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Results: 1 to 20 of 40

1.

Structure of the periplasmic adaptor protein from a major facilitator superfamily (MFS) multidrug efflux pump.

Hinchliffe P, Greene NP, Paterson NG, Crow A, Hughes C, Koronakis V.

FEBS Lett. 2014 Aug 25;588(17):3147-53. doi: 10.1016/j.febslet.2014.06.055. Epub 2014 Jul 1.

PMID:
24996185
[PubMed - in process]
Free PMC Article
2.

Structure of an atypical periplasmic adaptor from a multidrug efflux pump of the spirochete Borrelia burgdorferi.

Greene NP, Hinchliffe P, Crow A, Ababou A, Hughes C, Koronakis V.

FEBS Lett. 2013 Sep 17;587(18):2984-8. doi: 10.1016/j.febslet.2013.06.056. Epub 2013 Jul 10.

PMID:
23851070
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Structure, Function and Regulation of Outer Membrane Proteins Involved in Drug Transport in Enterobactericeae: the OmpF/C - TolC Case.

Masi M, Pagès JM.

Open Microbiol J. 2013;7:22-33. doi: 10.2174/1874285801307010022. Epub 2013 Mar 22.

PMID:
23569467
[PubMed]
Free PMC Article
4.

Tripartite efflux pumps: energy is required for dissociation, but not assembly or opening of the outer membrane channel of the pump.

Janganan TK, Bavro VN, Zhang L, Borges-Walmsley MI, Walmsley AR.

Mol Microbiol. 2013 May;88(3):590-602. doi: 10.1111/mmi.12211. Epub 2013 Apr 9.

PMID:
23565750
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

On the role of TolC in multidrug efflux: the function and assembly of AcrAB-TolC tolerate significant depletion of intracellular TolC protein.

Krishnamoorthy G, Tikhonova EB, Dhamdhere G, Zgurskaya HI.

Mol Microbiol. 2013 Mar;87(5):982-97. doi: 10.1111/mmi.12143. Epub 2013 Jan 21.

PMID:
23331412
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Assembly and channel opening of outer membrane protein in tripartite drug efflux pumps of Gram-negative bacteria.

Xu Y, Moeller A, Jun SY, Le M, Yoon BY, Kim JS, Lee K, Ha NC.

J Biol Chem. 2012 Apr 6;287(15):11740-50. doi: 10.1074/jbc.M111.329375. Epub 2012 Feb 3.

PMID:
22308040
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Involvement of the AcrAB-TolC efflux pump in the resistance, fitness, and virulence of Enterobacter cloacae.

Pérez A, Poza M, Fernández A, Fernández Mdel C, Mallo S, Merino M, Rumbo-Feal S, Cabral MP, Bou G.

Antimicrob Agents Chemother. 2012 Apr;56(4):2084-90. doi: 10.1128/AAC.05509-11. Epub 2012 Jan 30.

PMID:
22290971
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Mechanism and Function of the Outer Membrane Channel TolC in Multidrug Resistance and Physiology of Enterobacteria.

Zgurskaya HI, Krishnamoorthy G, Ntreh A, Lu S.

Front Microbiol. 2011 Sep 16;2:189. doi: 10.3389/fmicb.2011.00189. eCollection 2011.

PMID:
21954395
[PubMed]
Free PMC Article
9.

Novel ATP-driven pathway of glycolipid export involving TolC protein.

Staron P, Forchhammer K, Maldener I.

J Biol Chem. 2011 Nov 4;286(44):38202-10. doi: 10.1074/jbc.M111.269332. Epub 2011 Sep 14.

PMID:
21917923
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Protein Secretion Systems in Pseudomonas aeruginosa: An Essay on Diversity, Evolution, and Function.

Filloux A.

Front Microbiol. 2011 Jul 18;2:155. doi: 10.3389/fmicb.2011.00155. eCollection 2011.

PMID:
21811488
[PubMed]
Free PMC Article
11.

Structure and mechanism of RND-type multidrug efflux pumps.

Nikaido H.

