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The Mammalian Blood-Testis Barrier: Its Biology and Regulation.

Mruk DD, Cheng CY.

Endocr Rev. 2015 Oct;36(5):564-91. doi: 10.1210/er.2014-1101. Epub 2015 Sep 10. Review. Erratum in: Endocr Rev. 2015 Dec;36(6):681.


The Human Papillomavirus E6 PDZ Binding Motif: From Life Cycle to Malignancy.

Ganti K, Broniarczyk J, Manoubi W, Massimi P, Mittal S, Pim D, Szalmas A, Thatte J, Thomas M, Tomaić V, Banks L.

Viruses. 2015 Jul 2;7(7):3530-51. doi: 10.3390/v7072785. Review.


The APC tumor suppressor is required for epithelial cell polarization and three-dimensional morphogenesis.

Lesko AC, Goss KH, Yang FF, Schwertner A, Hulur I, Onel K, Prosperi JR.

Biochim Biophys Acta. 2015 Mar;1853(3):711-23. doi: 10.1016/j.bbamcr.2014.12.036. Epub 2015 Jan 8.


Scribble modulates the MAPK/Fra1 pathway to disrupt luminal and ductal integrity and suppress tumour formation in the mammary gland.

Godde NJ, Sheridan JM, Smith LK, Pearson HB, Britt KL, Galea RC, Yates LL, Visvader JE, Humbert PO.

PLoS Genet. 2014 May 22;10(5):e1004323. doi: 10.1371/journal.pgen.1004323. eCollection 2014 May.


Identifying novel protein complexes in cancer cells using epitope-tagging of endogenous human genes and affinity-purification mass spectrometry.

Song J, Hao Y, Du Z, Wang Z, Ewing RM.

J Proteome Res. 2012 Dec 7;11(12):5630-41. doi: 10.1021/pr300598t. Epub 2012 Nov 7.


Reconstruction of human papillomavirus type 16-mediated early-stage neoplasia implicates E6/E7 deregulation and the loss of contact inhibition in neoplastic progression.

Isaacson Wechsler E, Wang Q, Roberts I, Pagliarulo E, Jackson D, Untersperger C, Coleman N, Griffin H, Doorbar J.

J Virol. 2012 Jun;86(11):6358-64. doi: 10.1128/JVI.07069-11. Epub 2012 Mar 28.


The E6 oncoprotein from HPV16 enhances the canonical Wnt/β-catenin pathway in skin epidermis in vivo.

Bonilla-Delgado J, Bulut G, Liu X, Cortés-Malagón EM, Schlegel R, Flores-Maldonado C, Contreras RG, Chung SH, Lambert PF, Uren A, Gariglio P.

Mol Cancer Res. 2012 Feb;10(2):250-8. doi: 10.1158/1541-7786.MCR-11-0287. Epub 2011 Dec 7.


DomPep--a general method for predicting modular domain-mediated protein-protein interactions.

Li L, Zhao B, Du J, Zhang K, Ling CX, Li SS.

PLoS One. 2011;6(10):e25528. doi: 10.1371/journal.pone.0025528. Epub 2011 Oct 7.


SCRIB expression is deregulated in human prostate cancer, and its deficiency in mice promotes prostate neoplasia.

Pearson HB, Perez-Mancera PA, Dow LE, Ryan A, Tennstedt P, Bogani D, Elsum I, Greenfield A, Tuveson DA, Simon R, Humbert PO.

J Clin Invest. 2011 Nov;121(11):4257-67. doi: 10.1172/JCI58509. Epub 2011 Oct 3.


WIF1 is a frequent target for epigenetic silencing in squamous cell carcinoma of the cervix.

Delmas AL, Riggs BM, Pardo CE, Dyer LM, Darst RP, Izumchenko EG, Monroe M, Hakam A, Kladde MP, Siegel EM, Brown KD.

Carcinogenesis. 2011 Nov;32(11):1625-33. doi: 10.1093/carcin/bgr193. Epub 2011 Aug 26.


The avian influenza virus NS1 ESEV PDZ binding motif associates with Dlg1 and Scribble to disrupt cellular tight junctions.

Golebiewski L, Liu H, Javier RT, Rice AP.

J Virol. 2011 Oct;85(20):10639-48. doi: 10.1128/JVI.05070-11. Epub 2011 Aug 17.


The mechanism and implications of hScrib regulation of ERK.

Nagasaka K, Massimi P, Pim D, Subbaiah VK, Kranjec C, Nakagawa S, Yano T, Taketani Y, Banks L.

Small GTPases. 2010 Sep;1(2):108-112.


Epithelial cell polarity: a major gatekeeper against cancer?

Royer C, Lu X.

Cell Death Differ. 2011 Sep;18(9):1470-7. doi: 10.1038/cdd.2011.60. Epub 2011 May 27. Review.


Protein complexes that control renal epithelial polarity.

Pieczynski J, Margolis B.

Am J Physiol Renal Physiol. 2011 Mar;300(3):F589-601. doi: 10.1152/ajprenal.00615.2010. Epub 2011 Jan 12. Review.


NFX1 plays a role in human papillomavirus type 16 E6 activation of NFkappaB activity.

Xu M, Katzenellenbogen RA, Grandori C, Galloway DA.

J Virol. 2010 Nov;84(21):11461-9. doi: 10.1128/JVI.00538-10. Epub 2010 Aug 25.


The ESEV PDZ-binding motif of the avian influenza A virus NS1 protein protects infected cells from apoptosis by directly targeting Scribble.

Liu H, Golebiewski L, Dow EC, Krug RM, Javier RT, Rice AP.

J Virol. 2010 Nov;84(21):11164-74. doi: 10.1128/JVI.01278-10. Epub 2010 Aug 11.


Scribble interacts with beta-catenin to localize synaptic vesicles to synapses.

Sun Y, Aiga M, Yoshida E, Humbert PO, Bamji SX.

Mol Biol Cell. 2009 Jul;20(14):3390-400. doi: 10.1091/mbc.E08-12-1172. Epub 2009 May 20.


Erbin controls dendritic morphogenesis by regulating localization of delta-catenin.

Arikkath J, Israely I, Tao Y, Mei L, Liu X, Reichardt LF.

J Neurosci. 2008 Jul 9;28(28):7047-56. doi: 10.1523/JNEUROSCI.0451-08.2008.


Cellular binding partners of the human papillomavirus E6 protein.

Tungteakkhun SS, Duerksen-Hughes PJ.

Arch Virol. 2008;153(3):397-408. doi: 10.1007/s00705-007-0022-5. Epub 2008 Jan 3. Review.


LKB1 and AMPK maintain epithelial cell polarity under energetic stress.

Mirouse V, Swick LL, Kazgan N, St Johnston D, Brenman JE.

J Cell Biol. 2007 May 7;177(3):387-92. Epub 2007 Apr 30. Retraction in: J Cell Biol. 2013 Oct 28;203(2):373.

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