthesia.

Li L, Li Z, Cao Y, Fan D, Chui D, Guo X.

Exp Ther Med. 2016 Jul;12(1):161-168. Epub 2016 Apr 28.

2.

Mutations in CAPN1 Cause Autosomal-Recessive Hereditary Spastic Paraplegia.

Gan-Or Z, Bouslam N, Birouk N, Lissouba A, Chambers DB, Vérièpe J, Androschuck A, Laurent SB, Rochefort D, Spiegelman D, Dionne-Laporte A, Szuto A, Liao M, Figlewicz DA, Bouhouche A, Benomar A, Yahyaoui M, Ouazzani R, Yoon G, Dupré N, Suchowersky O, Bolduc FV, Parker JA, Dion PA, Drapeau P, Rouleau GA, Bencheikh BO.

Am J Hum Genet. 2016 May 5;98(5):1038-46. doi: 10.1016/j.ajhg.2016.04.002.

PMID:
27153400
3.

Involvement of aberrant cyclin-dependent kinase 5/p25 activity in experimental traumatic brain injury.

Yousuf MA, Tan C, Torres-Altoro MI, Lu FM, Plautz E, Zhang S, Takahashi M, Hernandez A, Kernie SG, Plattner F, Bibb JA.

J Neurochem. 2016 Jul;138(2):317-27. doi: 10.1111/jnc.13620. Epub 2016 May 25.

PMID:
26998748
4.

Cdk5-FOXO3a axis: initially neuroprotective, eventually neurodegenerative in Alzheimer's disease models.

Shi C, Viccaro K, Lee HG, Shah K.

J Cell Sci. 2016 Mar 9. pii: jcs.185009. [Epub ahead of print]

PMID:
26962010
5.

Status Epilepticus Enhances Depotentiation after Fully Established LTP in an NMDAR-Dependent but GluN2B-Independent Manner.

Guli X, Tokay T, Kirschstein T, Köhling R.

Neural Plast. 2016;2016:6592038. doi: 10.1155/2016/6592038. Epub 2016 Jan 3.

6.

Calpain-1 and Calpain-2: The Yin and Yang of Synaptic Plasticity and Neurodegeneration.

Baudry M, Bi X.

Trends Neurosci. 2016 Apr;39(4):235-45. doi: 10.1016/j.tins.2016.01.007. Epub 2016 Feb 10. Review.

PMID:
26874794
7.

The Ever-Changing Morphology of Hippocampal Granule Neurons in Physiology and Pathology.

Llorens-Martín M, Rábano A, Ávila J.

Front Neurosci. 2016 Jan 19;9:526. doi: 10.3389/fnins.2015.00526. eCollection 2015.

8.

Phosphorylation of CRMP2 by Cdk5 Regulates Dendritic Spine Development of Cortical Neuron in the Mouse Hippocampus.

Jin X, Sasamoto K, Nagai J, Yamazaki Y, Saito K, Goshima Y, Inoue T, Ohshima T.

Neural Plast. 2016;2016:6790743. doi: 10.1155/2016/6790743. Epub 2015 Dec 27.

9.

Inhibition of endothelial Cdk5 reduces tumor growth by promoting non-productive angiogenesis.

Merk H, Zhang S, Lehr T, Müller C, Ulrich M, Bibb JA, Adams RH, Bracher F, Zahler S, Vollmar AM, Liebl J.

Oncotarget. 2016 Feb 2;7(5):6088-104. doi: 10.18632/oncotarget.6842.

10.

Effects of p35 Mutations Associated with Mental Retardation on the Cellular Function of p35-CDK5.

Takada S, Mizuno K, Saito T, Asada A, Giese KP, Hisanaga S.

PLoS One. 2015 Oct 15;10(10):e0140821. doi: 10.1371/journal.pone.0140821. eCollection 2015.

11.

Cyclin-dependent kinase 5 represses Foxp3 gene expression and Treg development through specific phosphorylation of Stat3 at Serine 727.

