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Items: 1 to 20 of 85

1.

Time-resolved multimodal analysis of Src Homology 2 (SH2) domain binding in signaling by receptor tyrosine kinases.

Jadwin JA, Oh D, Curran TG, Ogiue-Ikeda M, Jia L, White FM, Machida K, Yu J, Mayer BJ.

Elife. 2016 Apr 12;5. pii: e11835. doi: 10.7554/eLife.11835.

2.

Targeting Syk in Autoimmune Rheumatic Diseases.

Deng GM, Kyttaris VC, Tsokos GC.

Front Immunol. 2016 Mar 7;7:78. doi: 10.3389/fimmu.2016.00078. eCollection 2016. Review.

3.

Novel autophosphorylation sites of Src family kinases regulate kinase activity and SH2 domain-binding capacity.

Weir ME, Mann JE, Corwin T, Fulton ZW, Hao JM, Maniscalco JF, Kenney MC, Roman Roque KM, Chapdelaine EF, Stelzl U, Deming PB, Ballif BA, Hinkle KL.

FEBS Lett. 2016 Apr;590(8):1042-52. doi: 10.1002/1873-3468.12144. Epub 2016 Apr 13.

PMID:
27001024
4.

Unmasking determinants of specificity in the human kinome.

Creixell P, Palmeri A, Miller CJ, Lou HJ, Santini CC, Nielsen M, Turk BE, Linding R.

Cell. 2015 Sep 24;163(1):187-201. doi: 10.1016/j.cell.2015.08.057. Epub 2015 Sep 17.

5.

Kinome-wide decoding of network-attacking mutations rewiring cancer signaling.

Creixell P, Schoof EM, Simpson CD, Longden J, Miller CJ, Lou HJ, Perryman L, Cox TR, Zivanovic N, Palmeri A, Wesolowska-Andersen A, Helmer-Citterich M, Ferkinghoff-Borg J, Itamochi H, Bodenmiller B, Erler JT, Turk BE, Linding R.

Cell. 2015 Sep 24;163(1):202-17. doi: 10.1016/j.cell.2015.08.056. Epub 2015 Sep 17.

6.

Structural insights into the intertwined dimer of fyn SH2.

Huculeci R, Garcia-Pino A, Buts L, Lenaerts T, van Nuland N.

Protein Sci. 2015 Dec;24(12):1964-78. doi: 10.1002/pro.2806. Epub 2015 Oct 7.

PMID:
26384592
7.

SH2-PLA: a sensitive in-solution approach for quantification of modular domain binding by proximity ligation and real-time PCR.

Thompson CM, Bloom LR, Ogiue-Ikeda M, Machida K.

BMC Biotechnol. 2015 Jun 26;15:60. doi: 10.1186/s12896-015-0169-1.

8.

Regions outside of conserved PxxPxR motifs drive the high affinity interaction of GRB2 with SH3 domain ligands.

Bartelt RR, Light J, Vacaflores A, Butcher A, Pandian M, Nash P, Houtman JC.

Biochim Biophys Acta. 2015 Oct;1853(10 Pt A):2560-9. doi: 10.1016/j.bbamcr.2015.06.002. Epub 2015 Jun 12.

PMID:
26079855
9.

Phospho-tyrosine dependent protein-protein interaction network.

Grossmann A, Benlasfer N, Birth P, Hegele A, Wachsmuth F, Apelt L, Stelzl U.

Mol Syst Biol. 2015 Mar 26;11(3):794. doi: 10.15252/msb.20145968.

10.

Toward a systems-level view of dynamic phosphorylation networks.

Newman RH, Zhang J, Zhu H.

Front Genet. 2014 Aug 15;5:263. doi: 10.3389/fgene.2014.00263. eCollection 2014. Review.

11.

The development and application of a quantitative peptide microarray based approach to protein interaction domain specificity space.

Engelmann BW, Kim Y, Wang M, Peters B, Rock RS, Nash PD.

Mol Cell Proteomics. 2014 Dec;13(12):3647-62. doi: 10.1074/mcp.O114.038695. Epub 2014 Aug 18.

12.

Dimeric switch of Hakai-truncated monomers during substrate recognition: insights from solution studies and NMR structure.

Mukherjee M, Jing-Song F, Ramachandran S, Guy GR, Sivaraman J.

J Biol Chem. 2014 Sep 12;289(37):25611-23. doi: 10.1074/jbc.M114.592840. Epub 2014 Jul 29.

13.

Probing SH2-domains using Inhibitor Affinity Purification (IAP).

Höfener M, Heinzlmeir S, Kuster B, Sewald N.

Proteome Sci. 2014 Jul 16;12:41. doi: 10.1186/1477-5956-12-41. eCollection 2014.

14.

The molecular regulation of Janus kinase (JAK) activation.

Babon JJ, Lucet IS, Murphy JM, Nicola NA, Varghese LN.

Biochem J. 2014 Aug 15;462(1):1-13. doi: 10.1042/BJ20140712. Review.

15.

Getting Syk: spleen tyrosine kinase as a therapeutic target.

Geahlen RL.

Trends Pharmacol Sci. 2014 Aug;35(8):414-22. doi: 10.1016/j.tips.2014.05.007. Epub 2014 Jun 26. Review.

16.

Opsismodysplasia resulting from an insertion mutation in the SH2 domain, which destabilizes INPPL1.

Li B, Krakow D, Nickerson DA, Bamshad MJ; University of Washington Center for Mendelian Genomics, Chang Y, Lachman RS, Yilmaz A, Kayserili H, Cohn DH.

Am J Med Genet A. 2014 Sep;164A(9):2407-11. doi: 10.1002/ajmg.a.36640. Epub 2014 Jun 20. No abstract available.

17.

Directed network wiring identifies a key protein interaction in embryonic stem cell differentiation.

Yasui N, Findlay GM, Gish GD, Hsiung MS, Huang J, Tucholska M, Taylor L, Smith L, Boldridge WC, Koide A, Pawson T, Koide S.

Mol Cell. 2014 Jun 19;54(6):1034-41. doi: 10.1016/j.molcel.2014.05.002. Epub 2014 Jun 5.

18.

Enhanced prediction of Src homology 2 (SH2) domain binding potentials using a fluorescence polarization-derived c-Met, c-Kit, ErbB, and androgen receptor interactome.

Leung KK, Hause RJ Jr, Barkinge JL, Ciaccio MF, Chuu CP, Jones RB.

Mol Cell Proteomics. 2014 Jul;13(7):1705-23. doi: 10.1074/mcp.M113.034876. Epub 2014 Apr 12.

19.

Structural basis of recognition of interferon-α receptor by tyrosine kinase 2.

Wallweber HJ, Tam C, Franke Y, Starovasnik MA, Lupardus PJ.

Nat Struct Mol Biol. 2014 May;21(5):443-8. doi: 10.1038/nsmb.2807. Epub 2014 Apr 6.

20.

Solubility of recombinant Src homology 2 domains expressed in E. coli can be predicted by TANGO.

Andersen TC, Lindsjø K, Hem CD, Koll L, Kristiansen PE, Skjeldal L, Andreotti AH, Spurkland A.

BMC Biotechnol. 2014 Jan 14;14:3. doi: 10.1186/1472-6750-14-3.

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