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Synergism between the mTOR inhibitor rapamycin and FAK down-regulation in the treatment of acute lymphoblastic leukemia.

Shi PJ, Xu LH, Lin KY, Weng WJ, Fang JP.

J Hematol Oncol. 2016 Feb 18;9:12. doi: 10.1186/s13045-016-0241-x.


David and Goliath: chemical perturbation of eukaryotes by bacteria.

Ho LK, Nodwell JR.

J Ind Microbiol Biotechnol. 2016 Mar;43(2-3):233-48. doi: 10.1007/s10295-015-1686-6. Epub 2015 Oct 3.


A randomized phase II trial of tacrolimus, mycophenolate mofetil and sirolimus after non-myeloablative unrelated donor transplantation.

Kornblit B, Maloney DG, Storer BE, Maris MB, Vindeløv L, Hari P, Langston AA, Pulsipher MA, Bethge WA, Chauncey TR, Lange T, Petersen FB, Hübel K, Woolfrey AE, Flowers ME, Storb R, Sandmaier BM.

Haematologica. 2014 Oct;99(10):1624-31. doi: 10.3324/haematol.2014.108340. Epub 2014 Aug 1.


Rapamycin rescues the poor developmental capacity of aged porcine oocytes.

Lee SE, Kim EY, Choi HY, Moon JJ, Park MJ, Lee JB, Jeong CJ, Park SP.

Asian-Australas J Anim Sci. 2014 May;27(5):635-47. doi: 10.5713/ajas.2013.13816.


Insight into the role of mTOR and metabolism in T cells reveals new potential approaches to preventing graft rejection.

Lo YC, Lee CF, Powell JD.

Curr Opin Organ Transplant. 2014 Aug;19(4):363-71. doi: 10.1097/MOT.0000000000000098. Review.


What is left when anti-tumour necrosis factor therapy in inflammatory bowel diseases fails?

Lawrance IC.

World J Gastroenterol. 2014 Feb 7;20(5):1248-58. doi: 10.3748/wjg.v20.i5.1248. Review.


Treating metastatic soft-tissue or bone sarcomas - potential role of ridaforolimus.

Keedy VL.

Onco Targets Ther. 2012;5:153-60. doi: 10.2147/OTT.S19055. Epub 2012 Aug 22.


The role and regulation of mTOR in T-lymphocyte function.

O'Brien TF, Zhong XP.

Arch Immunol Ther Exp (Warsz). 2012 Jun;60(3):173-81. doi: 10.1007/s00005-012-0171-4. Epub 2012 Apr 8. Review.


Should diabetic women with breast cancer have their own intervention studies?

Potter DA, Yee D, Guo Z, Rodriguez M.

Endocr Relat Cancer. 2012 Feb 13;19(1):C13-7. doi: 10.1530/ERC-11-0309. Print 2012 Feb.


Modulation of T cell proliferation and cytokine response by Plumbagin, extracted from Plumbago zeylanica in collagen induced arthritis.

Poosarla A, D N R, Athota RR, Sunkara VG.

BMC Complement Altern Med. 2011 Nov 16;11:114. doi: 10.1186/1472-6882-11-114.


Rapamycin attenuates airway hyperreactivity, goblet cells, and IgE in experimental allergic asthma.

Mushaben EM, Kramer EL, Brandt EB, Khurana Hershey GK, Le Cras TD.

J Immunol. 2011 Dec 1;187(11):5756-63. doi: 10.4049/jimmunol.1102133. Epub 2011 Oct 21.


BCR-ABL suppresses autophagy through ATF5-mediated regulation of mTOR transcription.

Sheng Z, Ma L, Sun JE, Zhu LJ, Green MR.

Blood. 2011 Sep 8;118(10):2840-8. doi: 10.1182/blood-2010-12-322537. Epub 2011 Jun 29.


Expression, localisation and functional activation of NFAT-2 in normal human skin, psoriasis, and cultured keratocytes.

Al-Daraji WI, Malak TT, Prescott RJ, Abdellaoui A, Ali MM, Dabash T, Zelger BG, Zelger B.

Int J Clin Exp Med. 2009 Jun 18;2(2):176-92.


Population pharmacokinetics of sirolimus in de novo Chinese adult renal transplant patients.

Jiao Z, Shi XJ, Li ZD, Zhong MK.

Br J Clin Pharmacol. 2009 Jul;68(1):47-60. doi: 10.1111/j.1365-2125.2009.03392.x.


Sirolimus in combination with cyclosporine or tacrolimus plus methotrexate for prevention of graft-versus-host disease following hematopoietic cell transplantation from unrelated donors.

Furlong T, Kiem HP, Appelbaum FR, Carpenter PA, Deeg HJ, Doney K, Flowers ME, Mielcarek M, Nash RA, Storb R, Martin PJ.

Biol Blood Marrow Transplant. 2008 May;14(5):531-7. doi: 10.1016/j.bbmt.2008.02.009.


The proline-rich Akt substrate of 40 kDa (PRAS40) is a physiological substrate of mammalian target of rapamycin complex 1.

Oshiro N, Takahashi R, Yoshino K, Tanimura K, Nakashima A, Eguchi S, Miyamoto T, Hara K, Takehana K, Avruch J, Kikkawa U, Yonezawa K.

J Biol Chem. 2007 Jul 13;282(28):20329-39. Epub 2007 May 21.

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