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Results: 1 to 20 of 41

Cited In for PubMed (Select 16801682)


The Amyloid Precursor Protein Controls PIKfyve Function.

Balklava Z, Niehage C, Currinn H, Mellor L, Guscott B, Poulin G, Hoflack B, Wassmer T.

PLoS One. 2015 Jun 30;10(6):e0130485. doi: 10.1371/journal.pone.0130485. eCollection 2015.


The Fab1/PIKfyve phosphoinositide phosphate kinase is not necessary to maintain the pH of lysosomes and of the yeast vacuole.

Ho CY, Choy CH, Wattson CA, Johnson DE, Botelho RJ.

J Biol Chem. 2015 Apr 10;290(15):9919-28. doi: 10.1074/jbc.M114.613984. Epub 2015 Feb 20.


Lipid kinases are essential for apicoplast homeostasis in Toxoplasma gondii.

Daher W, Morlon-Guyot J, Sheiner L, Lentini G, Berry L, Tawk L, Dubremetz JF, Wengelnik K, Striepen B, Lebrun M.

Cell Microbiol. 2015 Apr;17(4):559-78. doi: 10.1111/cmi.12383. Epub 2014 Nov 22.


Loss of the Sec1/Munc18-family proteins VPS-33.2 and VPS-33.1 bypasses a block in endosome maturation in Caenorhabditis elegans.

Solinger JA, Spang A.

Mol Biol Cell. 2014 Dec 1;25(24):3909-25. doi: 10.1091/mbc.E13-12-0710. Epub 2014 Oct 1.


C. elegans as a model for membrane traffic.

Sato K, Norris A, Sato M, Grant BD.

WormBook. 2014 Apr 25:1-47. doi: 10.1895/wormbook.1.77.2.


The signaling lipid PI(3,5)P₂ stabilizes V₁-V(o) sector interactions and activates the V-ATPase.

Li SC, Diakov TT, Xu T, Tarsio M, Zhu W, Couoh-Cardel S, Weisman LS, Kane PM.

Mol Biol Cell. 2014 Apr;25(8):1251-62. doi: 10.1091/mbc.E13-10-0563. Epub 2014 Feb 12.


Roles for PI(3,5)P2 in nutrient sensing through TORC1.

Jin N, Mao K, Jin Y, Tevzadze G, Kauffman EJ, Park S, Bridges D, Loewith R, Saltiel AR, Klionsky DJ, Weisman LS.

Mol Biol Cell. 2014 Apr;25(7):1171-85. doi: 10.1091/mbc.E14-01-0021. Epub 2014 Jan 29.


Phosphatidylinositol 3,5-bisphosphate: low abundance, high significance.

McCartney AJ, Zhang Y, Weisman LS.

Bioessays. 2014 Jan;36(1):52-64. doi: 10.1002/bies.201300012. Epub 2013 Oct 28. Review.


Phosphoinositides: tiny lipids with giant impact on cell regulation.

Balla T.

Physiol Rev. 2013 Jul;93(3):1019-137. doi: 10.1152/physrev.00028.2012. Review.


Inhibition of PIKfyve by YM-201636 dysregulates autophagy and leads to apoptosis-independent neuronal cell death.

Martin S, Harper CB, May LM, Coulson EJ, Meunier FA, Osborne SL.

PLoS One. 2013;8(3):e60152. doi: 10.1371/journal.pone.0060152. Epub 2013 Mar 27.


Vac14 protein multimerization is a prerequisite step for Fab1 protein complex assembly and function.

Alghamdi TA, Ho CY, Mrakovic A, Taylor D, Mao D, Botelho RJ.

J Biol Chem. 2013 Mar 29;288(13):9363-72. doi: 10.1074/jbc.M113.453712. Epub 2013 Feb 6.


Critical roles of type III phosphatidylinositol phosphate kinase in murine embryonic visceral endoderm and adult intestine.

Takasuga S, Horie Y, Sasaki J, Sun-Wada GH, Kawamura N, Iizuka R, Mizuno K, Eguchi S, Kofuji S, Kimura H, Yamazaki M, Horie C, Odanaga E, Sato Y, Chida S, Kontani K, Harada A, Katada T, Suzuki A, Wada Y, Ohnishi H, Sasaki T.

Proc Natl Acad Sci U S A. 2013 Jan 29;110(5):1726-31. doi: 10.1073/pnas.1213212110. Epub 2013 Jan 15.


A novel mutation (p.Glu1389AspfsX16) of the phosphoinositide kinase, FYVE finger containing gene found in a Japanese patient with fleck corneal dystrophy.

Kawasaki S, Yamasaki K, Nakagawa H, Shinomiya K, Nakatsukasa M, Nakai Y, Kinoshita S.

Mol Vis. 2012;18:2954-60. Epub 2012 Dec 12.


In vivo, Pikfyve generates PI(3,5)P2, which serves as both a signaling lipid and the major precursor for PI5P.

Zolov SN, Bridges D, Zhang Y, Lee WW, Riehle E, Verma R, Lenk GM, Converso-Baran K, Weide T, Albin RL, Saltiel AR, Meisler MH, Russell MW, Weisman LS.

Proc Natl Acad Sci U S A. 2012 Oct 23;109(43):17472-7. doi: 10.1073/pnas.1203106109. Epub 2012 Oct 9.


Phosphatidylinositol 3,5-bisphosphate plays a role in the activation and subcellular localization of mechanistic target of rapamycin 1.

Bridges D, Ma JT, Park S, Inoki K, Weisman LS, Saltiel AR.

Mol Biol Cell. 2012 Aug;23(15):2955-62. doi: 10.1091/mbc.E11-12-1034. Epub 2012 Jun 13.


Synaptic polarity depends on phosphatidylinositol signaling regulated by myo-inositol monophosphatase in Caenorhabditis elegans.

Kimata T, Tanizawa Y, Can Y, Ikeda S, Kuhara A, Mori I.

Genetics. 2012 Jun;191(2):509-21. doi: 10.1534/genetics.111.137844. Epub 2012 Mar 23.


Endosome maturation.

Huotari J, Helenius A.

EMBO J. 2011 Aug 31;30(17):3481-500. doi: 10.1038/emboj.2011.286. Review.


The Caenorhabditis elegans GARP complex contains the conserved Vps51 subunit and is required to maintain lysosomal morphology.

Luo L, Hannemann M, Koenig S, Hegermann J, Ailion M, Cho MK, Sasidharan N, Zweckstetter M, Rensing SA, Eimer S.

Mol Biol Cell. 2011 Jul 15;22(14):2564-78. doi: 10.1091/mbc.E10-06-0493. Epub 2011 May 25.


The phosphoinositide kinase PIKfyve is vital in early embryonic development: preimplantation lethality of PIKfyve-/- embryos but normality of PIKfyve+/- mice.

Ikonomov OC, Sbrissa D, Delvecchio K, Xie Y, Jin JP, Rappolee D, Shisheva A.

J Biol Chem. 2011 Apr 15;286(15):13404-13. doi: 10.1074/jbc.M111.222364. Epub 2011 Feb 24.


C. elegans TRP channels.

Xiao R, Xu XZ.

Adv Exp Med Biol. 2011;704:323-39. doi: 10.1007/978-94-007-0265-3_18. Review.

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