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Items: 1 to 20 of 147

1.

Synthesis of Isomeric Phosphoubiquitin Chains Reveals that Phosphorylation Controls Deubiquitinase Activity and Specificity.

Huguenin-Dezot N, De Cesare V, Peltier J, Knebel A, Kristaryianto YA, Rogerson DT, Kulathu Y, Trost M, Chin JW.

Cell Rep. 2016 Jul 26;16(4):1180-93. doi: 10.1016/j.celrep.2016.06.064. Epub 2016 Jul 14.

2.

Structures of Rpn1 T1:Rad23 and hRpn13:hPLIC2 Reveal Distinct Binding Mechanisms between Substrate Receptors and Shuttle Factors of the Proteasome.

Chen X, Randles L, Shi K, Tarasov SG, Aihara H, Walters KJ.

Structure. 2016 Aug 2;24(8):1257-70. doi: 10.1016/j.str.2016.05.018. Epub 2016 Jul 7.

PMID:
27396824
3.

Dual RING E3 Architectures Regulate Multiubiquitination and Ubiquitin Chain Elongation by APC/C.

Brown NG, VanderLinden R, Watson ER, Weissmann F, Ordureau A, Wu KP, Zhang W, Yu S, Mercredi PY, Harrison JS, Davidson IF, Qiao R, Lu Y, Dube P, Brunner MR, Grace CR, Miller DJ, Haselbach D, Jarvis MA, Yamaguchi M, Yanishevski D, Petzold G, Sidhu SS, Kuhlman B, Kirschner MW, Harper JW, Peters JM, Stark H, Schulman BA.

Cell. 2016 Jun 2;165(6):1440-53. doi: 10.1016/j.cell.2016.05.037.

4.

Conserved Sequence Preferences Contribute to Substrate Recognition by the Proteasome.

Yu H, Singh Gautam AK, Wilmington SR, Wylie D, Martinez-Fonts K, Kago G, Warburton M, Chavali S, Inobe T, Finkelstein IJ, Babu MM, Matouschek A.

J Biol Chem. 2016 Jul 8;291(28):14526-39. doi: 10.1074/jbc.M116.727578. Epub 2016 May 17.

5.

Recognition of Lys48-Linked Di-ubiquitin and Deubiquitinating Activities of the SARS Coronavirus Papain-like Protease.

Békés M, van der Heden van Noort GJ, Ekkebus R, Ovaa H, Huang TT, Lima CD.

Mol Cell. 2016 May 19;62(4):572-85. doi: 10.1016/j.molcel.2016.04.016.

PMID:
27203180
6.

USP14 deubiquitinates proteasome-bound substrates that are ubiquitinated at multiple sites.

Lee BH, Lu Y, Prado MA, Shi Y, Tian G, Sun S, Elsasser S, Gygi SP, King RW, Finley D.

Nature. 2016 Apr 21;532(7599):398-401. doi: 10.1038/nature17433. Epub 2016 Apr 13.

PMID:
27074503
7.

Ubiquitin modifications.

Swatek KN, Komander D.

Cell Res. 2016 Apr;26(4):399-422. doi: 10.1038/cr.2016.39. Epub 2016 Mar 25. Review.

8.

A decade of the anaphase-promoting complex in the nervous system.

Huang J, Bonni A.

Genes Dev. 2016 Mar 15;30(6):622-38. doi: 10.1101/gad.274324.115. Review.

PMID:
26980187
9.

A Rapid and Versatile Method for Generating Proteins with Defined Ubiquitin Chains.

Martinez-Fonts K, Matouschek A.

Biochemistry. 2016 Mar 29;55(12):1898-908. doi: 10.1021/acs.biochem.5b01310. Epub 2016 Mar 17.

PMID:
26943792
10.

Rpn1 provides adjacent receptor sites for substrate binding and deubiquitination by the proteasome.

Shi Y, Chen X, Elsasser S, Stocks BB, Tian G, Lee BH, Shi Y, Zhang N, de Poot SA, Tuebing F, Sun S, Vannoy J, Tarasov SG, Engen JR, Finley D, Walters KJ.

