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Results: 1 to 20 of 47

1.

Specific deletion of Cdc42 does not affect meiotic spindle organization/migration and homologous chromosome segregation but disrupts polarity establishment and cytokinesis in mouse oocytes.

Wang ZB, Jiang ZZ, Zhang QH, Hu MW, Huang L, Ou XH, Guo L, Ouyang YC, Hou Y, Brakebusch C, Schatten H, Sun QY.

Mol Biol Cell. 2013 Dec;24(24):3832-41. doi: 10.1091/mbc.E13-03-0123. Epub 2013 Oct 16.

PMID:
24131996
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Cdc42 deficiency causes ciliary abnormalities and cystic kidneys.

Choi SY, Chacon-Heszele MF, Huang L, McKenna S, Wilson FP, Zuo X, Lipschutz JH.

J Am Soc Nephrol. 2013 Sep;24(9):1435-50. doi: 10.1681/ASN.2012121236. Epub 2013 Jun 13.

PMID:
23766535
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Divergent functions of the Rho GTPases Rac1 and Cdc42 in podocyte injury.

Blattner SM, Hodgin JB, Nishio M, Wylie SA, Saha J, Soofi AA, Vining C, Randolph A, Herbach N, Wanke R, Atkins KB, Gyung Kang H, Henger A, Brakebusch C, Holzman LB, Kretzler M.

Kidney Int. 2013 Nov;84(5):920-30. doi: 10.1038/ki.2013.175. Epub 2013 May 15.

PMID:
23677246
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Yap- and Cdc42-dependent nephrogenesis and morphogenesis during mouse kidney development.

Reginensi A, Scott RP, Gregorieff A, Bagherie-Lachidan M, Chung C, Lim DS, Pawson T, Wrana J, McNeill H.

PLoS Genet. 2013 Mar;9(3):e1003380. doi: 10.1371/journal.pgen.1003380. Epub 2013 Mar 21.

PMID:
23555292
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

CDC42 is required for tissue lamination and cell survival in the mouse retina.

Heynen SR, Meneau I, Caprara C, Samardzija M, Imsand C, Levine EM, Grimm C.

PLoS One. 2013;8(1):e53806. doi: 10.1371/journal.pone.0053806. Epub 2013 Jan 23.

PMID:
23372671
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Cdc42-dependent structural development of auditory supporting cells is required for wound healing at adulthood.

Anttonen T, Kirjavainen A, Belevich I, Laos M, Richardson WD, Jokitalo E, Brakebusch C, Pirvola U.

Sci Rep. 2012;2:978. doi: 10.1038/srep00978. Epub 2012 Dec 17.

PMID:
23248743
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

CDC42 is required for structural patterning of the lung during development.

Wan H, Liu C, Wert SE, Xu W, Liao Y, Zheng Y, Whitsett JA.

Dev Biol. 2013 Feb 1;374(1):46-57. doi: 10.1016/j.ydbio.2012.11.030. Epub 2012 Dec 5.

PMID:
23219958
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Myelin is dependent on the Charcot-Marie-Tooth Type 4H disease culprit protein FRABIN/FGD4 in Schwann cells.

Horn M, Baumann R, Pereira JA, Sidiropoulos PN, Somandin C, Welzl H, Stendel C, Lühmann T, Wessig C, Toyka KV, Relvas JB, Senderek J, Suter U.

Brain. 2012 Dec;135(Pt 12):3567-83. doi: 10.1093/brain/aws275. Epub 2012 Nov 20.

PMID:
23171661
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Polarity and stratification of the epidermis.

Muroyama A, Lechler T.

Semin Cell Dev Biol. 2012 Oct;23(8):890-6. doi: 10.1016/j.semcdb.2012.08.008. Epub 2012 Aug 31. Review.

PMID:
22960184
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Planar cell polarity effector gene Intu regulates cell fate-specific differentiation of keratinocytes through the primary cilia.

Dai D, Li L, Huebner A, Zeng H, Guevara E, Claypool DJ, Liu A, Chen J.

