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Results: 19

1.

The role of innate and adaptive immunity in Parkinson's disease.

Kannarkat GT, Boss JM, Tansey MG.

J Parkinsons Dis. 2013;3(4):493-514. doi: 10.3233/JPD-130250. Review.

PMID:
24275605
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Genetic basis of Parkinson's disease: inheritance, penetrance, and expression.

Schulte C, Gasser T.

Appl Clin Genet. 2011 Jun 1;4:67-80. doi: 10.2147/TACG.S11639. Print 2011.

PMID:
23776368
[PubMed]
Free PMC Article
3.

The genetics of Parkinson's disease: progress and therapeutic implications.

Singleton AB, Farrer MJ, Bonifati V.

Mov Disord. 2013 Jan;28(1):14-23. doi: 10.1002/mds.25249. Review.

PMID:
23389780
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

LRRK2 inhibition attenuates microglial inflammatory responses.

Moehle MS, Webber PJ, Tse T, Sukar N, Standaert DG, DeSilva TM, Cowell RM, West AB.

J Neurosci. 2012 Feb 1;32(5):1602-11. doi: 10.1523/JNEUROSCI.5601-11.2012.

PMID:
22302802
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Genomewide linkage study of modifiers of LRRK2-related Parkinson's disease.

Latourelle JC, Hendricks AE, Pankratz N, Wilk JB, Halter C, Nichols WC, Gusella JF, Destefano AL, Myers RH, Foroud T; PSG-Progeni GenePD Investigators, Coordinators, and Molecular Genetic Laboratories.

Mov Disord. 2011 Sep;26(11):2039-44. doi: 10.1002/mds.23781. Epub 2011 Jun 9.

PMID:
21661047
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Genetic LRRK2 models of Parkinson's disease: Dissecting the pathogenic pathway and exploring clinical applications.

Yue Z, Lachenmayer ML.

Mov Disord. 2011 Jul;26(8):1386-97. doi: 10.1002/mds.23737. Epub 2011 Apr 29. Review.

PMID:
21538530
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Genetic testing and Parkinson disease: assessment of patient knowledge, attitudes, and interest.

Falcone DC, Wood EM, Xie SX, Siderowf A, Van Deerlin VM.

J Genet Couns. 2011 Aug;20(4):384-95. doi: 10.1007/s10897-011-9362-0. Epub 2011 Apr 8.

PMID:
21476119
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Substantia nigra hyperechogenicity with LRRK2 G2019S mutations.

Brüggemann N, Hagenah J, Stanley K, Klein C, Wang C, Raymond D, Ozelius L, Bressman S, Saunders-Pullman R.

Mov Disord. 2011 Apr;26(5):885-8. doi: 10.1002/mds.23644. Epub 2011 Feb 10.

PMID:
21312285
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

α-Synuclein, leucine-rich repeat kinase-2, and manganese in the pathogenesis of Parkinson disease.

Covy JP, Giasson BI.

Neurotoxicology. 2011 Oct;32(5):622-9. doi: 10.1016/j.neuro.2011.01.003. Epub 2011 Jan 14. Review.

PMID:
21238487
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Parkin Exon Rearrangements and Sequence Variants in LRRK2 Mutations Carriers: Analysis on a Possible Modifier Effect on LRRK2 Penetrance.

Solla P, Cannas A, Floris G, Murru MR, Corongiu D, Tranquilli S, Cuccu S, Rolesu M, Marrosu F, Marrosu MG.

Parkinsons Dis. 2010 Aug 19;2010:537698. doi: 10.4061/2010/537698.

PMID:
20976090
[PubMed]
Free PMC Article
11.

The genetics of Parkinson disease.

Bekris LM, Mata IF, Zabetian CP.

J Geriatr Psychiatry Neurol. 2010 Dec;23(4):228-42. doi: 10.1177/0891988710383572. Epub 2010 Oct 11. Review.

PMID:
20938043
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Genomewide association study for onset age in Parkinson disease.