Adv Enzymol Relat Areas Mol Biol. 2011;77:1-60. Review. No abstract available.

PMID:
21692366
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Evidence for the assembly of a bacterial tripartite multidrug pump with a stoichiometry of 3:6:3.

Janganan TK, Bavro VN, Zhang L, Matak-Vinkovic D, Barrera NP, Venien-Bryan C, Robinson CV, Borges-Walmsley MI, Walmsley AR.

J Biol Chem. 2011 Jul 29;286(30):26900-12. doi: 10.1074/jbc.M111.246595. Epub 2011 May 24.

PMID:
21610073
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Sequential mechanism of assembly of multidrug efflux pump AcrAB-TolC.

Tikhonova EB, Yamada Y, Zgurskaya HI.

Chem Biol. 2011 Apr 22;18(4):454-63. doi: 10.1016/j.chembiol.2011.02.011.

PMID:
21513882
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Funnel-like hexameric assembly of the periplasmic adapter protein in the tripartite multidrug efflux pump in gram-negative bacteria.

Xu Y, Lee M, Moeller A, Song S, Yoon BY, Kim HM, Jun SY, Lee K, Ha NC.

J Biol Chem. 2011 May 20;286(20):17910-20. doi: 10.1074/jbc.M111.238535. Epub 2011 Mar 29.

PMID:
21454662
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Functional implications of an intermeshing cogwheel-like interaction between TolC and MacA in the action of macrolide-specific efflux pump MacAB-TolC.

Xu Y, Song S, Moeller A, Kim N, Piao S, Sim SH, Kang M, Yu W, Cho HS, Chang I, Lee K, Ha NC.

J Biol Chem. 2011 Apr 15;286(15):13541-9. doi: 10.1074/jbc.M110.202598. Epub 2011 Feb 16.

PMID:
21325274
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Structures of sequential open states in a symmetrical opening transition of the TolC exit duct.

Pei XY, Hinchliffe P, Symmons MF, Koronakis E, Benz R, Hughes C, Koronakis V.

Proc Natl Acad Sci U S A. 2011 Feb 1;108(5):2112-7. doi: 10.1073/pnas.1012588108. Epub 2011 Jan 18.

PMID:
21245342
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Opening of the outer membrane protein channel in tripartite efflux pumps is induced by interaction with the membrane fusion partner.

Janganan TK, Zhang L, Bavro VN, Matak-Vinkovic D, Barrera NP, Burton MF, Steel PG, Robinson CV, Borges-Walmsley MI, Walmsley AR.

J Biol Chem. 2011 Feb 18;286(7):5484-93. doi: 10.1074/jbc.M110.187658. Epub 2010 Nov 29.

PMID:
21115481
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Functional relationships between the AcrA hairpin tip region and the TolC aperture tip region for the formation of the bacterial tripartite efflux pump AcrAB-TolC.

Kim HM, Xu Y, Lee M, Piao S, Sim SH, Ha NC, Lee K.

J Bacteriol. 2010 Sep;192(17):4498-503. doi: 10.1128/JB.00334-10. Epub 2010 Jun 25.

PMID:
20581201
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Metal-induced conformational changes in ZneB suggest an active role of membrane fusion proteins in efflux resistance systems.

De Angelis F, Lee JK, O'Connell JD 3rd, Miercke LJ, Verschueren KH, Srinivasan V, Bauvois C, Govaerts C, Robbins RA, Ruysschaert JM, Stroud RM, Vandenbussche G.

Proc Natl Acad Sci U S A. 2010 Jun 15;107(24):11038-43. doi: 10.1073/pnas.1003908107. Epub 2010 Jun 1.

PMID:
20534468
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

AcrA suppressor alterations reverse the drug hypersensitivity phenotype of a TolC mutant by inducing TolC aperture opening.

Weeks JW, Celaya-Kolb T, Pecora S, Misra R.

Mol Microbiol. 2010 Mar;75(6):1468-83. doi: 10.1111/j.1365-2958.2010.07068.x. Epub 2010 Feb 1.

PMID:
20132445
[PubMed - indexed for MEDLINE]
Free PMC Article

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