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Results: 1 to 20 of 89

1.

Altered mucosal immune response after acute lung injury in a murine model of Ataxia Telangiectasia.

Eickmeier O, Kim SY, Herrmann E, Döring C, Duecker R, Voss S, Wehner S, Hölscher C, Pietzner J, Zielen S, Schubert R.

BMC Pulm Med. 2014 May 29;14:93. doi: 10.1186/1471-2466-14-93.

PMID:
24884546
[PubMed - in process]
Free PMC Article
2.

ATM specifically mediates repair of double-strand breaks with blocked DNA ends.

Álvarez-Quilón A, Serrano-Benítez A, Lieberman JA, Quintero C, Sánchez-Gutiérrez D, Escudero LM, Cortés-Ledesma F.

Nat Commun. 2014 Feb 27;5:3347. doi: 10.1038/ncomms4347.

PMID:
24572510
[PubMed - in process]
Free PMC Article
3.

The DNA Damage Response: A Common Pathway in the Regulation of NKG2D and DNAM-1 Ligand Expression in Normal, Infected, and Cancer Cells.

Cerboni C, Fionda C, Soriani A, Zingoni A, Doria M, Cippitelli M, Santoni A.

Front Immunol. 2014 Jan 7;4:508. doi: 10.3389/fimmu.2013.00508. eCollection 2014 Jan 7. Review.

PMID:
24432022
[PubMed]
Free PMC Article
4.

RAG2's acidic hinge restricts repair-pathway choice and promotes genomic stability.

Coussens MA, Wendland RL, Deriano L, Lindsay CR, Arnal SM, Roth DB.

Cell Rep. 2013 Sep 12;4(5):870-8. doi: 10.1016/j.celrep.2013.07.041. Epub 2013 Aug 29.

PMID:
23994475
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

The RAG2 C-terminus and ATM protect genome integrity by controlling antigen receptor gene cleavage.

Chaumeil J, Micsinai M, Ntziachristos P, Roth DB, Aifantis I, Kluger Y, Deriano L, Skok JA.

Nat Commun. 2013;4:2231. doi: 10.1038/ncomms3231.

PMID:
23900513
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

53BP1 is limiting for NHEJ repair in ATM-deficient model systems that are subjected to oncogenic stress or radiation.

Rybanska-Spaeder I, Reynolds TL, Chou J, Prakash M, Jefferson T, Huso DL, Desiderio S, Franco S.

Mol Cancer Res. 2013 Oct;11(10):1223-34. doi: 10.1158/1541-7786.MCR-13-0252-T. Epub 2013 Jul 15.

PMID:
23858098
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Functional intersection of ATM and DNA-dependent protein kinase catalytic subunit in coding end joining during V(D)J recombination.

Lee BS, Gapud EJ, Zhang S, Dorsett Y, Bredemeyer A, George R, Callen E, Daniel JA, Osipovich O, Oltz EM, Bassing CH, Nussenzweig A, Lees-Miller S, Hammel M, Chen BP, Sleckman BP.

Mol Cell Biol. 2013 Sep;33(18):3568-79. doi: 10.1128/MCB.00308-13. Epub 2013 Jul 8.

PMID:
23836881
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

The role of TP53 network in the pathogenesis of chronic lymphocytic leukemia.

Wang C, Wang X.

Int J Clin Exp Pathol. 2013 Jun 15;6(7):1223-9. Print 2013. Review.

PMID:
23826404
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Chromatin remodeling, DNA damage repair and aging.

Liu B, Yip RKh, Zhou Z.

Curr Genomics. 2012 Nov;13(7):533-47. doi: 10.2174/138920212803251373.

PMID:
23633913
[PubMed]
Free PMC Article
10.

ATM influences the efficiency of TCRβ rearrangement, subsequent TCRβ-dependent T cell development, and generation of the pre-selection TCRβ CDR3 repertoire.

Hathcock KS, Bowen S, Livak F, Hodes RJ.

