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Results: 1 to 20 of 30

1.

Targeting the sheddase activity of ADAM17 by an anti-ADAM17 antibody D1(A12) inhibits head and neck squamous cell carcinoma cell proliferation and motility via blockage of bradykinin induced HERs transactivation.

Huang Y, Benaich N, Tape C, Kwok HF, Murphy G.

Int J Biol Sci. 2014 Jun 21;10(7):702-14. doi: 10.7150/ijbs.9326. eCollection 2014.

PMID:
25013379
[PubMed - in process]
Free PMC Article
2.

Allosteric Modulation of G Protein Coupled Receptors by Cytoplasmic, Transmembrane and Extracellular Ligands.

Yanamala N, Klein-Seetharaman J.

Pharmaceuticals (Basel). 2010 Oct 1;3(10):3324-3342.

PMID:
24009470
[PubMed]
Free PMC Article
3.

Targeting TORC1/2 enhances sensitivity to EGFR inhibitors in head and neck cancer preclinical models.

Cassell A, Freilino ML, Lee J, Barr S, Wang L, Panahandeh MC, Thomas SM, Grandis JR.

Neoplasia. 2012 Nov;14(11):1005-14.

PMID:
23226094
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Molecular phenotype predicts sensitivity of squamous cell carcinoma of the head and neck to epidermal growth factor receptor inhibition.

Young NR, Liu J, Pierce C, Wei TF, Grushko T, Olopade OI, Liu W, Shen C, Seiwert TY, Cohen EE.

Mol Oncol. 2013 Jun;7(3):359-68. doi: 10.1016/j.molonc.2012.11.001. Epub 2012 Nov 14.

PMID:
23200321
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

The bradykinin B(2) receptor induces multiple cellular responses leading to the proliferation of human renal carcinoma cell lines.

Kramarenko II, Morinelli TA, Bunni MA, Raymond JR Sr, Garnovskaya MN.

Cancer Manag Res. 2012;4:195-205. doi: 10.2147/CMAR.S31847. Epub 2012 Jul 26.

PMID:
22904641
[PubMed]
Free PMC Article
6.

Serum biomarker modulation following molecular targeting of epidermal growth factor and cyclooxygenase pathways: a pilot randomized trial in head and neck cancer.

Moskowitz HS, Gooding WE, Thomas SM, Freilino ML, Gross N, Argiris A, Grandis JR, Ferris RL.

Oral Oncol. 2012 Nov;48(11):1136-45. doi: 10.1016/j.oraloncology.2012.05.015. Epub 2012 Jun 23.

PMID:
22732263
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Antitumor mechanisms of targeting the PDK1 pathway in head and neck cancer.

Bhola NE, Freilino ML, Joyce SC, Sen M, Thomas SM, Sahu A, Cassell A, Chen CS, Grandis JR.

Mol Cancer Ther. 2012 Jun;11(6):1236-46. doi: 10.1158/1535-7163.MCT-11-0936. Epub 2012 Apr 5.

PMID:
22491800
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

The cytoplasmic rhodopsin-protein interface: potential for drug discovery.

Yanamala N, Gardner E, Riciutti A, Klein-Seetharaman J.

Curr Drug Targets. 2012 Jan;13(1):3-14. Review.

PMID:
21777183
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Targeting GPCR-mediated p70S6K activity may improve head and neck cancer response to cetuximab.

Bhola NE, Thomas SM, Freilino M, Joyce S, Sahu A, Maxwell J, Argiris A, Seethala R, Grandis JR.

Clin Cancer Res. 2011 Aug 1;17(15):4996-5004. doi: 10.1158/1078-0432.CCR-10-3406. Epub 2011 Jun 8.

PMID:
21653688
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

In vivo invasion of head and neck squamous cell carcinoma cells does not require macrophages.

Smirnova T, Adomako A, Locker J, Van Rooijen N, Prystowsky MB, Segall JE.

