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Cited In for PubMed (Select 16885348)


High EGFR_1 Inside-Out Activated Inflammation-Induced Motility through SLC2A1-CCNB2-HMMR-KIF11-NUSAP1-PRC1-UBE2C.

Zhou H, Wang L, Huang J, Jiang M, Zhang X, Zhang L, Wang Y, Jiang Z, Zhang Z.

J Cancer. 2015 Apr 5;6(6):519-24. doi: 10.7150/jca.11404. eCollection 2015.


Cyclin-dependent kinase 5 acts as a critical determinant of AKT-dependent proliferation and regulates differential gene expression by the androgen receptor in prostate cancer cells.

Lindqvist J, Imanishi SY, Torvaldson E, Malinen M, Remes M, Örn F, Palvimo JJ, Eriksson JE.

Mol Biol Cell. 2015 Jun 1;26(11):1971-84. doi: 10.1091/mbc.E14-12-1634. Epub 2015 Apr 7.


Targeting cyclin-dependent kinases in human cancers: from small molecules to Peptide inhibitors.

Peyressatre M, Prével C, Pellerano M, Morris MC.

Cancers (Basel). 2015 Jan 23;7(1):179-237. doi: 10.3390/cancers7010179. Review.


Proteomic analysis of the human cyclin-dependent kinase family reveals a novel CDK5 complex involved in cell growth and migration.

Xu S, Li X, Gong Z, Wang W, Li Y, Nair BC, Piao H, Yang K, Wu G, Chen J.

Mol Cell Proteomics. 2014 Nov;13(11):2986-3000. doi: 10.1074/mcp.M113.036699. Epub 2014 Aug 5.


Contribution of nestin positive esophageal squamous cancer cells on malignant proliferation, apoptosis, and poor prognosis.

Zhong B, Wang T, Lun X, Zhang J, Zheng S, Yang W, Li W, Xiang AP, Chen Z.

Cancer Cell Int. 2014 Jun 20;14:57. doi: 10.1186/1475-2867-14-57. eCollection 2014.


Small-molecule screening of PC3 prostate cancer cells identifies tilorone dihydrochloride to selectively inhibit cell growth based on cyclin-dependent kinase 5 expression.

Wissing MD, Dadon T, Kim E, Piontek KB, Shim JS, Kaelber NS, Liu JO, Kachhap SK, Nelkin BD.

Oncol Rep. 2014 Jul;32(1):419-24. doi: 10.3892/or.2014.3174. Epub 2014 May 13.


Talin1 phosphorylation activates β1 integrins: a novel mechanism to promote prostate cancer bone metastasis.

Jin JK, Tien PC, Cheng CJ, Song JH, Huang C, Lin SH, Gallick GE.

Oncogene. 2015 Apr 2;34(14):1811-21. doi: 10.1038/onc.2014.116. Epub 2014 May 5.


Role of CDK5/cyclin complexes in ischemia-induced death and survival of renal tubular cells.

Guevara T, Sancho M, Pérez-Payá E, Orzáez M.

Cell Cycle. 2014;13(10):1617-26. doi: 10.4161/cc.28628. Epub 2014 Mar 25.


The role of Cdk5 in neuroendocrine thyroid cancer.

Pozo K, Castro-Rivera E, Tan C, Plattner F, Schwach G, Siegl V, Meyer D, Guo A, Gundara J, Mettlach G, Richer E, Guevara JA, Ning L, Gupta A, Hao G, Tsai LH, Sun X, Antich P, Sidhu S, Robinson BG, Chen H, Nwariaku FE, Pfragner R, Richardson JA, Bibb JA.

Cancer Cell. 2013 Oct 14;24(4):499-511. doi: 10.1016/j.ccr.2013.08.027.


CDK5 is essential for TGF-β1-induced epithelial-mesenchymal transition and breast cancer progression.

Liang Q, Li L, Zhang J, Lei Y, Wang L, Liu DX, Feng J, Hou P, Yao R, Zhang Y, Huang B, Lu J.

Sci Rep. 2013 Oct 14;3:2932. doi: 10.1038/srep02932.


Klf4 is a transcriptional regulator of genes critical for EMT, including Jnk1 (Mapk8).

Tiwari N, Meyer-Schaller N, Arnold P, Antoniadis H, Pachkov M, van Nimwegen E, Christofori G.

PLoS One. 2013;8(2):e57329. doi: 10.1371/journal.pone.0057329. Epub 2013 Feb 25. Erratum in: PLoS One. 2013;8(10). doi:10.1371/annotation/121b04a1-0cbb-4e24-8a63-fc9cdd31ec76.


Re-thinking cell cycle regulators: the cross-talk with metabolism.

Fajas L.

Front Oncol. 2013 Jan 24;3:4. doi: 10.3389/fonc.2013.00004. eCollection 2013.


Trisubstituted pyrazolopyrimidines as novel angiogenesis inhibitors.

Weitensteiner SB, Liebl J, Krystof V, Havlíček L, Gucký T, Strnad M, Fürst R, Vollmar AM, Zahler S.

PLoS One. 2013;8(1):e54607. doi: 10.1371/journal.pone.0054607. Epub 2013 Jan 15.


Retinoic Acid Induces Apoptosis of Prostate Cancer DU145 Cells through Cdk5 Overactivation.

Chen MC, Huang CY, Hsu SL, Lin E, Ku CT, Lin H, Chen CM.

Evid Based Complement Alternat Med. 2012;2012:580736. doi: 10.1155/2012/580736. Epub 2012 Dec 13.


Level of cdk5 expression predicts the survival of relapsed multiple myeloma patients.

Levacque Z, Rosales JL, Lee KY.

Cell Cycle. 2012 Nov 1;11(21):4093-5. doi: 10.4161/cc.21886. Epub 2012 Sep 17. No abstract available.


Phosphoregulation of the RNA-binding protein Hu antigen R (HuR) by Cdk5 affects centrosome function.

Filippova N, Yang X, King P, Nabors LB.

J Biol Chem. 2012 Sep 14;287(38):32277-87. doi: 10.1074/jbc.M112.353912. Epub 2012 Jul 24.


Achaete-scute homologue-1 (ASH1) stimulates migration of lung cancer cells through Cdk5/p35 pathway.

Demelash A, Rudrabhatla P, Pant HC, Wang X, Amin ND, McWhite CD, Naizhen X, Linnoila RI.

Mol Biol Cell. 2012 Aug;23(15):2856-66. doi: 10.1091/mbc.E10-12-1010. Epub 2012 Jun 13.


Cell adhesion and its endocytic regulation in cell migration during neural development and cancer metastasis.

Kawauchi T.

Int J Mol Sci. 2012;13(4):4564-90. doi: 10.3390/ijms13044564. Epub 2012 Apr 11.


Identification of unique MEK-dependent genes in GNAQ mutant uveal melanoma involved in cell growth, tumor cell invasion, and MEK resistance.

Ambrosini G, Pratilas CA, Qin LX, Tadi M, Surriga O, Carvajal RD, Schwartz GK.

Clin Cancer Res. 2012 Jul 1;18(13):3552-61. doi: 10.1158/1078-0432.CCR-11-3086. Epub 2012 May 1.


Computational identification and modeling of crosstalk between phosphorylation, O-β-glycosylation and methylation of FoxO3 and implications for cancer therapeutics.

Butt AM, Feng D, Idrees M, Tong Y, Lu J.

Int J Mol Sci. 2012;13(3):2918-38. doi: 10.3390/ijms13032918. Epub 2012 Mar 5.

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