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Clinical significance of T cell metabolic reprogramming in cancer.

Herbel C, Patsoukis N, Bardhan K, Seth P, Weaver JD, Boussiotis VA.

Clin Transl Med. 2016 Dec;5(1):29. doi: 10.1186/s40169-016-0110-9. Epub 2016 Aug 10. Review.


Effects of glucose on lactose synthesis in mammary epithelial cells from dairy cow.

Lin Y, Sun X, Hou X, Qu B, Gao X, Li Q.

BMC Vet Res. 2016 May 26;12:81. doi: 10.1186/s12917-016-0704-x.


AKT1E¹⁷K Is Oncogenic in Mouse Lung and Cooperates with Chemical Carcinogens in Inducing Lung Cancer.

Malanga D, Belmonte S, Colelli F, Scarfò M, De Marco C, Oliveira DM, Mirante T, Camastra C, Gagliardi M, Rizzuto A, Mignogna C, Paciello O, Papparella S, Fagman H, Viglietto G.

PLoS One. 2016 Feb 9;11(2):e0147334. doi: 10.1371/journal.pone.0147334. eCollection 2016.


Differentiation of human neuroblastoma cells toward the osteogenic lineage by mTOR inhibitor.

Carpentieri A, Cozzoli E, Scimeca M, Bonanno E, Sardanelli AM, Gambacurta A.

Cell Death Dis. 2015 Nov 12;6:e1974. doi: 10.1038/cddis.2015.244. Erratum in: Cell Death Dis. 2016;7:e2202.


Benzofuroxan derivatives N-Br and N-I induce intrinsic apoptosis in melanoma cells by regulating AKT/BIM signaling and display anti metastatic activity in vivo.

Farias CF, Massaoka MH, Girola N, Azevedo RA, Ferreira AK, Jorge SD, Tavares LC, Figueiredo CR, Travassos LR.

BMC Cancer. 2015 Oct 27;15:807. doi: 10.1186/s12885-015-1835-3.


Hyperpolarized (13)C Magnetic Resonance and Its Use in Metabolic Assessment of Cultured Cells and Perfused Organs.

Lumata L, Yang C, Ragavan M, Carpenter N, DeBerardinis RJ, Merritt ME.

Methods Enzymol. 2015;561:73-106. doi: 10.1016/bs.mie.2015.04.006. Epub 2015 Jun 14. Review.


Ubl4A is required for insulin-induced Akt plasma membrane translocation through promotion of Arp2/3-dependent actin branching.

Zhao Y, Lin Y, Zhang H, Mañas A, Tang W, Zhang Y, Wu D, Lin A, Xiang J.

Proc Natl Acad Sci U S A. 2015 Aug 4;112(31):9644-9. doi: 10.1073/pnas.1508647112. Epub 2015 Jul 20.


Everolimus combined with gefitinib in patients with metastatic castration-resistant prostate cancer: Phase 1/2 results and signaling pathway implications.

Rathkopf DE, Larson SM, Anand A, Morris MJ, Slovin SF, Shaffer DR, Heller G, Carver B, Rosen N, Scher HI.

Cancer. 2015 Nov 1;121(21):3853-61. doi: 10.1002/cncr.29578. Epub 2015 Jul 15.


Mutant AKT1-E17K is oncogenic in lung epithelial cells.

De Marco C, Malanga D, Rinaldo N, De Vita F, Scrima M, Lovisa S, Fabris L, Carriero MV, Franco R, Rizzuto A, Baldassarre G, Viglietto G.

Oncotarget. 2015 Nov 24;6(37):39634-50. doi: 10.18632/oncotarget.4022.


Activating PIK3CA mutations coexist with BRAF or NRAS mutations in a limited fraction of melanomas.

Manca A, Lissia A, Capone M, Ascierto PA, Botti G, Caracò C, Stanganelli I, Colombino M, Sini M, Cossu A, Palmieri G.

J Transl Med. 2015 Jan 28;13:37. doi: 10.1186/s12967-015-0401-8.


Klf5 deletion promotes Pten deletion-initiated luminal-type mouse prostate tumors through multiple oncogenic signaling pathways.

Xing C, Ci X, Sun X, Fu X, Zhang Z, Dong EN, Hao ZZ, Dong JT.

Neoplasia. 2014 Nov 20;16(11):883-99. doi: 10.1016/j.neo.2014.09.006. eCollection 2014 Nov.


The PTEN/PI3K/AKT Pathway in vivo, Cancer Mouse Models.

Carnero A, Paramio JM.

Front Oncol. 2014 Sep 23;4:252. doi: 10.3389/fonc.2014.00252. eCollection 2014. Review.


Inhibition of fatty acid synthase induces pro-survival Akt and ERK signaling in K-Ras-driven cancer cells.

Yellen P, Foster DA.

Cancer Lett. 2014 Oct 28;353(2):258-63. doi: 10.1016/j.canlet.2014.07.027. Epub 2014 Jul 30.


Rictor is required for early B cell development in bone marrow.

Zhang Y, Hu T, Hua C, Gu J, Zhang L, Hao S, Liang H, Wang X, Wang W, Xu J, Liu H, Liu B, Cheng T, Yuan W.

PLoS One. 2014 Aug 1;9(8):e103970. doi: 10.1371/journal.pone.0103970. eCollection 2014.


Natural allelic variations in glutathione peroxidase-1 affect its subcellular localization and function.

Bera S, Weinberg F, Ekoue DN, Ansenberger-Fricano K, Mao M, Bonini MG, Diamond AM.

Cancer Res. 2014 Sep 15;74(18):5118-26. doi: 10.1158/0008-5472.CAN-14-0660. Epub 2014 Jul 21.


Akt-dependent activation of mTORC1 complex involves phosphorylation of mTOR (mammalian target of rapamycin) by IκB kinase α (IKKα).

Dan HC, Ebbs A, Pasparakis M, Van Dyke T, Basseres DS, Baldwin AS.

J Biol Chem. 2014 Sep 5;289(36):25227-40. doi: 10.1074/jbc.M114.554881. Epub 2014 Jul 2.


High metastaticgastric and breast cancer cells consume oleic acid in an AMPK dependent manner.

Li S, Zhou T, Li C, Dai Z, Che D, Yao Y, Li L, Ma J, Yang X, Gao G.

PLoS One. 2014 May 13;9(5):e97330. doi: 10.1371/journal.pone.0097330. eCollection 2014.


MR-detectable metabolic consequences of mitogen-activated protein kinase kinase (MEK) inhibition.

Lodi A, Woods SM, Ronen SM.

NMR Biomed. 2014 Jun;27(6):700-8. doi: 10.1002/nbm.3109. Epub 2014 Apr 2.


The role of mitochondria in the development and progression of lung cancer.

Roberts ER, Thomas KJ.

Comput Struct Biotechnol J. 2013 Dec 7;6:e201303019. doi: 10.5936/csbj.201303019. eCollection 2013. Review.

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