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Everolimus downregulates estrogen receptor and induces autophagy in aromatase inhibitor-resistant breast cancer cells.

Lui A, New J, Ogony J, Thomas S, Lewis-Wambi J.

BMC Cancer. 2016 Jul 16;16:487. doi: 10.1186/s12885-016-2490-z.


Solamargine triggers cellular necrosis selectively in different types of human melanoma cancer cells through extrinsic lysosomal mitochondrial death pathway.

Al Sinani SS, Eltayeb EA, Coomber BL, Adham SA.

Cancer Cell Int. 2016 Feb 17;16:11. doi: 10.1186/s12935-016-0287-4. eCollection 2016.


Single-Molecule Sequencing Reveals Estrogen-Regulated Clinically Relevant lncRNAs in Breast Cancer.

Jonsson P, Coarfa C, Mesmar F, Raz T, Rajapakshe K, Thompson JF, Gunaratne PH, Williams C.

Mol Endocrinol. 2015 Nov;29(11):1634-45. doi: 10.1210/me.2015-1153. Epub 2015 Oct 1.


Integration of Downstream Signals of Insulin-like Growth Factor-1 Receptor by Endoplasmic Reticulum Stress for Estrogen-Induced Growth or Apoptosis in Breast Cancer Cells.

Fan P, Cunliffe HE, Maximov PY, Agboke FA, McDaniel RE, Zou X, Ramos P, Russell ML, Jordan VC.

Mol Cancer Res. 2015 Oct;13(10):1367-76. doi: 10.1158/1541-7786.MCR-14-0494. Epub 2015 Jun 26.


The Impact of Endometriosis across the Lifespan of Women: Foreseeable Research and Therapeutic Prospects.

Hughes CL, Foster WG, Agarwal SK.

Biomed Res Int. 2015;2015:158490. doi: 10.1155/2015/158490. Epub 2015 May 6. Review.


The molecular, cellular and clinical consequences of targeting the estrogen receptor following estrogen deprivation therapy.

Fan P, Maximov PY, Curpan RF, Abderrahman B, Jordan VC.

Mol Cell Endocrinol. 2015 Dec 15;418 Pt 3:245-63. doi: 10.1016/j.mce.2015.06.004. Epub 2015 Jun 5. Review.


High Prevalence of the BIM Deletion Polymorphism in Young Female Breast Cancer in an East Asian Country.

Lin CH, Shen CY, Lee JH, Huang CS, Yang CH, Kuo WH, Chang DY, Hsiung CN, Kuo KT, Chen WW, Chen IC, Wu PF, Kuo SH, Chen CJ, Lu YS, Cheng AL.

PLoS One. 2015 Apr 24;10(4):e0124908. doi: 10.1371/journal.pone.0124908. eCollection 2015.


Mechanisms of endocrine resistance in breast cancer: an overview of the proposed roles of noncoding RNA.

Hayes EL, Lewis-Wambi JS.

Breast Cancer Res. 2015 Mar 17;17:40. doi: 10.1186/s13058-015-0542-y. Review.


Targeting interferon response genes sensitizes aromatase inhibitor resistant breast cancer cells to estrogen-induced cell death.

Choi HJ, Lui A, Ogony J, Jan R, Sims PJ, Lewis-Wambi J.

Breast Cancer Res. 2015 Jan 15;17:6. doi: 10.1186/s13058-014-0506-7.


The new biology of estrogen-induced apoptosis applied to treat and prevent breast cancer.

Jordan VC.

Endocr Relat Cancer. 2015 Feb;22(1):R1-31. doi: 10.1530/ERC-14-0448. Epub 2014 Oct 22. Review.


Linking estrogen-induced apoptosis with decreases in mortality following long-term adjuvant tamoxifen therapy.

Jordan VC.

J Natl Cancer Inst. 2014 Sep 30;106(11). pii: dju296. doi: 10.1093/jnci/dju296. Print 2014 Nov.


Identification of gene regulation patterns underlying both oestrogen- and tamoxifen-stimulated cell growth through global gene expression profiling in breast cancer cells.

Fan P, Cunliffe HE, Griffith OL, Agboke FA, Ramos P, Gray JW, Jordan VC.

Eur J Cancer. 2014 Nov;50(16):2877-86. doi: 10.1016/j.ejca.2014.08.010. Epub 2014 Sep 15.


A molecular model for the mechanism of acquired tamoxifen resistance in breast cancer.

Fan P, Agboke FA, Cunliffe HE, Ramos P, Jordan VC.

Eur J Cancer. 2014 Nov;50(16):2866-76. doi: 10.1016/j.ejca.2014.08.011. Epub 2014 Sep 6.


Proven value of translational research with appropriate animal models to advance breast cancer treatment and save lives: the tamoxifen tale.

Jordan VC.

Br J Clin Pharmacol. 2015 Feb;79(2):254-67. doi: 10.1111/bcp.12440. No abstract available.


Differences in the rate of oestrogen-induced apoptosis in breast cancer by oestradiol and the triphenylethylene bisphenol.

Obiorah IE, Jordan VC.

Br J Pharmacol. 2014 Sep;171(17):4062-72. doi: 10.1111/bph.12762.


Defining the conformation of the estrogen receptor complex that controls estrogen-induced apoptosis in breast cancer.

Obiorah I, Sengupta S, Curpan R, Jordan VC.

Mol Pharmacol. 2014 May;85(5):789-99. doi: 10.1124/mol.113.089250. Epub 2014 Mar 7.


Mechanisms underlying differential response to estrogen-induced apoptosis in long-term estrogen-deprived breast cancer cells.

Sweeney EE, Fan P, Jordan VC.

Int J Oncol. 2014 May;44(5):1529-38. doi: 10.3892/ijo.2014.2329. Epub 2014 Mar 6.


Delayed triggering of oestrogen induced apoptosis that contrasts with rapid paclitaxel-induced breast cancer cell death.

Obiorah I, Sengupta S, Fan P, Jordan VC.

Br J Cancer. 2014 Mar 18;110(6):1488-96. doi: 10.1038/bjc.2014.50. Epub 2014 Feb 18.

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