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Items: 1 to 20 of 45


The Chemical Biology of Molecular Chaperones--Implications for Modulation of Proteostasis.

Brandvold KR, Morimoto RI.

J Mol Biol. 2015 Sep 11;427(18):2931-47. doi: 10.1016/j.jmb.2015.05.010. Epub 2015 May 21. Review.


HSP90 inhibition enhances antimitotic drug-induced mitotic arrest and cell death in preclinical models of non-small cell lung cancer.

O'Connell BC, O'Callaghan K, Tillotson B, Douglas M, Hafeez N, West KA, Stern H, Ali JA, Changelian P, Fritz CC, Palombella VJ, McGovern K, Kutok JL.

PLoS One. 2014 Dec 26;9(12):e115228. doi: 10.1371/journal.pone.0115228. eCollection 2014.


BCAS2 promotes prostate cancer cells proliferation by enhancing AR mRNA transcription and protein stability.

Kuo PC, Huang CW, Lee CI, Chang HW, Hsieh SW, Chung YP, Lee MS, Huang CS, Tsao LP, Tsao YP, Chen SL.

Br J Cancer. 2015 Jan 20;112(2):391-402. doi: 10.1038/bjc.2014.603. Epub 2014 Dec 2.


Glucocorticosteroids trigger reactivation of human cytomegalovirus from latently infected myeloid cells and increase the risk for HCMV infection in D+R+ liver transplant patients.

Van Damme E, Sauviller S, Lau B, Kesteleyn B, Griffiths P, Burroughs A, Emery V, Sinclair J, Van Loock M.

J Gen Virol. 2015 Jan;96(Pt 1):131-43. doi: 10.1099/vir.0.069872-0. Epub 2014 Oct 13.


Experience and the ever-changing brain: what the transcriptome can reveal.

Rubin TG, Gray JD, McEwen BS.

Bioessays. 2014 Nov;36(11):1072-81. doi: 10.1002/bies.201400095. Epub 2014 Sep 11. Review.


Glucocorticoid receptor function regulated by coordinated action of the Hsp90 and Hsp70 chaperone cycles.

Kirschke E, Goswami D, Southworth D, Griffin PR, Agard DA.

Cell. 2014 Jun 19;157(7):1685-97. doi: 10.1016/j.cell.2014.04.038.


RNA-Seq transcriptome profiling identifies CRISPLD2 as a glucocorticoid responsive gene that modulates cytokine function in airway smooth muscle cells.

Himes BE, Jiang X, Wagner P, Hu R, Wang Q, Klanderman B, Whitaker RM, Duan Q, Lasky-Su J, Nikolos C, Jester W, Johnson M, Panettieri RA Jr, Tantisira KG, Weiss ST, Lu Q.

PLoS One. 2014 Jun 13;9(6):e99625. doi: 10.1371/journal.pone.0099625. eCollection 2014.


Facile synthesis of a fluorescent cyclosporin a analogue to study cyclophilin 40 and cyclophilin 18 ligands.

Gaali S, Kozany C, Hoogeland B, Klein M, Hausch F.

ACS Med Chem Lett. 2010 Aug 25;1(9):536-9. doi: 10.1021/ml1001272. eCollection 2010 Dec 9.


From pharmacogenetics to pharmacogenomics: the way toward the personalization of antidepressant treatment.

Fabbri C, Porcelli S, Serretti A.

Can J Psychiatry. 2014 Feb;59(2):62-75. Review.


Coordinated regulation of nuclear receptor CAR by CCRP/DNAJC7, HSP70 and the ubiquitin-proteasome system.

Timsit YE, Negishi M.

PLoS One. 2014 May 2;9(5):e96092. doi: 10.1371/journal.pone.0096092. eCollection 2014.


Depletion of FKBP51 in female mice shapes HPA axis activity.

Hoeijmakers L, Harbich D, Schmid B, Lucassen PJ, Wagner KV, Schmidt MV, Hartmann J.

PLoS One. 2014 Apr 23;9(4):e95796. doi: 10.1371/journal.pone.0095796. eCollection 2014.


Prenatal alcohol exposure modifies glucocorticoid receptor subcellular distribution in the medial prefrontal cortex and impairs frontal cortex-dependent learning.

Allan AM, Goggin SL, Caldwell KK.

PLoS One. 2014 Apr 22;9(4):e96200. doi: 10.1371/journal.pone.0096200. eCollection 2014.


MicroRNAs as tools to predict glucocorticoid response in inflammatory bowel diseases.

De Iudicibus S, Lucafò M, Martelossi S, Pierobon C, Ventura A, Decorti G.

World J Gastroenterol. 2013 Nov 28;19(44):7947-54. doi: 10.3748/wjg.v19.i44.7947. Review.


Specificity in the actions of the UBR1 ubiquitin ligase in the degradation of nuclear receptors.

Sultana R, Theodoraki MA, Caplan AJ.

FEBS Open Bio. 2013 Sep 17;3:394-7. doi: 10.1016/j.fob.2013.09.003. eCollection 2013.


Small-molecule hormones: molecular mechanisms of action.

Puzianowska-Kuznicka M, Pawlik-Pachucka E, Owczarz M, Budzińska M, Polosak J.

Int J Endocrinol. 2013;2013:601246. doi: 10.1155/2013/601246. Epub 2013 Feb 28.


Differences in FKBP51 regulation following chronic social defeat stress correlate with individual stress sensitivity: influence of paroxetine treatment.

Wagner KV, Marinescu D, Hartmann J, Wang XD, Labermaier C, Scharf SH, Liebl C, Uhr M, Holsboer F, Müller MB, Schmidt MV.

Neuropsychopharmacology. 2012 Dec;37(13):2797-808. doi: 10.1038/npp.2012.150. Epub 2012 Aug 8.


Analysis of the tau-associated proteome reveals that exchange of Hsp70 for Hsp90 is involved in tau degradation.

Thompson AD, Scaglione KM, Prensner J, Gillies AT, Chinnaiyan A, Paulson HL, Jinwal UK, Dickey CA, Gestwicki JE.

ACS Chem Biol. 2012 Oct 19;7(10):1677-86. doi: 10.1021/cb3002599. Epub 2012 Jul 25.


Genome-wide landscape of liver X receptor chromatin binding and gene regulation in human macrophages.

Pehkonen P, Welter-Stahl L, Diwo J, Ryynänen J, Wienecke-Baldacchino A, Heikkinen S, Treuter E, Steffensen KR, Carlberg C.

BMC Genomics. 2012 Jan 31;13:50. doi: 10.1186/1471-2164-13-50.


Interaction between FKBP5 and childhood trauma and risk of aggressive behavior.

Bevilacqua L, Carli V, Sarchiapone M, George DK, Goldman D, Roy A, Enoch MA.

Arch Gen Psychiatry. 2012 Jan;69(1):62-70. doi: 10.1001/archgenpsychiatry.2011.152.

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