PLoS One. 2013 Apr 23;8(4):e62188. doi: 10.1371/journal.pone.0062188. Print 2013.

PMID:
23626787
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

The ATM signaling network in development and disease.

Stracker TH, Roig I, Knobel PA, Marjanović M.

Front Genet. 2013 Mar 25;4:37. doi: 10.3389/fgene.2013.00037. eCollection 2013.

PMID:
23532176
[PubMed]
Free PMC Article
12.

Concurrent V(D)J recombination and DNA end instability increase interchromosomal trans-rearrangements in ATM-deficient thymocytes.

Bowen S, Wangsa D, Ried T, Livak F, Hodes RJ.

Nucleic Acids Res. 2013 Apr;41(8):4535-48. doi: 10.1093/nar/gkt154. Epub 2013 Mar 6.

PMID:
23470994
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

XRCC4 and XLF form long helical protein filaments suitable for DNA end protection and alignment to facilitate DNA double strand break repair.

Mahaney BL, Hammel M, Meek K, Tainer JA, Lees-Miller SP.

Biochem Cell Biol. 2013 Feb;91(1):31-41. doi: 10.1139/bcb-2012-0058. Epub 2013 Feb 5. Review.

PMID:
23442139
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

The BCL11A transcription factor directly activates RAG gene expression and V(D)J recombination.

Lee BS, Dekker JD, Lee BK, Iyer VR, Sleckman BP, Shaffer AL 3rd, Ippolito GC, Tucker PW.

Mol Cell Biol. 2013 May;33(9):1768-81. doi: 10.1128/MCB.00987-12. Epub 2013 Feb 25.

PMID:
23438597
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Requirement for dicer in survival of proliferating thymocytes experiencing DNA double-strand breaks.

Brady BL, Rupp LJ, Bassing CH.

J Immunol. 2013 Apr 1;190(7):3256-66. doi: 10.4049/jimmunol.1200957. Epub 2013 Feb 20.

PMID:
23427252
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

The ataxia telangiectasia mutated kinase controls Igκ allelic exclusion by inhibiting secondary Vκ-to-Jκ rearrangements.

Steinel NC, Lee BS, Tubbs AT, Bednarski JJ, Schulte E, Yang-Iott KS, Schatz DG, Sleckman BP, Bassing CH.

J Exp Med. 2013 Feb 11;210(2):233-9. doi: 10.1084/jem.20121605. Epub 2013 Feb 4.

PMID:
23382544
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Functional redundancy between the XLF and DNA-PKcs DNA repair factors in V(D)J recombination and nonhomologous DNA end joining.

Oksenych V, Kumar V, Liu X, Guo C, Schwer B, Zha S, Alt FW.

Proc Natl Acad Sci U S A. 2013 Feb 5;110(6):2234-9. doi: 10.1073/pnas.1222573110. Epub 2013 Jan 23.

PMID:
23345432
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

RPA accumulation during class switch recombination represents 5'-3' DNA-end resection during the S-G2/M phase of the cell cycle.

Yamane A, Robbiani DF, Resch W, Bothmer A, Nakahashi H, Oliveira T, Rommel PC, Brown EJ, Nussenzweig A, Nussenzweig MC, Casellas R.

Cell Rep. 2013 Jan 31;3(1):138-47. doi: 10.1016/j.celrep.2012.12.006. Epub 2013 Jan 3.

PMID:
23291097
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Lymphocyte development: integration of DNA damage response signaling.

Bednarski JJ, Sleckman BP.

Adv Immunol. 2012;116:175-204. doi: 10.1016/B978-0-12-394300-2.00006-5. Review.

PMID:
23063077
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Integrated signaling in developing lymphocytes: the role of DNA damage responses.

Bednarski JJ, Sleckman BP.

Cell Cycle. 2012 Nov 15;11(22):4129-34. doi: 10.4161/cc.22021. Epub 2012 Oct 3.

PMID:
23032308
[PubMed - indexed for MEDLINE]
Free PMC Article

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