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High-Level Expression of Recombinant Bovine Lactoferrin in Pichia pastoris with Antimicrobial Activity.

Iglesias-Figueroa B, Valdiviezo-Godina N, Siqueiros-Cendón T, Sinagawa-García S, Arévalo-Gallegos S, Rascón-Cruz Q.

Int J Mol Sci. 2016 Jun 9;17(6). pii: E902. doi: 10.3390/ijms17060902.


Lactoferrin Enhanced Apoptosis and Protected Against Thioacetamide-Induced Liver Fibrosis in Rats.

Hessin A, Hegazy R, Hassan A, Yassin N, Kenawy S.

Open Access Maced J Med Sci. 2015 Jun 15;3(2):195-201. doi: 10.3889/oamjms.2015.038. Epub 2015 Mar 31.


Renoprotective Effect of Lactoferrin against Chromium-Induced Acute Kidney Injury in Rats: Involvement of IL-18 and IGF-1 Inhibition.

Hegazy R, Salama A, Mansour D, Hassan A.

PLoS One. 2016 Mar 18;11(3):e0151486. doi: 10.1371/journal.pone.0151486. eCollection 2016.


PFR peptide, one of the antimicrobial peptides identified from the derivatives of lactoferrin, induces necrosis in leukemia cells.

Lu Y, Zhang TF, Shi Y, Zhou HW, Chen Q, Wei BY, Wang X, Yang TX, Chinn YE, Kang J, Fu CY.

Sci Rep. 2016 Feb 10;6:20823. doi: 10.1038/srep20823.


Vibrio Iron Transport: Evolutionary Adaptation to Life in Multiple Environments.

Payne SM, Mey AR, Wyckoff EE.

Microbiol Mol Biol Rev. 2015 Dec 9;80(1):69-90. doi: 10.1128/MMBR.00046-15. Print 2016 Mar. Review.


A Tetrameric Peptide Derived from Bovine Lactoferricin Exhibits Specific Cytotoxic Effects against Oral Squamous-Cell Carcinoma Cell Lines.

Solarte VA, Rosas JE, Rivera ZJ, Arango-Rodríguez ML, García JE, Vernot JP.

Biomed Res Int. 2015;2015:630179. doi: 10.1155/2015/630179. Epub 2015 Nov 2.


Lactoferrin Expression in Human and Murine Ocular Tissue.

Rageh AA, Ferrington DA, Roehrich H, Yuan C, Terluk MR, Nelson EF, Montezuma SR.

Curr Eye Res. 2016 Jul;41(7):883-9. doi: 10.3109/02713683.2015.1075220. Epub 2015 Oct 2.


Antimicrobial activity of synthetic cationic peptides and lipopeptides derived from human lactoferricin against Pseudomonas aeruginosa planktonic cultures and biofilms.

Sánchez-Gómez S, Ferrer-Espada R, Stewart PS, Pitts B, Lohner K, Martínez de Tejada G.

BMC Microbiol. 2015 Jul 7;15:137. doi: 10.1186/s12866-015-0473-x.


Antimicrobial peptide resistance in Neisseria meningitidis.

Tzeng YL, Stephens DS.

Biochim Biophys Acta. 2015 Nov;1848(11 Pt B):3026-31. doi: 10.1016/j.bbamem.2015.05.006. Epub 2015 May 19. Review.


Tumor regression following intravenous administration of lactoferrin- and lactoferricin-bearing dendriplexes.

Lim LY, Koh PY, Somani S, Al Robaian M, Karim R, Yean YL, Mitchell J, Tate RJ, Edrada-Ebel R, Blatchford DR, Mullin M, Dufès C.

Nanomedicine. 2015 Aug;11(6):1445-54. doi: 10.1016/j.nano.2015.04.006. Epub 2015 Apr 29.


Influence of Dimerization of Lipopeptide Laur-Orn-Orn-Cys-NH2 and an N-terminal Peptide of Human Lactoferricin on Biological Activity.

Kamysz E, Sikorska E, Dawgul M, Tyszkowski R, Kamysz W.

Int J Pept Res Ther. 2015;21:39-46. Epub 2014 Aug 21.


Illness in breastfeeding infants relates to concentration of lactoferrin and secretory Immunoglobulin A in mother's milk.

Breakey AA, Hinde K, Valeggia CR, Sinofsky A, Ellison PT.

Evol Med Public Health. 2015 Jan 20;2015(1):21-31. doi: 10.1093/emph/eov002.


Clearance of Escherichia coli O157:H7 infection in calves by rectal administration of bovine lactoferrin.

Kieckens E, Rybarczyk J, De Zutter L, Duchateau L, Vanrompay D, Cox E.

Appl Environ Microbiol. 2015 Mar;81(5):1644-51. doi: 10.1128/AEM.03724-14. Epub 2014 Dec 19.


Therapeutic interventions in sepsis: current and anticipated pharmacological agents.

Shukla P, Rao GM, Pandey G, Sharma S, Mittapelly N, Shegokar R, Mishra PR.

Br J Pharmacol. 2014 Nov;171(22):5011-31. doi: 10.1111/bph.12829. Epub 2014 Sep 5. Review.


Killing of melanoma cells and their metastases by human lactoferricin derivatives requires interaction with the cancer marker phosphatidylserine.

Riedl S, Rinner B, Schaider H, Lohner K, Zweytick D.

Biometals. 2014 Oct;27(5):981-97. doi: 10.1007/s10534-014-9749-0. Epub 2014 May 18.


Coupling Mass Spectrometry-Based "Omic" Sciences with Bioguided Processing to Unravel Milk's Hidden Bioactivities.

Dallas DC, Lee H, Parc AL, de Moura Bell JM, Barile D.

J Adv Dairy Res. 2013 Jul 24;1(2):104.


Immunomodulatory effects of lactoferrin.

Siqueiros-Cendón T, Arévalo-Gallegos S, Iglesias-Figueroa BF, García-Montoya IA, Salazar-Martínez J, Rascón-Cruz Q.

Acta Pharmacol Sin. 2014 May;35(5):557-66. doi: 10.1038/aps.2013.200. Review.


Killing of Mycobacterium avium by lactoferricin peptides: improved activity of arginine- and D-amino-acid-containing molecules.

Silva T, Magalhães B, Maia S, Gomes P, Nazmi K, Bolscher JG, Rodrigues PN, Bastos M, Gomes MS.

Antimicrob Agents Chemother. 2014 Jun;58(6):3461-7. doi: 10.1128/AAC.02728-13. Epub 2014 Apr 7.


Therapeutic potential of the antimicrobial peptide OH-CATH30 for antibiotic-resistant Pseudomonas aeruginosa keratitis.

Li SA, Liu J, Xiang Y, Wang YJ, Lee WH, Zhang Y.

Antimicrob Agents Chemother. 2014 Jun;58(6):3144-50. doi: 10.1128/AAC.00095-14. Epub 2014 Mar 17.


Penetration of milk-derived antimicrobial peptides into phospholipid monolayers as model biomembranes.

Barzyk W, Rogalska E, Więcław-Czapla K.

Biochem Res Int. 2013;2013:914540. doi: 10.1155/2013/914540. Epub 2013 Dec 17.

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