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Items: 11

1.

Validated LC--MS/MS method for determination of YH-8, a novel PKnB inhibitor, in rat plasma and its application to pharmacokinetic study.

Zhai Q, Pang J, Li G, Li C, Yang X, Yu L, Wang Y, Li J, You X.

Acta Pharm Sin B. 2015 Sep;5(5):467-72. doi: 10.1016/j.apsb.2015.04.001. Epub 2015 May 28.

2.

Mycobacterium tuberculosis Serine/Threonine Protein Kinases.

Prisic S, Husson RN.

Microbiol Spectr. 2014 Oct;2(5). doi: 10.1128/microbiolspec.MGM2-0006-2013. Review.

3.

Enhanced ranking of PknB Inhibitors using data fusion methods.

Seal A, Yogeeswari P, Sriram D; OSDD Consortium, Wild DJ.

J Cheminform. 2013 Jan 14;5(1):2. doi: 10.1186/1758-2946-5-2.

4.

Bacterial cell division regulation by Ser/Thr kinases: a structural perspective.

Ruggiero A, De Simone P, Smaldone G, Squeglia F, Berisio R.

Curr Protein Pept Sci. 2012 Dec;13(8):756-66. Review.

5.

Structural analysis of Staphylococcus aureus serine/threonine kinase PknB.

Rakette S, Donat S, Ohlsen K, Stehle T.

PLoS One. 2012;7(6):e39136. doi: 10.1371/journal.pone.0039136. Epub 2012 Jun 11.

6.

New Test System for Serine/Threonine Protein Kinase Inhibitors Screening: E. coli APHVIII/Pk25 design.

Bekker OB, Alekseeva MG, Osolodkin DI, Palyulin VA, Elizarov SM, Zefirov NS, Danilenko VN.

Acta Naturae. 2010 Jul;2(3):110-21.

7.

Substituted aminopyrimidine protein kinase B (PknB) inhibitors show activity against Mycobacterium tuberculosis.

Chapman TM, Bouloc N, Buxton RS, Chugh J, Lougheed KE, Osborne SA, Saxty B, Smerdon SJ, Taylor DL, Whalley D.

Bioorg Med Chem Lett. 2012 May 1;22(9):3349-53. doi: 10.1016/j.bmcl.2012.02.107. Epub 2012 Mar 14.

8.

Proteins with complex architecture as potential targets for drug design: a case study of Mycobacterium tuberculosis.

Mészáros B, Tóth J, Vértessy BG, Dosztányi Z, Simon I.

PLoS Comput Biol. 2011 Jul;7(7):e1002118. doi: 10.1371/journal.pcbi.1002118. Epub 2011 Jul 21.

9.

Asymmetric enzymatic glycosylation of mitoxantrone.

Zhou M, Thorson JS.

Org Lett. 2011 May 20;13(10):2786-8. doi: 10.1021/ol200977u. Epub 2011 Apr 29.

10.

Evolution of protein binding modes in homooligomers.

Dayhoff JE, Shoemaker BA, Bryant SH, Panchenko AR.

J Mol Biol. 2010 Jan 29;395(4):860-70. doi: 10.1016/j.jmb.2009.10.052. Epub 2009 Oct 30.

11.

Auto-activation mechanism of the Mycobacterium tuberculosis PknB receptor Ser/Thr kinase.

Mieczkowski C, Iavarone AT, Alber T.

EMBO J. 2008 Dec 3;27(23):3186-97. doi: 10.1038/emboj.2008.236. Epub 2008 Nov 13.

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