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Detoxifying Enzymes at the Cross-Roads of Inflammation, Oxidative Stress, and Drug Hypersensitivity: Role of Glutathione Transferase P1-1 and Aldose Reductase.

Sánchez-Gómez FJ, Díez-Dacal B, García-Martín E, Agúndez JA, Pajares MA, Pérez-Sala D.

Front Pharmacol. 2016 Aug 4;7:237. doi: 10.3389/fphar.2016.00237. eCollection 2016.


The NAD(+) precursor nicotinamide riboside decreases exercise performance in rats.

Kourtzidis IA, Stoupas AT, Gioris IS, Veskoukis AS, Margaritelis NV, Tsantarliotou M, Taitzoglou I, Vrabas IS, Paschalis V, Kyparos A, Nikolaidis MG.

J Int Soc Sports Nutr. 2016 Aug 2;13:32. doi: 10.1186/s12970-016-0143-x. eCollection 2016.


Emerging therapeutic roles for NAD(+) metabolism in mitochondrial and age-related disorders.

Srivastava S.

Clin Transl Med. 2016 Dec;5(1):25. doi: 10.1186/s40169-016-0104-7. Epub 2016 Jul 27. Review.


In vivo (31) P MRS assessment of intracellular NAD metabolites and NAD(+) /NADH redox state in human brain at 4 T.

Lu M, Zhu XH, Chen W.

NMR Biomed. 2016 Jul;29(7):1010-7. doi: 10.1002/nbm.3559. Epub 2016 Jun 3.


Nicotinamide Mononucleotide Adenylyl Transferase 2: A Promising Diagnostic and Therapeutic Target for Colorectal Cancer.

Cui C, Qi J, Deng Q, Chen R, Zhai D, Yu J.

Biomed Res Int. 2016;2016:1804137. doi: 10.1155/2016/1804137. Epub 2016 Apr 27.


The Peroxisomal NAD Carrier from Arabidopsis Imports NAD in Exchange with AMP.

van Roermund CW, Schroers MG, Wiese J, Facchinelli F, Kurz S, Wilkinson S, Charton L, Wanders RJ, Waterham HR, Weber AP, Link N.

Plant Physiol. 2016 Jul;171(3):2127-39. doi: 10.1104/pp.16.00540. Epub 2016 May 2.


Cell-Line Selectivity Improves the Predictive Power of Pharmacogenomic Analyses and Helps Identify NADPH as Biomarker for Ferroptosis Sensitivity.

Shimada K, Hayano M, Pagano NC, Stockwell BR.

Cell Chem Biol. 2016 Feb 18;23(2):225-35. doi: 10.1016/j.chembiol.2015.11.016. Epub 2016 Feb 4.


Functional annotation of rare gene aberration drivers of pancreatic cancer.

Tsang YH, Dogruluk T, Tedeschi PM, Wardwell-Ozgo J, Lu H, Espitia M, Nair N, Minelli R, Chong Z, Chen F, Chang QE, Dennison JB, Dogruluk A, Li M, Ying H, Bertino JR, Gingras MC, Ittmann M, Kerrigan J, Chen K, Creighton CJ, Eterovic K, Mills GB, Scott KL.

Nat Commun. 2016 Jan 25;7:10500. doi: 10.1038/ncomms10500.


Energy disruptors: rising stars in anticancer therapy?

Bost F, Decoux-Poullot AG, Tanti JF, Clavel S.

Oncogenesis. 2016 Jan 18;5:e188. doi: 10.1038/oncsis.2015.46. Review.


Ligand steals spotlight from metal to orchestrate hydrogen production.

Dempsey JL.

Proc Natl Acad Sci U S A. 2016 Jan 19;113(3):478-9. doi: 10.1073/pnas.1522759113. Epub 2016 Jan 8. No abstract available.


Nickel phlorin intermediate formed by proton-coupled electron transfer in hydrogen evolution mechanism.

Solis BH, Maher AG, Dogutan DK, Nocera DG, Hammes-Schiffer S.

Proc Natl Acad Sci U S A. 2016 Jan 19;113(3):485-92. doi: 10.1073/pnas.1521834112. Epub 2015 Dec 10.


Nmnat1-Rbp7 Is a Conserved Fusion-Protein That Combines NAD+ Catalysis of Nmnat1 with Subcellular Localization of Rbp7.

Chen H, Babino D, Schoenbichler SA, Arkhipova V, Töchterle S, Martin F, Huck CW, von Lintig J, Meyer D.

PLoS One. 2015 Nov 30;10(11):e0143825. doi: 10.1371/journal.pone.0143825. eCollection 2015.


Regulation of a Protein Acetyltransferase in Myxococcus xanthus by the Coenzyme NADP.

Liu XX, Liu WB, Ye BC.

J Bacteriol. 2015 Nov 23;198(4):623-32. doi: 10.1128/JB.00661-15.


Methionine Metabolism Alters Oxidative Stress Resistance via the Pentose Phosphate Pathway.

Campbell K, Vowinckel J, Keller MA, Ralser M.

Antioxid Redox Signal. 2016 Apr 1;24(10):543-7. doi: 10.1089/ars.2015.6516. Epub 2016 Mar 15.


Intracellular Mono-ADP-Ribosylation in Signaling and Disease.

Bütepage M, Eckei L, Verheugd P, Lüscher B.

Cells. 2015 Sep 25;4(4):569-95. doi: 10.3390/cells4040569. Review.


Acute Tumor Lactate Perturbations as a Biomarker of Genotoxic Stress: Development of a Biochemical Model.

Sandulache VC, Chen Y, Skinner HD, Lu T, Feng L, Court LE, Myers JN, Meyn RE, Fuller CD, Bankson JA, Lai SY.

Mol Cancer Ther. 2015 Dec;14(12):2901-8. doi: 10.1158/1535-7163.MCT-15-0217. Epub 2015 Sep 16.


NADPH-generating systems in bacteria and archaea.

Spaans SK, Weusthuis RA, van der Oost J, Kengen SW.

Front Microbiol. 2015 Jul 29;6:742. doi: 10.3389/fmicb.2015.00742. eCollection 2015. Review.


Determination of the Cytosolic NADPH/NADP Ratio in Saccharomyces cerevisiae using Shikimate Dehydrogenase as Sensor Reaction.

Zhang J, ten Pierick A, van Rossum HM, Seifar RM, Ras C, Daran JM, Heijnen JJ, Wahl SA.

Sci Rep. 2015 Aug 5;5:12846. doi: 10.1038/srep12846.


Suppression of Cytosolic NADPH Pool by Thionicotinamide Increases Oxidative Stress and Synergizes with Chemotherapy.

Tedeschi PM, Lin H, Gounder M, Kerrigan JE, Abali EE, Scotto K, Bertino JR.

Mol Pharmacol. 2015 Oct;88(4):720-7. doi: 10.1124/mol.114.096727. Epub 2015 Jul 28.


Short-term diabetic hyperglycemia suppresses celiac ganglia neurotransmission, thereby impairing sympathetically mediated glucagon responses.

Mundinger TO, Cooper E, Coleman MP, Taborsky GJ Jr.

Am J Physiol Endocrinol Metab. 2015 Aug 1;309(3):E246-55. doi: 10.1152/ajpendo.00140.2015. Epub 2015 Jun 2.

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