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Items: 1 to 20 of 69

1.

Typical Hus: Evidence of Acute Phase Complement Activation from a Daycare Outbreak.

Brady TM, Pruette C, Loeffler LF, Weidemann D, Strouse JJ, Gavriilaki E, Brodsky RA.

J Clin Exp Nephrol. 2016;1(2). pii: 11. Epub 2016 May 6.

2.

AMD and the alternative complement pathway: genetics and functional implications.

Tan PL, Bowes Rickman C, Katsanis N.

Hum Genomics. 2016 Jun 21;10(1):23. doi: 10.1186/s40246-016-0079-x. Review.

3.

Mutations in Complement Factor H Impair Alternative Pathway Regulation on Mouse Glomerular Endothelial Cells in Vitro.

Loeven MA, Rops AL, Lehtinen MJ, van Kuppevelt TH, Daha MR, Smith RJ, Bakker M, Berden JH, Rabelink TJ, Jokiranta TS, van der Vlag J.

J Biol Chem. 2016 Mar 4;291(10):4974-81. doi: 10.1074/jbc.M115.702506. Epub 2016 Jan 4.

PMID:
26728463
4.

The role of ADAMTS-13 activity and complement mutational analysis in differentiating acute thrombotic microangiopathies.

Phillips EH, Westwood JP, Brocklebank V, Wong EK, Tellez JO, Marchbank KJ, McGuckin S, Gale DP, Connolly J, Goodship TH, Kavanagh D, Scully MA.

J Thromb Haemost. 2016 Jan;14(1):175-85. doi: 10.1111/jth.13189. Epub 2016 Jan 11.

5.

Partial Complement Factor H Deficiency Associates with C3 Glomerulopathy and Thrombotic Microangiopathy.

Vernon KA, Ruseva MM, Cook HT, Botto M, Malik TH, Pickering MC.

J Am Soc Nephrol. 2016 May;27(5):1334-42. doi: 10.1681/ASN.2015030295. Epub 2015 Sep 15.

PMID:
26374608
6.

Efficacy of Targeted Complement Inhibition in Experimental C3 Glomerulopathy.

Ruseva MM, Peng T, Lasaro MA, Bouchard K, Liu-Chen S, Sun F, Yu ZX, Marozsan A, Wang Y, Pickering MC.

J Am Soc Nephrol. 2016 Feb;27(2):405-16. doi: 10.1681/ASN.2014121195. Epub 2015 Jun 5.

7.

The molecular and structural bases for the association of complement C3 mutations with atypical hemolytic uremic syndrome.

Martínez-Barricarte R, Heurich M, López-Perrote A, Tortajada A, Pinto S, López-Trascasa M, Sánchez-Corral P, Morgan BP, Llorca O, Harris CL, Rodríguez de Córdoba S.

Mol Immunol. 2015 Aug;66(2):263-73. doi: 10.1016/j.molimm.2015.03.248. Epub 2015 Apr 11.

8.

Analysis of rare variants in the CFH gene in patients with the cuticular drusen subtype of age-related macular degeneration.

Duvvari MR, Saksens NT, van de Ven JP, de Jong-Hesse Y, Schick T, Nillesen WM, Fauser S, Hoefsloot LH, Hoyng CB, de Jong EK, den Hollander AI.

Mol Vis. 2015 Mar 15;21:285-92. eCollection 2015.

9.

Rare genetic variants in the CFI gene are associated with advanced age-related macular degeneration and commonly result in reduced serum factor I levels.

Kavanagh D, Yu Y, Schramm EC, Triebwasser M, Wagner EK, Raychaudhuri S, Daly MJ, Atkinson JP, Seddon JM.

Hum Mol Genet. 2015 Jul 1;24(13):3861-70. doi: 10.1093/hmg/ddv091. Epub 2015 Mar 18.

10.

Complementing the Sugar Code: Role of GAGs and Sialic Acid in Complement Regulation.

