Items per page
Sort by

Send to:

Choose Destination

Links from PubMed

Items: 1 to 20 of 31


FoxM1 Drives a Feed-Forward STAT3-Activation Signaling Loop That Promotes the Self-Renewal and Tumorigenicity of Glioblastoma Stem-like Cells.

Gong AH, Wei P, Zhang S, Yao J, Yuan Y, Zhou AD, Lang FF, Heimberger AB, Rao G, Huang S.

Cancer Res. 2015 Jun 1;75(11):2337-48. doi: 10.1158/0008-5472.CAN-14-2800. Epub 2015 Apr 1.


Targeted Blockade of JAK/STAT3 Signaling Inhibits Ovarian Carcinoma Growth.

Gritsina G, Xiao F, O'Brien SW, Gabbasov R, Maglaty MA, Xu RH, Thapa RJ, Zhou Y, Nicolas E, Litwin S, Balachandran S, Sigal LJ, Huszar D, Connolly DC.

Mol Cancer Ther. 2015 Apr;14(4):1035-47. doi: 10.1158/1535-7163.MCT-14-0800. Epub 2015 Feb 2.


Gene expression regulation by agonist-independent constitutive signaling of melanocortin-1 receptor.

Seong I, Kim J.

Endocrinol Metab (Seoul). 2014 Jun;29(2):179-84. doi: 10.3803/EnM.2014.29.2.179. Epub 2014 Jun 26.


The Role of STAT3 in Thyroid Cancer.

Sosonkina N, Starenki D, Park JI.

Cancers (Basel). 2014 Mar 6;6(1):526-44. doi: 10.3390/cancers6010526.


Raf kinase inhibitor protein (RKIP) blocks signal transducer and activator of transcription 3 (STAT3) activation in breast and prostate cancer.

Yousuf S, Duan M, Moen EL, Cross-Knorr S, Brilliant K, Bonavida B, LaValle T, Yeung KC, Al-Mulla F, Chin E, Chatterjee D.

PLoS One. 2014 Mar 21;9(3):e92478. doi: 10.1371/journal.pone.0092478. eCollection 2014.


MLS-2384, a new 6-bromoindirubin derivative with dual JAK/Src kinase inhibitory activity, suppresses growth of diverse cancer cells.

Liu L, Gaboriaud N, Vougogianopoulou K, Tian Y, Wu J, Wen W, Skaltsounis L, Jove R.

Cancer Biol Ther. 2014 Feb;15(2):178-84. doi: 10.4161/cbt.26721. Epub 2013 Nov 1.


Brk/PTK6 cooperates with HER2 and Src in regulating breast cancer cell survival and epithelial-to-mesenchymal transition.

Ai M, Liang K, Lu Y, Qiu S, Fan Z.

Cancer Biol Ther. 2013 Mar;14(3):237-45. doi: 10.4161/cbt.23295. Epub 2013 Jan 4.


Dual oxidase-1 is required for airway epithelial cell migration and bronchiolar reepithelialization after injury.

Gorissen SH, Hristova M, Habibovic A, Sipsey LM, Spiess PC, Janssen-Heininger YM, van der Vliet A.

Am J Respir Cell Mol Biol. 2013 Mar;48(3):337-45. doi: 10.1165/rcmb.2012-0393OC. Epub 2012 Dec 13.


Spirooxindole derivative SOID-8 induces apoptosis associated with inhibition of JAK2/STAT3 signaling in melanoma cells.

Tian Y, Nam S, Liu L, Yakushijin F, Yakushijin K, Buettner R, Liang W, Yang F, Ma Y, Horne D, Jove R.

PLoS One. 2012;7(11):e49306. doi: 10.1371/journal.pone.0049306. Epub 2012 Nov 16.


A novel 7-bromoindirubin with potent anticancer activity suppresses survival of human melanoma cells associated with inhibition of STAT3 and Akt signaling.

Liu L, Kritsanida M, Magiatis P, Gaboriaud N, Wang Y, Wu J, Buettner R, Yang F, Nam S, Skaltsounis L, Jove R.

