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Items: 1 to 20 of 32


Cholesterol modulates CFTR confinement in the plasma membrane of primary epithelial cells.

Abu-Arish A, Pandzic E, Goepp J, Matthes E, Hanrahan JW, Wiseman PW.

Biophys J. 2015 Jul 7;109(1):85-94. doi: 10.1016/j.bpj.2015.04.042.


Calmodulin and CaMKII modulate ENaC activity by regulating the association of MARCKS and the cytoskeleton with the apical membrane.

Alli AA, Bao HF, Liu BC, Yu L, Aldrugh S, Montgomery DS, Ma HP, Eaton DC.

Am J Physiol Renal Physiol. 2015 Sep 1;309(5):F456-63. doi: 10.1152/ajprenal.00631.2014. Epub 2015 Jul 1.


Filamin-a increases the stability and plasma membrane expression of polycystin-2.

Wang Q, Zheng W, Wang Z, Yang J, Hussein S, Tang J, Chen XZ.

PLoS One. 2015 Apr 10;10(4):e0123018. doi: 10.1371/journal.pone.0123018. eCollection 2015.


Filamin A interaction with the CXCR4 third intracellular loop regulates endocytosis and signaling of WT and WHIM-like receptors.

Gómez-Moutón C, Fischer T, Peregil RM, Jiménez-Baranda S, Stossel TP, Nakamura F, Mañes S.

Blood. 2015 Feb 12;125(7):1116-25. doi: 10.1182/blood-2014-09-601807. Epub 2014 Oct 29.


Functional interaction with filamin A and intracellular Ca2+ enhance the surface membrane expression of a small-conductance Ca2+-activated K+ (SK2) channel.

Rafizadeh S, Zhang Z, Woltz RL, Kim HJ, Myers RE, Lu L, Tuteja D, Singapuri A, Bigdeli AA, Harchache SB, Knowlton AA, Yarov-Yarovoy V, Yamoah EN, Chiamvimonvat N.

Proc Natl Acad Sci U S A. 2014 Jul 8;111(27):9989-94. doi: 10.1073/pnas.1323541111. Epub 2014 Jun 20.


Interference with ubiquitination in CFTR modifies stability of core glycosylated and cell surface pools.

Lee S, Henderson MJ, Schiffhauer E, Despanie J, Henry K, Kang PW, Walker D, McClure ML, Wilson L, Sorscher EJ, Zeitlin PL.

Mol Cell Biol. 2014 Jul;34(14):2554-65.


Apical localisation of crumbs in the boundary cells of the Drosophila hindgut is independent of its canonical interaction partner stardust.

Kumichel A, Knust E.

PLoS One. 2014 Apr 7;9(4):e94038. doi: 10.1371/journal.pone.0094038. eCollection 2014.


Periventricular Heterotopia: Shuttling of Proteins through Vesicles and Actin in Cortical Development and Disease.

Sheen VL.

Scientifica (Cairo). 2012;2012:480129. doi: 10.6064/2012/480129. Epub 2012 Oct 22. Review.


RACK1 interacts with filamin-A to regulate plasma membrane levels of the cystic fibrosis transmembrane conductance regulator.

Smith L, Litman P, Kohli E, Amick J, Page RC, Misra S, Liedtke CM.

Am J Physiol Cell Physiol. 2013 Jul 1;305(1):C111-20. doi: 10.1152/ajpcell.00026.2013. Epub 2013 May 1.


Hypertension-linked mutation of α-adducin increases CFTR surface expression and activity in HEK and cultured rat distal convoluted tubule cells.

Mondini A, Sassone F, Civello DA, Garavaglia ML, Bazzini C, Rodighiero S, Vezzoli V, Conti F, Torielli L, Capasso G, Paulmichl M, Meyer G.

PLoS One. 2012;7(12):e52014. doi: 10.1371/journal.pone.0052014. Epub 2012 Dec 21.


Filamin interacts with epithelial sodium channel and inhibits its channel function.

Wang Q, Dai XQ, Li Q, Tuli J, Liang G, Li SS, Chen XZ.

J Biol Chem. 2013 Jan 4;288(1):264-73. doi: 10.1074/jbc.M112.396408. Epub 2012 Nov 16.


Reduced PDZ interactions of rescued ΔF508CFTR increases its cell surface mobility.

Valentine CD, Lukacs GL, Verkman AS, Haggie PM.

J Biol Chem. 2012 Dec 21;287(52):43630-8. doi: 10.1074/jbc.M112.421172. Epub 2012 Oct 31.


Keratin K18 increases cystic fibrosis transmembrane conductance regulator (CFTR) surface expression by binding to its C-terminal hydrophobic patch.

Duan Y, Sun Y, Zhang F, Zhang WK, Wang D, Wang Y, Cao X, Hu W, Xie C, Cuppoletti J, Magin TM, Wang H, Wu Z, Li N, Huang P.

J Biol Chem. 2012 Nov 23;287(48):40547-59. doi: 10.1074/jbc.M112.403584. Epub 2012 Oct 8.


Physiology of epithelial chloride and fluid secretion.

Frizzell RA, Hanrahan JW.

Cold Spring Harb Perspect Med. 2012 Jun;2(6):a009563. doi: 10.1101/cshperspect.a009563.


The transcription factor GCF2 is an upstream repressor of the small GTPAse RhoA, regulating membrane protein trafficking, sensitivity to doxorubicin, and resistance to cisplatin.

Shen DW, Pouliot LM, Gillet JP, Ma W, Johnson AC, Hall MD, Gottesman MM.

Mol Pharm. 2012 Jun 4;9(6):1822-33. doi: 10.1021/mp300153z. Epub 2012 May 17.


A switch of G protein-coupled receptor binding preference from phosphoinositide 3-kinase (PI3K)-p85 to filamin A negatively controls the PI3K pathway.

Najib S, Saint-Laurent N, Estève JP, Schulz S, Boutet-Robinet E, Fourmy D, Lättig J, Mollereau C, Pyronnet S, Susini C, Bousquet C.

Mol Cell Biol. 2012 Mar;32(5):1004-16. doi: 10.1128/MCB.06252-11. Epub 2011 Dec 27.


Disruption of cytokeratin-8 interaction with F508del-CFTR corrects its functional defect.

Colas J, Faure G, Saussereau E, Trudel S, Rabeh WM, Bitam S, Guerrera IC, Fritsch J, Sermet-Gaudelus I, Davezac N, Brouillard F, Lukacs GL, Herrmann H, Ollero M, Edelman A.

Hum Mol Genet. 2012 Feb 1;21(3):623-34. doi: 10.1093/hmg/ddr496. Epub 2011 Oct 28.


Filamin A protein interacts with human immunodeficiency virus type 1 Gag protein and contributes to productive particle assembly.

Cooper J, Liu L, Woodruff EA, Taylor HE, Goodwin JS, D'Aquila RT, Spearman P, Hildreth JE, Dong X.

J Biol Chem. 2011 Aug 12;286(32):28498-510. doi: 10.1074/jbc.M111.239053. Epub 2011 Jun 24.


Defective adenosine-stimulated cAMP production in cystic fibrosis airway epithelia: a novel role for CFTR in cell signaling.

Watson MJ, Worthington EN, Clunes LA, Rasmussen JE, Jones L, Tarran R.

FASEB J. 2011 Sep;25(9):2996-3003. doi: 10.1096/fj.11-186080. Epub 2011 May 31.


Protein biomarkers in cystic fibrosis research: where next?

Pattison SH, Elborn JS.

Genome Med. 2010 Dec 16;2(12):88. doi: 10.1186/gm209.

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