Am J Pathol. 2011 Jun;178(6):2857-65. doi: 10.1016/j.ajpath.2011.02.030.

PMID:
21641405
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Dual blockade of EGFR and c-Met abrogates redundant signaling and proliferation in head and neck carcinoma cells.

Xu H, Stabile LP, Gubish CT, Gooding WE, Grandis JR, Siegfried JM.

Clin Cancer Res. 2011 Jul 1;17(13):4425-38. doi: 10.1158/1078-0432.CCR-10-3339. Epub 2011 May 27.

PMID:
21622718
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

GIV/Girdin is a rheostat that fine-tunes growth factor signals during tumor progression.

Ghosh P, Garcia-Marcos M, Farquhar MG.

Cell Adh Migr. 2011 May-Jun;5(3):237-48. Epub 2011 May 1.

PMID:
21546796
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Enforced expression of miR-101 inhibits prostate cancer cell growth by modulating the COX-2 pathway in vivo.

Hao Y, Gu X, Zhao Y, Greene S, Sha W, Smoot DT, Califano J, Wu TC, Pang X.

Cancer Prev Res (Phila). 2011 Jul;4(7):1073-83. doi: 10.1158/1940-6207.CAPR-10-0333. Epub 2011 Mar 23.

PMID:
21430074
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

HGF-independent potentiation of EGFR action by c-Met.

Dulak AM, Gubish CT, Stabile LP, Henry C, Siegfried JM.

Oncogene. 2011 Aug 18;30(33):3625-35. doi: 10.1038/onc.2011.84. Epub 2011 Mar 21.

PMID:
21423210
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Overexpression of GPR39 contributes to malignant development of human esophageal squamous cell carcinoma.

Xie F, Liu H, Zhu YH, Qin YR, Dai Y, Zeng T, Chen L, Nie C, Tang H, Li Y, Fu L, Guan XY.

BMC Cancer. 2011 Feb 25;11:86. doi: 10.1186/1471-2407-11-86.

PMID:
21352519
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

NF-κB addiction and its role in cancer: 'one size does not fit all'.

Chaturvedi MM, Sung B, Yadav VR, Kannappan R, Aggarwal BB.

Oncogene. 2011 Apr 7;30(14):1615-30. doi: 10.1038/onc.2010.566. Epub 2010 Dec 20. Review.

PMID:
21170083
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Human β-defensin 3 promotes NF-κB-mediated CCR7 expression and anti-apoptotic signals in squamous cell carcinoma of the head and neck.

Mburu YK, Abe K, Ferris LK, Sarkar SN, Ferris RL.

Carcinogenesis. 2011 Feb;32(2):168-74. doi: 10.1093/carcin/bgq236. Epub 2010 Nov 11.

PMID:
21071608
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Tumor antigen-targeted, monoclonal antibody-based immunotherapy: clinical response, cellular immunity, and immunoescape.

Ferris RL, Jaffee EM, Ferrone S.

J Clin Oncol. 2010 Oct 1;28(28):4390-9. doi: 10.1200/JCO.2009.27.6360. Epub 2010 Aug 9. Review.

PMID:
20697078
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Quantitative proteomics analysis reveals molecular networks regulated by epidermal growth factor receptor level in head and neck cancer.

Yang W, Cai Q, Lui VW, Everley PA, Kim J, Bhola N, Quesnelle KM, Zetter BR, Steen H, Freeman MR, Grandis JR.

J Proteome Res. 2010 Jun 4;9(6):3073-82. doi: 10.1021/pr901211j.

PMID:
20426488
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Investigational EGFR-targeted therapy in head and neck squamous cell carcinoma.

Cassell A, Grandis JR.

Expert Opin Investig Drugs. 2010 Jun;19(6):709-22. doi: 10.1517/13543781003769844. Review.

PMID:
20415598
[PubMed - indexed for MEDLINE]
Free PMC Article

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