Latourelle JC, Pankratz N, Dumitriu A, Wilk JB, Goldwurm S, Pezzoli G, Mariani CB, DeStefano AL, Halter C, Gusella JF, Nichols WC, Myers RH, Foroud T; PROGENI Investigators, Coordinators and Molecular Genetic Laboratories; GenePD Investigators, Coordinators and Molecular Genetic Laboratories.

BMC Med Genet. 2009 Sep 22;10:98. doi: 10.1186/1471-2350-10-98.

PMID:
19772629
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Leucine-rich repeat kinase 2 (LRRK2): a key player in the pathogenesis of Parkinson's disease.

Gandhi PN, Chen SG, Wilson-Delfosse AL.

J Neurosci Res. 2009 May 1;87(6):1283-95. doi: 10.1002/jnr.21949. Review.

PMID:
19025767
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Clinical and pathological characteristics of patients with leucine-rich repeat kinase-2 mutations.

Covy JP, Yuan W, Waxman EA, Hurtig HI, Van Deerlin VM, Giasson BI.

Mov Disord. 2009 Jan 15;24(1):32-9. doi: 10.1002/mds.22096.

PMID:
19006185
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

LRRK2 in Parkinson's disease - drawing the curtain of penetrance: a commentary.

Krüger R.

BMC Med. 2008 Nov 5;6:33. doi: 10.1186/1741-7015-6-33.

PMID:
18986509
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

The Gly2019Ser mutation in LRRK2 is not fully penetrant in familial Parkinson's disease: the GenePD study.

Latourelle JC, Sun M, Lew MF, Suchowersky O, Klein C, Golbe LI, Mark MH, Growdon JH, Wooten GF, Watts RL, Guttman M, Racette BA, Perlmutter JS, Ahmed A, Shill HA, Singer C, Goldwurm S, Pezzoli G, Zini M, Saint-Hilaire MH, Hendricks AE, Williamson S, Nagle MW, Wilk JB, Massood T, Huskey KW, Laramie JM, DeStefano AL, Baker KB, Itin I, Litvan I, Nicholson G, Corbett A, Nance M, Drasby E, Isaacson S, Burn DJ, Chinnery PF, Pramstaller PP, Al-hinti J, Moller AT, Ostergaard K, Sherman SJ, Roxburgh R, Snow B, Slevin JT, Cambi F, Gusella JF, Myers RH.

BMC Med. 2008 Nov 5;6:32. doi: 10.1186/1741-7015-6-32.

PMID:
18986508
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Phenotype, genotype, and worldwide genetic penetrance of LRRK2-associated Parkinson's disease: a case-control study.

Healy DG, Falchi M, O'Sullivan SS, Bonifati V, Durr A, Bressman S, Brice A, Aasly J, Zabetian CP, Goldwurm S, Ferreira JJ, Tolosa E, Kay DM, Klein C, Williams DR, Marras C, Lang AE, Wszolek ZK, Berciano J, Schapira AH, Lynch T, Bhatia KP, Gasser T, Lees AJ, Wood NW; International LRRK2 Consortium.

Lancet Neurol. 2008 Jul;7(7):583-90. doi: 10.1016/S1474-4422(08)70117-0. Epub 2008 Jun 6.

PMID:
18539534
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Etiology and pathophysiology of frontotemporal dementia, Parkinson disease and Alzheimer disease: lessons from genetic studies.

Wider C, Wszolek ZK.

Neurodegener Dis. 2008;5(3-4):122-5. doi: 10.1159/000113680. Epub 2008 Mar 6. Review.

PMID:
18322368
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Dynamic and redundant regulation of LRRK2 and LRRK1 expression.

Biskup S, Moore DJ, Rea A, Lorenz-Deperieux B, Coombes CE, Dawson VL, Dawson TM, West AB.

BMC Neurosci. 2007 Nov 28;8:102.

PMID:
18045479
[PubMed - indexed for MEDLINE]
Free PMC Article

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