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Items: 15


CD4+ T Cells Targeting Dominant and Cryptic Epitopes from Bacillus anthracis Lethal Factor.

Ascough S, Ingram RJ, Chu KK, Musson JA, Moore SJ, Gallagher T, Baillie L, Williamson ED, Robinson JH, Maillere B, Boyton RJ, Altmann DM.

Front Microbiol. 2016 Jan 5;6:1506. doi: 10.3389/fmicb.2015.01506. eCollection 2015.


Fold stability during endolysosomal acidification is a key factor for allergenicity and immunogenicity of the major birch pollen allergen.

Machado Y, Freier R, Scheiblhofer S, Thalhamer T, Mayr M, Briza P, Grutsch S, Ahammer L, Fuchs JE, Wallnoefer HG, Isakovic A, Kohlbauer V, Hinterholzer A, Steiner M, Danzer M, Horejs-Hoeck J, Ferreira F, Liedl KR, Tollinger M, Lackner P, Johnson CM, Brandstetter H, Thalhamer J, Weiss R.

J Allergy Clin Immunol. 2016 May;137(5):1525-34. doi: 10.1016/j.jaci.2015.09.026. Epub 2015 Nov 11.


Conformational instability governed by disulfide bonds partitions the dominant from subdominant helper T-cell responses specific for HIV-1 envelope glycoprotein gp120.

Nguyen HN, Steede NK, Robinson JE, Landry SJ.

Vaccine. 2015 Jun 9;33(25):2887-96. doi: 10.1016/j.vaccine.2015.04.082. Epub 2015 May 2.


Specificities of human CD4+ T cell responses to an inactivated flavivirus vaccine and infection: correlation with structure and epitope prediction.

Schwaiger J, Aberle JH, Stiasny K, Knapp B, Schreiner W, Fae I, Fischer G, Scheinost O, Chmelik V, Heinz FX.

J Virol. 2014 Jul;88(14):7828-42. doi: 10.1128/JVI.00196-14. Epub 2014 Apr 30.


Influence of high hydrostatic pressure on epitope mapping of tobacco mosaic virus coat protein.

Ferreira de Lima Neto D, Bonafe CF, Arns CW.

Viral Immunol. 2014 Mar;27(2):60-74. doi: 10.1089/vim.2013.0088.


The control of the specificity of CD4 T cell responses: thresholds, breakpoints, and ceilings.

Sant AJ, Chaves FA, Leddon SA, Tung J.

Front Immunol. 2013 Oct 23;4:340. doi: 10.3389/fimmu.2013.00340. Review.


PREDIVAC: CD4+ T-cell epitope prediction for vaccine design that covers 95% of HLA class II DR protein diversity.

Oyarzún P, Ellis JJ, Bodén M, Kobe B.

BMC Bioinformatics. 2013 Feb 14;14:52. doi: 10.1186/1471-2105-14-52.


Assessing protein immunogenicity with a dendritic cell line-derived endolysosomal degradome.

Egger M, Jürets A, Wallner M, Briza P, Ruzek S, Hainzl S, Pichler U, Kitzmüller C, Bohle B, Huber CG, Ferreira F.

PLoS One. 2011 Feb 16;6(2):e17278. doi: 10.1371/journal.pone.0017278.


Structural properties of MHC class II ligands, implications for the prediction of MHC class II epitopes.

Jørgensen KW, Buus S, Nielsen M.

PLoS One. 2010 Dec 30;5(12):e15877. doi: 10.1371/journal.pone.0015877.


Influence of disulfide-stabilized structure on the specificity of helper T-cell and antibody responses to HIV envelope glycoprotein gp120.

Mirano-Bascos D, Steede NK, Robinson JE, Landry SJ.

J Virol. 2010 Apr;84(7):3303-11. doi: 10.1128/JVI.02242-09. Epub 2010 Jan 20.


Lymphocytic choriomeningitis virus infection yields overlapping CD4+ and CD8+ T-cell responses.

Dow C, Oseroff C, Peters B, Nance-Sotelo C, Sidney J, Buchmeier M, Sette A, Mothé BR.

J Virol. 2008 Dec;82(23):11734-41. doi: 10.1128/JVI.00435-08. Epub 2008 Oct 1.


Immunodominance of CD4 T cells to foreign antigens is peptide intrinsic and independent of molecular context: implications for vaccine design.

Weaver JM, Lazarski CA, Richards KA, Chaves FA, Jenks SA, Menges PR, Sant AJ.

J Immunol. 2008 Sep 1;181(5):3039-48.


Antigen structure influences helper T-cell epitope dominance in the human immune response to HIV envelope glycoprotein gp120.

Mirano-Bascos D, Tary-Lehmann M, Landry SJ.

Eur J Immunol. 2008 May;38(5):1231-7. doi: 10.1002/eji.200738011.

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