Science. 2016 Feb 19;351(6275). pii: aad9421. doi: 10.1126/science.aad9421.

11.

Deubiquitylation of Protein Cargo Is Not an Essential Step in Exosome Formation.

Huebner AR, Cheng L, Somparn P, Knepper MA, Fenton RA, Pisitkun T.

Mol Cell Proteomics. 2016 May;15(5):1556-71. doi: 10.1074/mcp.M115.054965. Epub 2016 Feb 16.

PMID:
26884507
12.

Control of APC/C-dependent ubiquitin chain elongation by reversible phosphorylation.

Craney A, Kelly A, Jia L, Fedrigo I, Yu H, Rape M.

Proc Natl Acad Sci U S A. 2016 Feb 9;113(6):1540-5. doi: 10.1073/pnas.1522423113. Epub 2016 Jan 25.

13.

Gates, Channels, and Switches: Elements of the Proteasome Machine.

Finley D, Chen X, Walters KJ.

Trends Biochem Sci. 2016 Jan;41(1):77-93. doi: 10.1016/j.tibs.2015.10.009. Epub 2015 Nov 28. Review.

PMID:
26643069
14.

Multiplexed, Proteome-Wide Protein Expression Profiling: Yeast Deubiquitylating Enzyme Knockout Strains.

Isasa M, Rose CM, Elsasser S, Navarrete-Perea J, Paulo JA, Finley DJ, Gygi SP.

J Proteome Res. 2015 Dec 4;14(12):5306-17. doi: 10.1021/acs.jproteome.5b00802. Epub 2015 Nov 4.

15.

Skp1 in lung cancer: clinical significance and therapeutic efficacy of its small molecule inhibitors.

Liu YQ, Wang XL, Cheng X, Lu YZ, Wang GZ, Li XC, Zhang J, Wen ZS, Huang ZL, Gao QL, Yang LN, Cheng YX, Tao SC, Liu J, Zhou GB.

Oncotarget. 2015 Oct 27;6(33):34953-67. doi: 10.18632/oncotarget.5547.

16.

Multiplexed Targeted Mass Spectrometry-Based Assays for the Quantification of N-Linked Glycosite-Containing Peptides in Serum.

Thomas SN, Harlan R, Chen J, Aiyetan P, Liu Y, Sokoll LJ, Aebersold R, Chan DW, Zhang H.

Anal Chem. 2015 Nov 3;87(21):10830-8. doi: 10.1021/acs.analchem.5b02063. Epub 2015 Oct 21.

17.

RING Dimerization Links Higher-Order Assembly of TRIM5α to Synthesis of K63-Linked Polyubiquitin.

Yudina Z, Roa A, Johnson R, Biris N, de Souza Aranha Vieira DA, Tsiperson V, Reszka N, Taylor AB, Hart PJ, Demeler B, Diaz-Griffero F, Ivanov DN.

Cell Rep. 2015 Aug 4;12(5):788-97. doi: 10.1016/j.celrep.2015.06.072. Epub 2015 Jul 23.

18.

The Proteasome Distinguishes between Heterotypic and Homotypic Lysine-11-Linked Polyubiquitin Chains.

Grice GL, Lobb IT, Weekes MP, Gygi SP, Antrobus R, Nathan JA.

Cell Rep. 2015 Jul 28;12(4):545-53. doi: 10.1016/j.celrep.2015.06.061. Epub 2015 Jul 16.

19.

Quantifying ubiquitin signaling.

Ordureau A, Münch C, Harper JW.

Mol Cell. 2015 May 21;58(4):660-76. doi: 10.1016/j.molcel.2015.02.020. Review.

20.

Substrate degradation by the proteasome: a single-molecule kinetic analysis.

Lu Y, Lee BH, King RW, Finley D, Kirschner MW.

Science. 2015 Apr 10;348(6231):1250834. doi: 10.1126/science.1250834.

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