Display Settings:

Format
Items per page
Sort by

Send to:

Choose Destination

Results: 1 to 20 of 51

1.

Elucidating the specificity of non-heparin-based conformational activators of antithrombin for factor Xa inhibition.

Rashid Q, Abid M, Jairajpuri MA.

J Nat Sci Biol Med. 2014 Jan;5(1):36-42. doi: 10.4103/0976-9668.127282.

PMID:
24678194
[PubMed]
Free PMC Article
2.

Heparin reduces neuroinflammation and transsynaptic neuronal apoptosis in a model of subarachnoid hemorrhage.

Simard JM, Tosun C, Ivanova S, Kurland DB, Hong C, Radecki L, Gisriel C, Mehta R, Schreibman D, Gerzanich V.

Transl Stroke Res. 2012 Jul;3(Suppl 1):155-65. doi: 10.1007/s12975-012-0166-9. Epub 2012 Apr 14.

PMID:
22707992
[PubMed]
Free PMC Article
3.

Chemoenzymatic synthesis of the next generation of ultralow MW heparin therapeutics.

Masuko S, Linhardt RJ.

Future Med Chem. 2012 Mar;4(3):289-96. doi: 10.4155/fmc.11.185. Review.

PMID:
22393937
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Pentosan polysulfate increases affinity between ADAMTS-5 and TIMP-3 through formation of an electrostatically driven trimolecular complex.

Troeberg L, Mulloy B, Ghosh P, Lee MH, Murphy G, Nagase H.

Biochem J. 2012 Apr 1;443(1):307-15. doi: 10.1042/BJ20112159.

PMID:
22299597
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Specificity and selectivity profile of EP217609: a new neutralizable dual-action anticoagulant that targets thrombin and factor Xa.

Olson ST, Swanson R, Petitou M.

Blood. 2012 Mar 8;119(10):2187-95. doi: 10.1182/blood-2011-09-381764. Epub 2011 Dec 5.

PMID:
22144183
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Anticoagulants and the propagation phase of thrombin generation.

Orfeo T, Gissel M, Butenas S, Undas A, Brummel-Ziedins KE, Mann KG.

PLoS One. 2011;6(11):e27852. doi: 10.1371/journal.pone.0027852. Epub 2011 Nov 18.

PMID:
22125631
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Designing nonsaccharide, allosteric activators of antithrombin for accelerated inhibition of factor Xa.

Al-Horani RA, Liang A, Desai UR.

J Med Chem. 2011 Sep 8;54(17):6125-38. doi: 10.1021/jm2008387. Epub 2011 Aug 12.

PMID:
21800826
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

New anticoagulants: how to deal with treatment failure and bleeding complications.

Kazmi RS, Lwaleed BA.

Br J Clin Pharmacol. 2011 Oct;72(4):593-603. doi: 10.1111/j.1365-2125.2011.04060.x. Review.

PMID:
21752066
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Heparin is a major activator of the anticoagulant serpin, protein Z-dependent protease inhibitor.

Huang X, Rezaie AR, Broze GJ Jr, Olson ST.

J Biol Chem. 2011 Mar 18;286(11):8740-51. doi: 10.1074/jbc.M110.188375. Epub 2011 Jan 10.

PMID:
21220417
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Hormonal contraception and thrombotic risk: a multidisciplinary approach.

Trenor CC 3rd, Chung RJ, Michelson AD, Neufeld EJ, Gordon CM, Laufer MR, Emans SJ.

Pediatrics. 2011 Feb;127(2):347-57. doi: 10.1542/peds.2010-2221. Epub 2011 Jan 3. Review.

PMID:
21199853
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Structural and functional characterization of a highly specific serpin in the insect innate immunity.

Park SH, Jiang R, Piao S, Zhang B, Kim EH, Kwon HM, Jin XL, Lee BL, Ha NC.

J Biol Chem. 2011 Jan 14;286(2):1567-75. doi: 10.1074/jbc.M110.144006. Epub 2010 Nov 3.

PMID:
21047786
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Kinetic evidence that allosteric activation of antithrombin by heparin is mediated by two sequential conformational changes.

Schedin-Weiss S, Richard B, Olson ST.

Arch Biochem Biophys. 2010 Dec 15;504(2):169-76. doi: 10.1016/j.abb.2010.08.021. Epub 2010 Sep 15.

PMID:
20816747
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Chemical Sulfation of Small Molecules - Advances and Challenges.

Al-Horani RA, Desai UR.

Tetrahedron. 2010 Apr 17;66(16):2907-2918. No abstract available.

PMID:
20689724
[PubMed]
Free PMC Article
14.

Molecular mechanisms of antithrombin-heparin regulation of blood clotting proteinases. A paradigm for understanding proteinase regulation by serpin family protein proteinase inhibitors.

Olson ST, Richard B, Izaguirre G, Schedin-Weiss S, Gettins PG.

Biochimie. 2010 Nov;92(11):1587-96. doi: 10.1016/j.biochi.2010.05.011. Epub 2010 Jun 2. Review.

PMID:
20685328
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Natural and synthetic inhibitors of kallikrein-related peptidases (KLKs).

Goettig P, Magdolen V, Brandstetter H.

Biochimie. 2010 Nov;92(11):1546-67. doi: 10.1016/j.biochi.2010.06.022. Epub 2010 Jul 6. Review.

PMID:
20615447
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Anticoagulation by factor Xa inhibitors.

Orfeo T, Butenas S, Brummel-Ziedins KE, Gissel M, Mann KG.

J Thromb Haemost. 2010 Aug;8(8):1745-53. doi: 10.1111/j.1538-7836.2010.03917.x. Epub 2010 May 21.

PMID:
20492473
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Pathophysiology, management and treatment of smoke inhalation injury.

Rehberg S, Maybauer MO, Enkhbaatar P, Maybauer DM, Yamamoto Y, Traber DL.

Expert Rev Respir Med. 2009 Jun 1;3(3):283-297.

PMID:
20161170
[PubMed]
Free PMC Article
18.

Activation of antithrombin as a factor IXa and Xa inhibitor involves mitigation of repression rather than positive enhancement.

Gettins PG, Olson ST.

FEBS Lett. 2009 Nov 3;583(21):3397-400. doi: 10.1016/j.febslet.2009.10.005. Epub 2009 Oct 9.

PMID:
19818773
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Role of P2 glycine in determining the specificity of antithrombin reaction with coagulation proteases.

Yang L, Qureshi SH, Manithody C, Rezaie AR.

Biochem Biophys Res Commun. 2009 Nov 6;389(1):162-7. doi: 10.1016/j.bbrc.2009.08.118. Epub 2009 Aug 26.

PMID:
19715676
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

The signature 3-O-sulfo group of the anticoagulant heparin sequence is critical for heparin binding to antithrombin but is not required for allosteric activation.

Richard B, Swanson R, Olson ST.

J Biol Chem. 2009 Oct 2;284(40):27054-64. doi: 10.1074/jbc.M109.029892. Epub 2009 Aug 6.

PMID:
19661062
[PubMed - indexed for MEDLINE]
Free PMC Article

Display Settings:

Format
Items per page
Sort by

Send to:

Choose Destination

Supplemental Content

Write to the Help Desk