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Results: 1 to 20 of 25

1.

Memory CD8⁺ T cells can outsource IFN-γ production but not cytolytic killing for antiviral protection.

Remakus S, Rubio D, Lev A, Ma X, Fang M, Xu RH, Sigal LJ.

Cell Host Microbe. 2013 May 15;13(5):546-57. doi: 10.1016/j.chom.2013.04.004.

PMID:
23684306
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Immunodomination during peripheral vaccinia virus infection.

Lin LC, Flesch IE, Tscharke DC.

PLoS Pathog. 2013;9(4):e1003329. doi: 10.1371/journal.ppat.1003329. Epub 2013 Apr 25.

PMID:
23633956
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

The mature virion of ectromelia virus, a pathogenic poxvirus, is capable of intrahepatic spread and can serve as a target for delayed therapy.

Ma X, Xu RH, Roscoe F, Whitbeck JC, Eisenberg RJ, Cohen GH, Sigal LJ.

J Virol. 2013 Jun;87(12):7046-53. doi: 10.1128/JVI.03158-12. Epub 2013 Apr 17.

PMID:
23596297
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Characterization of ectromelia virus deficient in EVM036, the homolog of vaccinia virus F13L, and its application for rapid generation of recombinant viruses.

Roscoe F, Xu RH, Sigal LJ.

J Virol. 2012 Dec;86(24):13501-7. doi: 10.1128/JVI.01732-12. Epub 2012 Oct 3.

PMID:
23035222
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Memory CD8+ T cells specific for a single immunodominant or subdominant determinant induced by peptide-dendritic cell immunization protect from an acute lethal viral disease.

Remakus S, Rubio D, Ma X, Sette A, Sigal LJ.

J Virol. 2012 Sep;86(18):9748-59. doi: 10.1128/JVI.00981-12. Epub 2012 Jun 27.

PMID:
22740418
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Perforin-dependent CD4+ T-cell cytotoxicity contributes to control a murine poxvirus infection.

Fang M, Siciliano NA, Hersperger AR, Roscoe F, Hu A, Ma X, Shamsedeen AR, Eisenlohr LC, Sigal LJ.

Proc Natl Acad Sci U S A. 2012 Jun 19;109(25):9983-8. doi: 10.1073/pnas.1202143109. Epub 2012 Jun 4.

PMID:
22665800
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Comparable polyfunctionality of ectromelia virus- and vaccinia virus-specific murine T cells despite markedly different in vivo replication and pathogenicity.

Hersperger AR, Siciliano NA, Eisenlohr LC.

J Virol. 2012 Jul;86(13):7298-309. doi: 10.1128/JVI.00038-12. Epub 2012 Apr 24.

PMID:
22532670
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Antibody inhibition of a viral type 1 interferon decoy receptor cures a viral disease by restoring interferon signaling in the liver.

Xu RH, Rubio D, Roscoe F, Krouse TE, Truckenmiller ME, Norbury CC, Hudson PN, Damon IK, Alcamí A, Sigal LJ.

PLoS Pathog. 2012 Jan;8(1):e1002475. doi: 10.1371/journal.ppat.1002475. Epub 2012 Jan 5.

PMID:
22241999
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Multiple layers of CD80/86-dependent costimulatory activity regulate primary, memory, and secondary lymphocytic choriomeningitis virus-specific T cell immunity.

Eberlein J, Davenport B, Nguyen TT, Victorino F, Sparwasser T, Homann D.

J Virol. 2012 Feb;86(4):1955-70. doi: 10.1128/JVI.05949-11. Epub 2011 Dec 7.

PMID:
22156513
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

OX40:OX40L axis: emerging targets for improving poxvirus-based CD8(+) T-cell vaccines against respiratory viruses.

Goulding J, Tahiliani V, Salek-Ardakani S.

Immunol Rev. 2011 Nov;244(1):149-68. doi: 10.1111/j.1600-065X.2011.01062.x. Review.

PMID:
22017437
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Gamma interferon and perforin control the strength, but not the hierarchy, of immunodominance of an antiviral CD8+ T cell response.

Remakus S, Sigal LJ.

J Virol. 2011 Dec;85(23):12578-84. doi: 10.1128/JVI.05334-11. Epub 2011 Sep 14.

PMID:
21917955
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

CD94 is essential for NK cell-mediated resistance to a lethal viral disease.

Fang M, Orr MT, Spee P, Egebjerg T, Lanier LL, Sigal LJ.

Immunity. 2011 Apr 22;34(4):579-89. doi: 10.1016/j.immuni.2011.02.015.

PMID:
21439856
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

The TNFR family members OX40 and CD27 link viral virulence to protective T cell vaccines in mice.

Salek-Ardakani S, Flynn R, Arens R, Yagita H, Smith GL, Borst J, Schoenberger SP, Croft M.

J Clin Invest. 2011 Jan;121(1):296-307. doi: 10.1172/JCI42056. Epub 2010 Dec 22.

PMID:
21183789
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Induction of polyclonal CD8+ T cell activation and effector function by Pertussis toxin.

Murphey C, Chang S, Zhang X, Arulanandam B, Forsthuber TG.

Cell Immunol. 2011;267(1):50-5. doi: 10.1016/j.cellimm.2010.11.003. Epub 2010 Nov 13.

PMID:
21130421
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Differential requirements for CD80/86-CD28 costimulation in primary and memory CD4 T cell responses to vaccinia virus.

Fuse S, Tsai CY, Rommereim LM, Zhang W, Usherwood EJ.

Cell Immunol. 2011;266(2):130-4. doi: 10.1016/j.cellimm.2010.09.008. Epub 2010 Oct 30.

PMID:
21040905
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Age-dependent susceptibility to a viral disease due to decreased natural killer cell numbers and trafficking.

Fang M, Roscoe F, Sigal LJ.

J Exp Med. 2010 Oct 25;207(11):2369-81. doi: 10.1084/jem.20100282. Epub 2010 Sep 27.

PMID:
20876312
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Analysis of A47, an immunoprevalent protein of vaccinia virus, leads to a reevaluation of the total antiviral CD8+ T cell response.

Yuen TJ, Flesch IE, Hollett NA, Dobson BM, Russell TA, Fahrer AM, Tscharke DC.

J Virol. 2010 Oct;84(19):10220-9. doi: 10.1128/JVI.01281-10. Epub 2010 Jul 28.

PMID:
20668091
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Direct presentation is sufficient for an efficient anti-viral CD8+ T cell response.

Xu RH, Remakus S, Ma X, Roscoe F, Sigal LJ.

PLoS Pathog. 2010 Feb 12;6(2):e1000768. doi: 10.1371/journal.ppat.1000768.

PMID:
20169189
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Vaccinia virus A35R inhibits MHC class II antigen presentation.

Rehm KE, Connor RF, Jones GJ, Yimbu K, Roper RL.

Virology. 2010 Feb 5;397(1):176-86. doi: 10.1016/j.virol.2009.11.008. Epub 2009 Dec 2.

PMID:
19954808
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Distinct roles of CD28- and CD40 ligand-mediated costimulation in the development of protective immunity and pathology during Chlamydia muridarum urogenital infection in mice.

Chen L, Cheng W, Shivshankar P, Lei L, Zhang X, Wu Y, Yeh IT, Zhong G.

Infect Immun. 2009 Jul;77(7):3080-9. doi: 10.1128/IAI.00611-08. Epub 2009 Apr 27.

PMID:
19398542
[PubMed - indexed for MEDLINE]
Free PMC Article

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