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Items: 11


Overcoming Therapeutic Resistance in HER2-Positive Breast Cancers with CDK4/6 Inhibitors.

Goel S, Wang Q, Watt AC, Tolaney SM, Dillon DA, Li W, Ramm S, Palmer AC, Yuzugullu H, Varadan V, Tuck D, Harris LN, Wong KK, Liu XS, Sicinski P, Winer EP, Krop IE, Zhao JJ.

Cancer Cell. 2016 Mar 14;29(3):255-69. doi: 10.1016/j.ccell.2016.02.006.


CDK4/6 and IGF1 receptor inhibitors synergize to suppress the growth of p16INK4A-deficient pancreatic cancers.

Heilmann AM, Perera RM, Ecker V, Nicolay BN, Bardeesy N, Benes CH, Dyson NJ.

Cancer Res. 2014 Jul 15;74(14):3947-58. doi: 10.1158/0008-5472.CAN-13-2923. Epub 2014 Jul 1.


A kinase-independent function of CDK6 links the cell cycle to tumor angiogenesis.

Kollmann K, Heller G, Schneckenleithner C, Warsch W, Scheicher R, Ott RG, Schäfer M, Fajmann S, Schlederer M, Schiefer AI, Reichart U, Mayerhofer M, Hoeller C, Zöchbauer-Müller S, Kerjaschki D, Bock C, Kenner L, Hoefler G, Freissmuth M, Green AR, Moriggl R, Busslinger M, Malumbres M, Sexl V.

Cancer Cell. 2013 Aug 12;24(2):167-81. doi: 10.1016/j.ccr.2013.07.012.


MEK drives cyclin D1 hyperelevation during geroconversion.

Leontieva OV, Demidenko ZN, Blagosklonny MV.

Cell Death Differ. 2013 Sep;20(9):1241-9. doi: 10.1038/cdd.2013.86. Epub 2013 Jul 12.


Identification of new cell size control genes in S. cerevisiae.

Dungrawala H, Hua H, Wright J, Abraham L, Kasemsri T, McDowell A, Stilwell J, Schneider BL.

Cell Div. 2012 Dec 12;7(1):24. doi: 10.1186/1747-1028-7-24.


Hyper-mitogenic drive coexists with mitotic incompetence in senescent cells.

Leontieva OV, Lenzo F, Demidenko ZN, Blagosklonny MV.

Cell Cycle. 2012 Dec 15;11(24):4642-9. doi: 10.4161/cc.22937. Epub 2012 Nov 27.


Pancreatic endocrine tumors: expression profiling evidences a role for AKT-mTOR pathway.

Missiaglia E, Dalai I, Barbi S, Beghelli S, Falconi M, della Peruta M, Piemonti L, Capurso G, Di Florio A, delle Fave G, Pederzoli P, Croce CM, Scarpa A.

J Clin Oncol. 2010 Jan 10;28(2):245-55. doi: 10.1200/JCO.2008.21.5988. Epub 2009 Nov 16.


PKR, the double stranded RNA-dependent protein kinase as a critical target in Alzheimer's disease.

Morel M, Couturier J, Lafay-Chebassier C, Paccalin M, Page G.

J Cell Mol Med. 2009 Aug;13(8A):1476-88. doi: 10.1111/j.1582-4934.2009.00849.x. Epub 2009 Jul 7. Review.


The TSC1-TSC2 complex: a molecular switchboard controlling cell growth.

Huang J, Manning BD.

Biochem J. 2008 Jun 1;412(2):179-90. doi: 10.1042/BJ20080281. Review.


WD40 protein FBW5 promotes ubiquitination of tumor suppressor TSC2 by DDB1-CUL4-ROC1 ligase.

Hu J, Zacharek S, He YJ, Lee H, Shumway S, Duronio RJ, Xiong Y.

Genes Dev. 2008 Apr 1;22(7):866-71. doi: 10.1101/gad.1624008.


Regulation of CDK4.

Bockstaele L, Coulonval K, Kooken H, Paternot S, Roger PP.

Cell Div. 2006 Nov 8;1:25.

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