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Results: 16

1.

Functional contribution of the transcription factor ATF4 to the pathogenesis of amyotrophic lateral sclerosis.

Matus S, Lopez E, Valenzuela V, Nassif M, Hetz C.

PLoS One. 2013 Jul 18;8(7):e66672. doi: 10.1371/journal.pone.0066672. Print 2013.

PMID:
23874395
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Perk-dependent repression of miR-106b-25 cluster is required for ER stress-induced apoptosis.

Gupta S, Read DE, Deepti A, Cawley K, Gupta A, Oommen D, Verfaillie T, Matus S, Smith MA, Mott JL, Agostinis P, Hetz C, Samali A.

Cell Death Dis. 2012 Jun 28;3:e333. doi: 10.1038/cddis.2012.74.

PMID:
22739985
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Bim links ER stress and apoptosis in cells expressing mutant SOD1 associated with amyotrophic lateral sclerosis.

Soo KY, Atkin JD, Farg M, Walker AK, Horne MK, Nagley P.

PLoS One. 2012;7(4):e35413. doi: 10.1371/journal.pone.0035413. Epub 2012 Apr 16.

PMID:
22523592
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Serum caspase-9 levels are increased in patients with amyotrophic lateral sclerosis.

Iłżecka J.

Neurol Sci. 2012 Aug;33(4):825-9. doi: 10.1007/s10072-011-0837-4. Epub 2011 Nov 3.

PMID:
22048794
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

BAX inhibitor-1 regulates autophagy by controlling the IRE1α branch of the unfolded protein response.

Castillo K, Rojas-Rivera D, Lisbona F, Caballero B, Nassif M, Court FA, Schuck S, Ibar C, Walter P, Sierralta J, Glavic A, Hetz C.

EMBO J. 2011 Sep 16;30(21):4465-78. doi: 10.1038/emboj.2011.318.

PMID:
21926971
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Stressed to death: targeting endoplasmic reticulum stress response induced apoptosis in gliomas.

Johnson GG, White MC, Grimaldi M.

Curr Pharm Des. 2011;17(3):284-92. Review.

PMID:
21348829
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

TDP-43-induced death is associated with altered regulation of BIM and Bcl-xL and attenuated by caspase-mediated TDP-43 cleavage.

Suzuki H, Lee K, Matsuoka M.

J Biol Chem. 2011 Apr 15;286(15):13171-83. doi: 10.1074/jbc.M110.197483. Epub 2011 Feb 21.

PMID:
21339291
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Motor neuron trophic factors: therapeutic use in ALS?

Gould TW, Oppenheim RW.

Brain Res Rev. 2011 Jun 24;67(1-2):1-39. doi: 10.1016/j.brainresrev.2010.10.003. Epub 2010 Oct 21. Review.

PMID:
20971133
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Potential therapeutic benefits of strategies directed to mitochondria.

Camara AK, Lesnefsky EJ, Stowe DF.

Antioxid Redox Signal. 2010 Aug 1;13(3):279-347. doi: 10.1089/ars.2009.2788. Review.

PMID:
20001744
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Contrasting patterns of Bim induction and neuroprotection in Bim-deficient mice between hippocampus and neocortex after status epilepticus.

Murphy BM, Engel T, Paucard A, Hatazaki S, Mouri G, Tanaka K, Tuffy LP, Jimenez-Mateos EM, Woods I, Dunleavy M, Bonner HP, Meller R, Simon RP, Strasser A, Prehn JH, Henshall DC.

Cell Death Differ. 2010 Mar;17(3):459-68. doi: 10.1038/cdd.2009.134. Epub 2009 Sep 25.

PMID:
19779495
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

XBP-1 deficiency in the nervous system protects against amyotrophic lateral sclerosis by increasing autophagy.

Hetz C, Thielen P, Matus S, Nassif M, Court F, Kiffin R, Martinez G, Cuervo AM, Brown RH, Glimcher LH.

Genes Dev. 2009 Oct 1;23(19):2294-306. doi: 10.1101/gad.1830709. Epub 2009 Sep 17.

PMID:
19762508
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

PUMA, a potent killer with or without p53.

Yu J, Zhang L.

Oncogene. 2008 Dec;27 Suppl 1:S71-83. doi: 10.1038/onc.2009.45. Review.

PMID:
19641508
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Genetic modulation of apoptotic pathways fails to alter disease course in tripeptidyl-peptidase 1 deficient mice.

Kim KH, Sleat DE, Bernard O, Lobel P.

Neurosci Lett. 2009 Mar 27;453(1):27-30. doi: 10.1016/j.neulet.2009.01.072. Epub 2009 Feb 4.

PMID:
19429009
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Histone deacetylase inhibitors prevent p53-dependent and p53-independent Bax-mediated neuronal apoptosis through two distinct mechanisms.

Uo T, Veenstra TD, Morrison RS.

J Neurosci. 2009 Mar 4;29(9):2824-32. doi: 10.1523/JNEUROSCI.6186-08.2009.

PMID:
19261878
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Deletion of the BH3-only protein puma protects motoneurons from ER stress-induced apoptosis and delays motoneuron loss in ALS mice.

Kieran D, Woods I, Villunger A, Strasser A, Prehn JH.

Proc Natl Acad Sci U S A. 2007 Dec 18;104(51):20606-11. Epub 2007 Dec 11.

PMID:
18077368
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Diminishing apoptosis by deletion of Bax or overexpression of Bcl-2 does not protect against infectious prion toxicity in vivo.

Steele AD, King OD, Jackson WS, Hetz CA, Borkowski AW, Thielen P, Wollmann R, Lindquist S.

J Neurosci. 2007 Nov 21;27(47):13022-7.

PMID:
18032675
[PubMed - indexed for MEDLINE]
Free PMC Article

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