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Results: 9

Cited In for PubMed (Select 16651634)


Genomic amplification and high expression of EGFR are key targetable oncogenic events in malignant peripheral nerve sheath tumor.

Du X, Yang J, Ylipää A, Zhu Z.

J Hematol Oncol. 2013 Dec 17;6:93. doi: 10.1186/1756-8722-6-93.


Malignant peripheral nerve sheath tumor invasion requires aberrantly expressed EGF receptors and is variably enhanced by multiple EGF family ligands.

Byer SJ, Brossier NM, Peavler LT, Eckert JM, Watkins S, Roth KA, Carroll SL.

J Neuropathol Exp Neurol. 2013 Mar;72(3):219-33. doi: 10.1097/NEN.0b013e3182859939.


Preclincial testing of sorafenib and RAD001 in the Nf(flox/flox) ;DhhCre mouse model of plexiform neurofibroma using magnetic resonance imaging.

Wu J, Dombi E, Jousma E, Scott Dunn R, Lindquist D, Schnell BM, Kim MO, Kim A, Widemann BC, Cripe TP, Ratner N.

Pediatr Blood Cancer. 2012 Feb;58(2):173-80. doi: 10.1002/pbc.23015. Epub 2011 Feb 11.


Nf1 mutation expands an EGFR-dependent peripheral nerve progenitor that confers neurofibroma tumorigenic potential.

Williams JP, Wu J, Johansson G, Rizvi TA, Miller SC, Geiger H, Malik P, Li W, Mukouyama YS, Cancelas JA, Ratner N.

Cell Stem Cell. 2008 Dec 4;3(6):658-69. doi: 10.1016/j.stem.2008.10.003.


Suppression of proliferation of two independent NF1 malignant peripheral nerve sheath tumor cell lines by the pan-ErbB inhibitor CI-1033.

Dilworth JT, Wojtkowiak JW, Mathieu P, Tainsky MA, Reiners JJ Jr, Mattingly RR, Hancock CN.

Cancer Biol Ther. 2008 Dec;7(12):1938-46. Epub 2008 Dec 7.


How does the Schwann cell lineage form tumors in NF1?

Carroll SL, Ratner N.

Glia. 2008 Nov 1;56(14):1590-605. doi: 10.1002/glia.20776. Review.


Frequent EGFR Positivity and Overexpression in High-Grade Areas of Human MPNSTs.

Tabone-Eglinger S, Bahleda R, Côté JF, Terrier P, Vidaud D, Cayre A, Beauchet A, Théou-Anton N, Terrier-Lacombe MJ, Lemoine A, Penault-Llorca F, Le Cesne A, Emile JF.

Sarcoma. 2008;2008:849156. doi: 10.1155/2008/849156.


Mast cells can contribute to axon-glial dissociation and fibrosis in peripheral nerve.

Monk KR, Wu J, Williams JP, Finney BA, Fitzgerald ME, Filippi MD, Ratner N.

Neuron Glia Biol. 2007 Aug;3(3):233-44. doi: 10.1017/S1740925X08000021.


Plexiform and dermal neurofibromas and pigmentation are caused by Nf1 loss in desert hedgehog-expressing cells.

Wu J, Williams JP, Rizvi TA, Kordich JJ, Witte D, Meijer D, Stemmer-Rachamimov AO, Cancelas JA, Ratner N.

Cancer Cell. 2008 Feb;13(2):105-16. doi: 10.1016/j.ccr.2007.12.027.

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