Langford-Smith A, Day AJ, Bishop PN, Clark SJ.

Front Immunol. 2015 Feb 2;6:25. doi: 10.3389/fimmu.2015.00025. eCollection 2015. Review.

11.

Molecules Great and Small: The Complement System.

Mathern DR, Heeger PS.

Clin J Am Soc Nephrol. 2015 Sep 4;10(9):1636-50. doi: 10.2215/CJN.06230614. Epub 2015 Jan 7. Review.

12.

Expression of human complement factor H prevents age-related macular degeneration-like retina damage and kidney abnormalities in aged Cfh knockout mice.

Ding JD, Kelly U, Landowski M, Toomey CB, Groelle M, Miller C, Smith SG, Klingeborn M, Singhapricha T, Jiang H, Frank MM, Bowes Rickman C.

Am J Pathol. 2015 Jan;185(1):29-42. doi: 10.1016/j.ajpath.2014.08.026. Epub 2014 Nov 1.

13.

Autoantibodies to CD59, CD55, CD46 or CD35 are not associated with atypical haemolytic uraemic syndrome (aHUS).

Watson R, Wearmouth E, McLoughlin AC, Jackson A, Ward S, Bertram P, Bennaceur K, Barker CE, Pappworth IY, Kavanagh D, Lea SM, Atkinson JP, Goodship TH, Marchbank KJ.

Mol Immunol. 2015 Feb;63(2):287-96. doi: 10.1016/j.molimm.2014.07.017. Epub 2014 Aug 21.

14.

Dynamics of complement activation in aHUS and how to monitor eculizumab therapy.

Noris M, Galbusera M, Gastoldi S, Macor P, Banterla F, Bresin E, Tripodo C, Bettoni S, Donadelli R, Valoti E, Tedesco F, Amore A, Coppo R, Ruggenenti P, Gotti E, Remuzzi G.

Blood. 2014 Sep 11;124(11):1715-26. doi: 10.1182/blood-2014-02-558296. Epub 2014 Jul 18.

15.

New insights into disease-specific absence of complement factor H related protein C in mouse models of spontaneous autoimmune diseases.

Mehta G, Ferreira VP, Skerka C, Zipfel PF, Banda NK.

Mol Immunol. 2014 Nov;62(1):235-48. doi: 10.1016/j.molimm.2014.06.028. Epub 2014 Jul 15.

16.

Characterization of a factor H mutation that perturbs the alternative pathway of complement in a family with membranoproliferative GN.

Wong EK, Anderson HE, Herbert AP, Challis RC, Brown P, Reis GS, Tellez JO, Strain L, Fluck N, Humphrey A, Macleod A, Richards A, Ahlert D, Santibanez-Koref M, Barlow PN, Marchbank KJ, Harris CL, Goodship TH, Kavanagh D.

J Am Soc Nephrol. 2014 Nov;25(11):2425-33. doi: 10.1681/ASN.2013070732. Epub 2014 Apr 10.

17.
18.

American Society of Nephrology clinical pathological conference.

Meyers KE, Liapis H, Atta MG.

Clin J Am Soc Nephrol. 2014 Apr;9(4):818-28. doi: 10.2215/CJN.12481213. Epub 2014 Mar 20.

19.

CFH haplotypes and ARMS2, C2, C3, and CFB alleles show association with susceptibility to age-related macular degeneration in Mexicans.

Contreras AV, Zenteno JC, Fernández-López JC, Rodríguez-Corona U, Falfán-Valencia R, Sebastian L, Morales F, Ochoa-Contreras D, Carnevale A, Silva-Zolezzi I.

Mol Vis. 2014 Jan 14;20:105-16. eCollection 2014.

20.

Complement regulation in renal disease models.

Naik A, Sharma S, Quigg RJ.

Semin Nephrol. 2013 Nov;33(6):575-85. doi: 10.1016/j.semnephrol.2013.08.008. Review.

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