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Results: 1 to 20 of 26

Cited In for PubMed (Select 16051857)


Impacts of humanized mouse models on the investigation of HIV-1 infection: illuminating the roles of viral accessory proteins in vivo.

Yamada E, Yoshikawa R, Nakano Y, Misawa N, Koyanagi Y, Sato K.

Viruses. 2015 Mar 23;7(3):1373-90. doi: 10.3390/v7031373. Review.


HIV-1 Nef and Vpu are functionally redundant broad-spectrum modulators of cell surface receptors, including tetraspanins.

Haller C, Müller B, Fritz JV, Lamas-Murua M, Stolp B, Pujol FM, Keppler OT, Fackler OT.

J Virol. 2014 Dec;88(24):14241-57. doi: 10.1128/JVI.02333-14. Epub 2014 Oct 1.


Host factors determine differential disease progression after infection with nef-deleted simian immunodeficiency virus.

Sopper S, Mätz-Rensing K, Mühl T, Heeney J, Stahl-Hennig C, Sauermann U.

J Gen Virol. 2014 Oct;95(Pt 10):2273-84. doi: 10.1099/vir.0.066563-0. Epub 2014 Jun 13.


Downmodulation of CCR7 by HIV-1 Vpu results in impaired migration and chemotactic signaling within CD4⁺ T cells.

Ramirez PW, Famiglietti M, Sowrirajan B, DePaula-Silva AB, Rodesch C, Barker E, Bosque A, Planelles V.

Cell Rep. 2014 Jun 26;7(6):2019-30. doi: 10.1016/j.celrep.2014.05.015. Epub 2014 Jun 5.


HIV-1 Nef down-modulates C-C and C-X-C chemokine receptors via ubiquitin and ubiquitin-independent mechanism.

Chandrasekaran P, Moore V, Buckley M, Spurrier J, Kehrl JH, Venkatesan S.

PLoS One. 2014 Jan 29;9(1):e86998. doi: 10.1371/journal.pone.0086998. eCollection 2014.


Primate lentiviral Nef proteins deregulate T-cell development by multiple mechanisms.

Van Nuffel A, Ariën KK, Stove V, Schindler M, O'Neill E, Schmökel J, Van de Walle I, Naessens E, Vanderstraeten H, Van Landeghem K, Taghon T, Pulkkinen K, Saksela K, Garcia JV, Fackler OT, Kirchhoff F, Verhasselt B.

Retrovirology. 2013 Nov 15;10:137. doi: 10.1186/1742-4690-10-137.


In vivo analysis of highly conserved Nef activities in HIV-1 replication and pathogenesis.

Watkins RL, Zou W, Denton PW, Krisko JF, Foster JL, Garcia JV.

Retrovirology. 2013 Oct 30;10:125. doi: 10.1186/1742-4690-10-125.


HIV-1 Nef impairs heterotrimeric G-protein signaling by targeting Gα(i2) for degradation through ubiquitination.

Chandrasekaran P, Buckley M, Moore V, Wang LQ, Kehrl JH, Venkatesan S.

J Biol Chem. 2012 Nov 30;287(49):41481-98. doi: 10.1074/jbc.M112.361782. Epub 2012 Oct 15.


Identification of a highly conserved valine-glycine-phenylalanine amino acid triplet required for HIV-1 Nef function.

Meuwissen PJ, Stolp B, Iannucci V, Vermeire J, Naessens E, Saksela K, Geyer M, Vanham G, Arien KK, Fackler OT, Verhasselt B.

Retrovirology. 2012 Apr 27;9:34. doi: 10.1186/1742-4690-9-34.


One protein to rule them all: modulation of cell surface receptors and molecules by HIV Nef.

Landi A, Iannucci V, Nuffel AV, Meuwissen P, Verhasselt B.

Curr HIV Res. 2011 Oct;9(7):496-504. Review.


The presence of a vpu gene and the lack of Nef-mediated downmodulation of T cell receptor-CD3 are not always linked in primate lentiviruses.

Schmökel J, Sauter D, Schindler M, Leendertz FH, Bailes E, Dazza MC, Saragosti S, Bibollet-Ruche F, Peeters M, Hahn BH, Kirchhoff F.

J Virol. 2011 Jan;85(2):742-52. doi: 10.1128/JVI.02087-10. Epub 2010 Nov 10.


HIV Type 1 Nef is released from infected cells in CD45(+) microvesicles and is present in the plasma of HIV-infected individuals.

Raymond AD, Campbell-Sims TC, Khan M, Lang M, Huang MB, Bond VC, Powell MD.

AIDS Res Hum Retroviruses. 2011 Feb;27(2):167-78. doi: 10.1089/aid.2009.0170. Epub 2010 Oct 21.


Counteraction of HLA-C-mediated immune control of HIV-1 by Nef.

Specht A, Telenti A, Martinez R, Fellay J, Bailes E, Evans DT, Carrington M, Hahn BH, Goldstein DB, Kirchhoff F.

J Virol. 2010 Jul;84(14):7300-11. doi: 10.1128/JVI.00619-10. Epub 2010 May 12.


Molecular Mechanisms of Neurodegenerative Diseases Induced by Human Retroviruses: A Review.

Irish BP, Khan ZK, Jain P, Nonnemacher MR, Pirrone V, Rahman S, Rajagopalan N, Suchitra JB, Mostoller K, Wigdahl B.

Am J Infect Dis. 2009 Jul 1;5(3):231-258.


The inability to disrupt the immunological synapse between infected human T cells and APCs distinguishes HIV-1 from most other primate lentiviruses.

Arhel N, Lehmann M, Clauss K, Nienhaus GU, Piguet V, Kirchhoff F.

J Clin Invest. 2009 Oct;119(10):2965-75. doi: 10.1172/JCI38994. Epub 2009 Sep 14.


Conservation of Nef function across highly diverse lineages of SIVsmm.

Schmökel J, Li H, Bailes E, Schindler M, Silvestri G, Hahn BH, Apetrei C, Kirchhoff F.

Retrovirology. 2009 Apr 9;6:36. doi: 10.1186/1742-4690-6-36.


Human immunodeficiency virus type 1 Nef incorporation into virions does not increase infectivity.

Laguette N, Benichou S, Basmaciogullari S.

J Virol. 2009 Jan;83(2):1093-104. doi: 10.1128/JVI.01633-08. Epub 2008 Nov 5.


Lentiviral Vpx accessory factor targets VprBP/DCAF1 substrate adaptor for cullin 4 E3 ubiquitin ligase to enable macrophage infection.

Srivastava S, Swanson SK, Manel N, Florens L, Washburn MP, Skowronski J.

PLoS Pathog. 2008 May 9;4(5):e1000059. doi: 10.1371/journal.ppat.1000059.


The Mamu B 17-restricted SIV Nef IW9 to TW9 mutation abrogates correct epitope processing and presentation without loss of replicative fitness.

Minang JT, Trivett MT, Coren LV, Barsov EV, Piatak M Jr, Chertov O, Chertova E, Ott DE, Ohlen C.

Virology. 2008 May 25;375(1):307-14. doi: 10.1016/j.virol.2008.02.005. Epub 2008 Mar 6.


Differential control of CXCR4 and CD4 downregulation by HIV-1 Gag.

Valiathan RR, Resh MD.

Virol J. 2008 Feb 11;5:23. doi: 10.1186/1743-422X-5-23.

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