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Items: 1 to 20 of 53


Regulation of fibroblast growth factor 15/19 and 21 on metabolism: in the fed or fasted state.

Guan D, Zhao L, Chen D, Yu B, Yu J.

J Transl Med. 2016 Mar 1;14(1):63. doi: 10.1186/s12967-016-0821-0.


Bile acid nuclear receptor FXR and digestive system diseases.

Ding L, Yang L, Wang Z, Huang W.

Acta Pharm Sin B. 2015 Mar;5(2):135-44. doi: 10.1016/j.apsb.2015.01.004. Epub 2015 Feb 25. Review.


Endocrine FGFs: Evolution, Physiology, Pathophysiology, and Pharmacotherapy.

Itoh N, Ohta H, Konishi M.

Front Endocrinol (Lausanne). 2015 Sep 29;6:154. doi: 10.3389/fendo.2015.00154. eCollection 2015. Review.


Expression of hepatic Fibroblast Growth Factor 19 is enhanced in Primary Biliary Cirrhosis and correlates with severity of the disease.

Wunsch E, Milkiewicz M, Wasik U, Trottier J, Kempińska-Podhorodecka A, Elias E, Barbier O, Milkiewicz P.

Sci Rep. 2015 Aug 21;5:13462. doi: 10.1038/srep13462.


FGF 19 and Bile Acids Increase Following Roux-en-Y Gastric Bypass but Not After Medical Management in Patients with Type 2 Diabetes.

Sachdev S, Wang Q, Billington C, Connett J, Ahmed L, Inabnet W, Chua S, Ikramuddin S, Korner J.

Obes Surg. 2016 May;26(5):957-65. doi: 10.1007/s11695-015-1834-0.


Bile Acids as Hormones: The FXR-FGF15/19 Pathway.

Kliewer SA, Mangelsdorf DJ.

Dig Dis. 2015;33(3):327-31. doi: 10.1159/000371670. Epub 2015 May 27. Review.


The Fibroblast Growth Factor signaling pathway.

Ornitz DM, Itoh N.

Wiley Interdiscip Rev Dev Biol. 2015 May-Jun;4(3):215-66. doi: 10.1002/wdev.176. Epub 2015 Mar 13. Review.


Impaired cholecystokinin-induced gallbladder emptying incriminated in spontaneous "black" pigment gallstone formation in germfree Swiss Webster mice.

Woods SE, Leonard MR, Hayden JA, Brophy MB, Bernert KR, Lavoie B, Muthupalani S, Whary MT, Mawe GM, Nolan EM, Carey MC, Fox JG.

Am J Physiol Gastrointest Liver Physiol. 2015 Feb 15;308(4):G335-49. doi: 10.1152/ajpgi.00314.2014. Epub 2014 Dec 4.


Tissue-specific actions of the metabolic hormones FGF15/19 and FGF21.

Owen BM, Mangelsdorf DJ, Kliewer SA.

Trends Endocrinol Metab. 2015 Jan;26(1):22-9. doi: 10.1016/j.tem.2014.10.002. Epub 2014 Dec 1. Review.


Impact of global Fxr deficiency on experimental acute pancreatitis and genetic variation in the FXR locus in human acute pancreatitis.

Nijmeijer RM, Schaap FG, Smits AJ, Kremer AE, Akkermans LM, Kroese AB, Rijkers GT, Schipper ME, Verheem A, Wijmenga C, Gooszen HG, van Erpecum KJ.

PLoS One. 2014 Dec 3;9(12):e114393. doi: 10.1371/journal.pone.0114393. eCollection 2014.


Upregulation of hepatic bile acid synthesis via fibroblast growth factor 19 is defective in gallstone disease but functional in overweight individuals.

Renner O, Harsch S, Matysik S, Lütjohann D, Schmitz G, Stange EF.

United European Gastroenterol J. 2014 Jun;2(3):216-25. doi: 10.1177/2050640614527938.


Antiinflammatory effect of phytosterols in experimental murine colitis model: prevention, induction, remission study.

Aldini R, Micucci M, Cevenini M, Fato R, Bergamini C, Nanni C, Cont M, Camborata C, Spinozzi S, Montagnani M, Roda G, D'Errico-Grigioni A, Rosini F, Roda A, Mazzella G, Chiarini A, Budriesi R.

PLoS One. 2014 Sep 30;9(9):e108112. doi: 10.1371/journal.pone.0108112. eCollection 2014.


Vitamin D deficiency promotes nonalcoholic steatohepatitis through impaired enterohepatic circulation in animal model.

Kong M, Zhu L, Bai L, Zhang X, Chen Y, Liu S, Zheng S, Pandol SJ, Han YP, Duan Z.

Am J Physiol Gastrointest Liver Physiol. 2014 Nov 1;307(9):G883-93. doi: 10.1152/ajpgi.00427.2013. Epub 2014 Sep 11.


Bile acid signaling in metabolic disease and drug therapy.

Li T, Chiang JY.

Pharmacol Rev. 2014 Oct;66(4):948-83. doi: 10.1124/pr.113.008201. Review.


Decreased bile-acid synthesis in livers of hepatocyte-conditional NADPH-cytochrome P450 reductase-null mice results in increased bile acids in serum.

Cheng X, Zhang Y, Klaassen CD.

J Pharmacol Exp Ther. 2014 Oct;351(1):105-13. doi: 10.1124/jpet.114.216796. Epub 2014 Jul 17.


Regulation of bile acid homeostasis by the intestinal Diet1-FGF15/19 axis.

Reue K, Lee JM, Vergnes L.

Curr Opin Lipidol. 2014 Apr;25(2):140-7. doi: 10.1097/MOL.0000000000000060. Review.


Enterohepatic bacterial infections dysregulate the FGF15-FGFR4 endocrine axis.

Romain G, Tremblay S, Arena ET, Antunes LC, Covey S, Chow MT, Finlay BB, Menendez A.

BMC Microbiol. 2013 Oct 29;13:238. doi: 10.1186/1471-2180-13-238.


Peripheral reduction of FGFR4 with antisense oligonucleotides increases metabolic rate and lowers adiposity in diet-induced obese mice.

Yu XX, Watts LM, Manchem VP, Chakravarty K, Monia BP, McCaleb ML, Bhanot S.

PLoS One. 2013 Jul 29;8(7):e66923. doi: 10.1371/journal.pone.0066923. Print 2013.


Pleiotropic roles of bile acids in metabolism.

de Aguiar Vallim TQ, Tarling EJ, Edwards PA.

Cell Metab. 2013 May 7;17(5):657-69. doi: 10.1016/j.cmet.2013.03.013. Epub 2013 Apr 18. Review.


Nuclear receptors as drug targets in cholestatic liver diseases.

Halilbasic E, Baghdasaryan A, Trauner M.

Clin Liver Dis. 2013 May;17(2):161-89. doi: 10.1016/j.cld.2012.12.001. Review.

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