Cancer Biol Ther. 2012 Nov;13(13):1255-61. doi: 10.4161/cbt.21781. Epub 2012 Aug 16.


STAT3 protein interacts with Class O Forkhead transcription factors in the cytoplasm and regulates nuclear/cytoplasmic localization of FoxO1 and FoxO3a proteins in CD4(+) T cells.

Oh HM, Yu CR, Dambuza I, Marrero B, Egwuagu CE.

J Biol Chem. 2012 Aug 31;287(36):30436-43. doi: 10.1074/jbc.M112.359661. Epub 2012 Jul 2.


First-in-human trial of a STAT3 decoy oligonucleotide in head and neck tumors: implications for cancer therapy.

Sen M, Thomas SM, Kim S, Yeh JI, Ferris RL, Johnson JT, Duvvuri U, Lee J, Sahu N, Joyce S, Freilino ML, Shi H, Li C, Ly D, Rapireddy S, Etter JP, Li PK, Wang L, Chiosea S, Seethala RR, Gooding WE, Chen X, Kaminski N, Pandit K, Johnson DE, Grandis JR.

Cancer Discov. 2012 Aug;2(8):694-705. doi: 10.1158/2159-8290.CD-12-0191. Epub 2012 Jun 20.


The Jak/STAT pathway is involved in synaptic plasticity.

Nicolas CS, Peineau S, Amici M, Csaba Z, Fafouri A, Javalet C, Collett VJ, Hildebrandt L, Seaton G, Choi SL, Sim SE, Bradley C, Lee K, Zhuo M, Kaang BK, Gressens P, Dournaud P, Fitzjohn SM, Bortolotto ZA, Cho K, Collingridge GL.

Neuron. 2012 Jan 26;73(2):374-90. doi: 10.1016/j.neuron.2011.11.024.


Necdin, a negative growth regulator, is a novel STAT3 target gene down-regulated in human cancer.

Haviland R, Eschrich S, Bloom G, Ma Y, Minton S, Jove R, Cress WD.

PLoS One. 2011;6(10):e24923. doi: 10.1371/journal.pone.0024923. Epub 2011 Oct 27.


6-Bromoindirubin-3'-oxime inhibits JAK/STAT3 signaling and induces apoptosis of human melanoma cells.

Liu L, Nam S, Tian Y, Yang F, Wu J, Wang Y, Scuto A, Polychronopoulos P, Magiatis P, Skaltsounis L, Jove R.

Cancer Res. 2011 Jun 1;71(11):3972-9. doi: 10.1158/0008-5472.CAN-10-3852. Epub 2011 May 24.


HGF/c-met/Stat3 signaling during skin tumor cell invasion: indications for a positive feedback loop.

Syed ZA, Yin W, Hughes K, Gill JN, Shi R, Clifford JL.

BMC Cancer. 2011 May 19;11:180. doi: 10.1186/1471-2407-11-180.


IL-6 induced STAT3 signalling is associated with the proliferation of human muscle satellite cells following acute muscle damage.

Toth KG, McKay BR, De Lisio M, Little JP, Tarnopolsky MA, Parise G.

PLoS One. 2011 Mar 9;6(3):e17392. doi: 10.1371/journal.pone.0017392.


γ-Tocotrienol is a novel inhibitor of constitutive and inducible STAT3 signalling pathway in human hepatocellular carcinoma: potential role as an antiproliferative, pro-apoptotic and chemosensitizing agent.

Rajendran P, Li F, Manu KA, Shanmugam MK, Loo SY, Kumar AP, Sethi G.

Br J Pharmacol. 2011 May;163(2):283-98. doi: 10.1111/j.1476-5381.2010.01187.x.


p53 regulation of podosome formation and cellular invasion in vascular smooth muscle cells.

Mak AS.

Cell Adh Migr. 2011 Mar-Apr;5(2):144-9. Epub 2011 Mar 1. Review.

Items per page
Sort by

Send to:

Choose Destination

Supplemental Content

Write to the Help Desk