Cell Death Differ. 2013 Jan;20(1):130-8. doi: 10.1038/cdd.2012.104. Epub 2012 Aug 31.

PMID:
22935613
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Podocyte-specific loss of Cdc42 leads to congenital nephropathy.

Scott RP, Hawley SP, Ruston J, Du J, Brakebusch C, Jones N, Pawson T.

J Am Soc Nephrol. 2012 Jul;23(7):1149-54. doi: 10.1681/ASN.2011121206. Epub 2012 Apr 19.

PMID:
22518006
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Cdc42 and Rab8a are critical for intestinal stem cell division, survival, and differentiation in mice.

Sakamori R, Das S, Yu S, Feng S, Stypulkowski E, Guan Y, Douard V, Tang W, Ferraris RP, Harada A, Brakebusch C, Guo W, Gao N.

J Clin Invest. 2012 Mar 1;122(3):1052-65. doi: 10.1172/JCI60282. Epub 2012 Feb 22.

PMID:
22354172
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

The Rho GTPase Cdc42 is required for primary mammary epithelial cell morphogenesis in vitro.

Bray K, Brakebusch C, Vargo-Gogola T.

Small GTPases. 2011 Sep;2(5):247-258. Epub 2011 Sep 1.

PMID:
22292127
[PubMed]
Free PMC Article
14.

Patterning skin by planar cell polarity: the multi-talented hair designer.

Chen J, Chuong CM.

Exp Dermatol. 2012 Feb;21(2):81-5. doi: 10.1111/j.1600-0625.2011.01425.x.

PMID:
22229440
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Retinal degeneration modulates intracellular localization of CDC42 in photoreceptors.

Heynen SR, Tanimoto N, Joly S, Seeliger MW, Samardzija M, Grimm C.

Mol Vis. 2011;17:2934-46. Epub 2011 Nov 15.

PMID:
22128240
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

The small GTPase Cdc42 interacts with Niemann-Pick C1-like 1 (NPC1L1) and controls its movement from endocytic recycling compartment to plasma membrane in a cholesterol-dependent manner.

Xie C, Li N, Chen ZJ, Li BL, Song BL.

J Biol Chem. 2011 Oct 14;286(41):35933-42. doi: 10.1074/jbc.M111.270199. Epub 2011 Aug 15.

PMID:
21844200
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Cdc42 controls vascular network assembly through protein kinase Cι during embryonic vasculogenesis.

Qi Y, Liu J, Wu X, Brakebusch C, Leitges M, Han Y, Corbett SA, Lowry SF, Graham AM, Li S.

Arterioscler Thromb Vasc Biol. 2011 Aug;31(8):1861-70. doi: 10.1161/ATVBAHA.111.230144. Epub 2011 Jun 9.

PMID:
21659643
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Gain-of-function mutations of ARHGAP31, a Cdc42/Rac1 GTPase regulator, cause syndromic cutis aplasia and limb anomalies.

Southgate L, Machado RD, Snape KM, Primeau M, Dafou D, Ruddy DM, Branney PA, Fisher M, Lee GJ, Simpson MA, He Y, Bradshaw TY, Blaumeiser B, Winship WS, Reardon W, Maher ER, FitzPatrick DR, Wuyts W, Zenker M, Lamarche-Vane N, Trembath RC.

Am J Hum Genet. 2011 May 13;88(5):574-85. doi: 10.1016/j.ajhg.2011.04.013.

PMID:
21565291
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Cdc42 in oncogenic transformation, invasion, and tumorigenesis.

Stengel K, Zheng Y.

Cell Signal. 2011 Sep;23(9):1415-23. doi: 10.1016/j.cellsig.2011.04.001. Epub 2011 Apr 16. Review.

PMID:
21515363
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Does GSK-3 provide a shortcut for PI3K activation of Wnt signalling?

Voskas D, Ling LS, Woodgett JR.

F1000 Biol Rep. 2010 Nov 24;2:82. doi: 10.3410/B2-82.

PMID:
21283602
[PubMed]
Free PMC Article

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