Lam E, Choi SH, Pareek TK, Kim BG, Letterio JJ.

Mol Immunol. 2015 Oct;67(2 Pt B):317-24. doi: 10.1016/j.molimm.2015.06.015. Epub 2015 Jul 19.

PMID:
26198700
12.

The role of ventral striatal cAMP signaling in stress-induced behaviors.

Plattner F, Hayashi K, Hernández A, Benavides DR, Tassin TC, Tan C, Day J, Fina MW, Yuen EY, Yan Z, Goldberg MS, Nairn AC, Greengard P, Nestler EJ, Taussig R, Nishi A, Houslay MD, Bibb JA.

Nat Neurosci. 2015 Aug;18(8):1094-100. doi: 10.1038/nn.4066. Epub 2015 Jul 20.

13.

CDK5 knockdown prevents hippocampal degeneration and cognitive dysfunction produced by cerebral ischemia.

Gutiérrez-Vargas JA, Múnera A, Cardona-Gómez GP.

J Cereb Blood Flow Metab. 2015 Dec;35(12):1937-49. doi: 10.1038/jcbfm.2015.150. Epub 2015 Jun 24.

PMID:
26104286
14.

Cdk5 is a New Rapid Synaptic Homeostasis Regulator Capable of Initiating the Early Alzheimer-Like Pathology.

Sheng Y, Zhang L, Su SC, Tsai LH, Julius Zhu J.

Cereb Cortex. 2016 Jul;26(7):2937-51. doi: 10.1093/cercor/bhv032. Epub 2015 Jun 17.

PMID:
26088971
15.

CDK5 phosphorylates DRP1 and drives mitochondrial defects in NMDA-induced neuronal death.

Jahani-Asl A, Huang E, Irrcher I, Rashidian J, Ishihara N, Lagace DC, Slack RS, Park DS.

Hum Mol Genet. 2015 Aug 15;24(16):4573-83. doi: 10.1093/hmg/ddv188. Epub 2015 May 22.

PMID:
26002103
16.

Regulation of ERK Kinase by MEK1 Kinase Inhibition in the Brain.

Tassin TC, Benavides DR, Plattner F, Nishi A, Bibb JA.

J Biol Chem. 2015 Jun 26;290(26):16319-29. doi: 10.1074/jbc.M115.654897. Epub 2015 May 13.

17.

Failure to Recognize Novelty after Extended Methamphetamine Self-Administration Results from Loss of Long-Term Depression in the Perirhinal Cortex.

Scofield MD, Trantham-Davidson H, Schwendt M, Leong KC, Peters J, See RE, Reichel CM.

Neuropsychopharmacology. 2015 Oct;40(11):2526-35. doi: 10.1038/npp.2015.99. Epub 2015 Apr 13.

PMID:
25865928
18.

p35 and Rac1 underlie the neuroprotection and cognitive improvement induced by CDK5 silencing.

Posada-Duque RA, López-Tobón A, Piedrahita D, González-Billault C, Cardona-Gomez GP.

J Neurochem. 2015 Jul;134(2):354-70. doi: 10.1111/jnc.13127. Epub 2015 May 4.

19.

Loss of cyclin-dependent kinase 5 from parvalbumin interneurons leads to hyperinhibition, decreased anxiety, and memory impairment.

Rudenko A, Seo J, Hu J, Su SC, de Anda FC, Durak O, Ericsson M, Carlén M, Tsai LH.

J Neurosci. 2015 Feb 11;35(6):2372-83. doi: 10.1523/JNEUROSCI.0969-14.2015.

20.

Life extension factor klotho prevents mortality and enhances cognition in hAPP transgenic mice.

Dubal DB, Zhu L, Sanchez PE, Worden K, Broestl L, Johnson E, Ho K, Yu GQ, Kim D, Betourne A, Kuro-O M, Masliah E, Abraham CR, Mucke L.

J Neurosci. 2015 Feb 11;35(6):2358-71. doi: 10.1523/JNEUROSCI.5791-12.2015.

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