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Items: 1 to 20 of 21

1.

Modified vaccinia virus Ankara triggers type I IFN production in murine conventional dendritic cells via a cGAS/STING-mediated cytosolic DNA-sensing pathway.

Dai P, Wang W, Cao H, Avogadri F, Dai L, Drexler I, Joyce JA, Li XD, Chen Z, Merghoub T, Shuman S, Deng L.

PLoS Pathog. 2014 Apr 17;10(4):e1003989. doi: 10.1371/journal.ppat.1003989. eCollection 2014 Apr.

2.

Differential induction of apoptosis, interferon signaling, and phagocytosis in macrophages infected with a panel of attenuated and nonattenuated poxviruses.

Royo S, Sainz B Jr, Hernández-Jiménez E, Reyburn H, López-Collazo E, Guerra S.

J Virol. 2014 May;88(10):5511-23. doi: 10.1128/JVI.00468-14. Epub 2014 Mar 5. Erratum in: J Virol. 2016 Jun 1;90(11):5530-1.

3.

A novel role for the apoptosis inhibitor ARC in suppressing TNFα-induced regulated necrosis.

Kung G, Dai P, Deng L, Kitsis RN.

Cell Death Differ. 2014 Apr;21(4):634-44. doi: 10.1038/cdd.2013.195. Epub 2014 Jan 17.

4.

ISG15 is counteracted by vaccinia virus E3 protein and controls the proinflammatory response against viral infection.

Eduardo-Correia B, Martínez-Romero C, García-Sastre A, Guerra S.

J Virol. 2014 Feb;88(4):2312-8. doi: 10.1128/JVI.03293-13. Epub 2013 Nov 20.

5.

Perinatal exposure to environmental tobacco smoke (ETS) enhances susceptibility to viral and secondary bacterial infections.

Claude JA, Grimm A, Savage HP, Pinkerton KE.

Int J Environ Res Public Health. 2012 Oct 31;9(11):3954-64. doi: 10.3390/ijerph9113954.

6.

Innate immune response of human plasmacytoid dendritic cells to poxvirus infection is subverted by vaccinia E3 via its Z-DNA/RNA binding domain.

Cao H, Dai P, Wang W, Li H, Yuan J, Wang F, Fang CM, Pitha PM, Liu J, Condit RC, McFadden G, Merghoub T, Houghton AN, Young JW, Shuman S, Deng L.

PLoS One. 2012;7(5):e36823. doi: 10.1371/journal.pone.0036823. Epub 2012 May 14.

7.

Host-range restriction of vaccinia virus E3L deletion mutant can be overcome in vitro, but not in vivo, by expression of the influenza virus NS1 protein.

Guerra S, Abaitua F, Martínez-Sobrido L, Esteban M, García-Sastre A, Rodríguez D.

PLoS One. 2011;6(12):e28677. doi: 10.1371/journal.pone.0028677. Epub 2011 Dec 13.

8.

Comparative analysis of poxvirus orthologues of the vaccinia virus E3 protein: modulation of protein kinase R activity, cytokine responses, and virus pathogenicity.

Myskiw C, Arsenio J, Hammett C, van Bruggen R, Deschambault Y, Beausoleil N, Babiuk S, Cao J.

J Virol. 2011 Dec;85(23):12280-91. doi: 10.1128/JVI.05505-11. Epub 2011 Sep 14.

9.

Myxoma virus induces type I interferon production in murine plasmacytoid dendritic cells via a TLR9/MyD88-, IRF5/IRF7-, and IFNAR-dependent pathway.

Dai P, Cao H, Merghoub T, Avogadri F, Wang W, Parikh T, Fang CM, Pitha PM, Fitzgerald KA, Rahman MM, McFadden G, Hu X, Houghton AN, Shuman S, Deng L.

J Virol. 2011 Oct;85(20):10814-25. doi: 10.1128/JVI.00104-11. Epub 2011 Aug 10. Erratum in: J Virol. 2011 Dec;85(23):12835.

10.

Cowpox virus induces interleukin-10 both in vitro and in vivo.

Spesock AH, Barefoot BE, Ray CA, Kenan DJ, Gunn MD, Ramsburg EA, Pickup DJ.

Virology. 2011 Aug 15;417(1):87-97. doi: 10.1016/j.virol.2011.05.010. Epub 2011 Jun 11.

11.

Cowpox virus inhibits human dendritic cell immune function by nonlethal, nonproductive infection.

Hansen SJ, Rushton J, Dekonenko A, Chand HS, Olson GK, Hutt JA, Pickup D, Lyons CR, Lipscomb MF.

Virology. 2011 Apr 10;412(2):411-25. doi: 10.1016/j.virol.2011.01.024. Epub 2011 Feb 21.

12.

Function and regulation of retinoic acid-inducible gene-I.

Matsumiya T, Stafforini DM.

Crit Rev Immunol. 2010;30(6):489-513. Review.

13.

Vaccinia virus A35R inhibits MHC class II antigen presentation.

Rehm KE, Connor RF, Jones GJ, Yimbu K, Roper RL.

Virology. 2010 Feb 5;397(1):176-86. doi: 10.1016/j.virol.2009.11.008. Epub 2009 Dec 2.

14.

DNA-triggered innate immune responses are propagated by gap junction communication.

Patel SJ, King KR, Casali M, Yarmush ML.

Proc Natl Acad Sci U S A. 2009 Aug 4;106(31):12867-72. doi: 10.1073/pnas.0809292106. Epub 2009 Jul 17.

15.

Modified vaccinia virus Ankara can activate NF-kappaB transcription factors through a double-stranded RNA-activated protein kinase (PKR)-dependent pathway during the early phase of virus replication.

Lynch HE, Ray CA, Oie KL, Pollara JJ, Petty IT, Sadler AJ, Williams BR, Pickup DJ.

Virology. 2009 Sep 1;391(2):177-86. doi: 10.1016/j.virol.2009.06.012.

16.

Vaccinia virus E3 suppresses expression of diverse cytokines through inhibition of the PKR, NF-kappaB, and IRF3 pathways.

Myskiw C, Arsenio J, van Bruggen R, Deschambault Y, Cao J.

J Virol. 2009 Jul;83(13):6757-68. doi: 10.1128/JVI.02570-08. Epub 2009 Apr 15.

17.

Vaccinia virus subverts a mitochondrial antiviral signaling protein-dependent innate immune response in keratinocytes through its double-stranded RNA binding protein, E3.

Deng L, Dai P, Parikh T, Cao H, Bhoj V, Sun Q, Chen Z, Merghoub T, Houghton A, Shuman S.

J Virol. 2008 Nov;82(21):10735-46. doi: 10.1128/JVI.01305-08. Epub 2008 Aug 20.

18.

Vaccinia virus E3 protein prevents the antiviral action of ISG15.

Guerra S, Cáceres A, Knobeloch KP, Horak I, Esteban M.

PLoS Pathog. 2008 Jul 4;4(7):e1000096. doi: 10.1371/journal.ppat.1000096.

19.

Vaccinia virus infection modulates the hematopoietic cell compartments in the bone marrow.

Singh P, Yao Y, Weliver A, Broxmeyer HE, Hong SC, Chang CH.

Stem Cells. 2008 Apr;26(4):1009-16. doi: 10.1634/stemcells.2007-0461. Epub 2008 Feb 7.

20.

Identification of novel antipoxviral agents: mitoxantrone inhibits vaccinia virus replication by blocking virion assembly.

Deng L, Dai P, Ciro A, Smee DF, Djaballah H, Shuman S.

J Virol. 2007 Dec;81(24):13392-402. Epub 2007 Oct 10.

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