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Unnatural amino acid photo-crosslinking of the IKs channel complex demonstrates a KCNE1:KCNQ1 stoichiometry of up to 4:4.

Murray CI, Westhoff M, Eldstrom J, Thompson E, Emes R, Fedida D.

Elife. 2016 Jan 23;5. pii: e11815. doi: 10.7554/eLife.11815.


Conformational changes of an ion-channel during gating and emerging electrophysiologic properties: Application of a computational approach to cardiac Kv7.1.

Nekouzadeh A, Rudy Y.

Prog Biophys Mol Biol. 2016 Jan;120(1-3):18-27. doi: 10.1016/j.pbiomolbio.2015.12.014. Epub 2015 Dec 30.


KCNE1 and KCNE3: The yin and yang of voltage-gated K(+) channel regulation.

Abbott GW.

Gene. 2016 Jan 15;576(1 Pt 1):1-13. doi: 10.1016/j.gene.2015.09.059. Epub 2015 Sep 26. Review.


Kcne4 deletion sex- and age-specifically impairs cardiac repolarization in mice.

Crump SM, Hu Z, Kant R, Levy DI, Goldstein SA, Abbott GW.

FASEB J. 2016 Jan;30(1):360-9. doi: 10.1096/fj.15-278754. Epub 2015 Sep 23.


Auxiliary KCNE subunits modulate both homotetrameric Kv2.1 and heterotetrameric Kv2.1/Kv6.4 channels.

David JP, Stas JI, Schmitt N, Bocksteins E.

Sci Rep. 2015 Aug 5;5:12813. doi: 10.1038/srep12813.


Ion Channels in the Heart.

Bartos DC, Grandi E, Ripplinger CM.

Compr Physiol. 2015 Jul 1;5(3):1423-64. doi: 10.1002/cphy.c140069. Review.


The KCNE2 K⁺ channel regulatory subunit: Ubiquitous influence, complex pathobiology.

Abbott GW.

Gene. 2015 Sep 15;569(2):162-72. doi: 10.1016/j.gene.2015.06.061. Epub 2015 Jun 27. Review.


Ion channel macromolecular complexes in cardiomyocytes: roles in sudden cardiac death.

Abriel H, Rougier JS, Jalife J.

Circ Res. 2015 Jun 5;116(12):1971-88. doi: 10.1161/CIRCRESAHA.116.305017. Review.


Stochastic approach to the molecular counting problem in superresolution microscopy.

Rollins GC, Shin JY, Bustamante C, Pressé S.

Proc Natl Acad Sci U S A. 2015 Jan 13;112(2):E110-8. doi: 10.1073/pnas.1408071112. Epub 2014 Dec 22.


Computational modeling reveals key contributions of KCNQ and hERG currents to the malleability of uterine action potentials underpinning labor.

Tong WC, Tribe RM, Smith R, Taggart MJ.

PLoS One. 2014 Dec 4;9(12):e114034. doi: 10.1371/journal.pone.0114034. eCollection 2014.


Modification by KCNE1 variants of the hERG potassium channel response to premature stimulation and to pharmacological inhibition.

Du C, El Harchi A, Zhang H, Hancox JC.

Physiol Rep. 2013 Nov;1(6):e00175. doi: 10.1002/phy2.175. Epub 2013 Nov 29.


[Ca2+]i elevation and oxidative stress induce KCNQ1 protein translocation from the cytosol to the cell surface and increase slow delayed rectifier (IKs) in cardiac myocytes.

Wang Y, Zankov DP, Jiang M, Zhang M, Henderson SC, Tseng GN.

J Biol Chem. 2013 Dec 6;288(49):35358-71. doi: 10.1074/jbc.M113.504746. Epub 2013 Oct 18.


Selective targeting of gain-of-function KCNQ1 mutations predisposing to atrial fibrillation.

Campbell CM, Campbell JD, Thompson CH, Galimberti ES, Darbar D, Vanoye CG, George AL Jr.

Circ Arrhythm Electrophysiol. 2013 Oct;6(5):960-6. doi: 10.1161/CIRCEP.113.000439. Epub 2013 Sep 4.


Molecular determinants of co- and post-translational N-glycosylation of type I transmembrane peptides.

Malaby HL, Kobertz WR.

Biochem J. 2013 Aug 1;453(3):427-34. doi: 10.1042/BJ20130028.


Dynamic subunit stoichiometry confers a progressive continuum of pharmacological sensitivity by KCNQ potassium channels.

Yu H, Lin Z, Mattmann ME, Zou B, Terrenoire C, Zhang H, Wu M, McManus OB, Kass RS, Lindsley CW, Hopkins CR, Li M.

Proc Natl Acad Sci U S A. 2013 May 21;110(21):8732-7. doi: 10.1073/pnas.1300684110. Epub 2013 May 6.


Oestrogen promotes KCNQ1 potassium channel endocytosis and postendocytic trafficking in colonic epithelium.

Rapetti-Mauss R, O'Mahony F, Sepulveda FV, Urbach V, Harvey BJ.

J Physiol. 2013 Jun 1;591(11):2813-31. doi: 10.1113/jphysiol.2013.251678. Epub 2013 Mar 25.


A KCNQ1 mutation causes a high penetrance for familial atrial fibrillation.

Bartos DC, Anderson JB, Bastiaenen R, Johnson JN, Gollob MH, Tester DJ, Burgess DE, Homfray T, Behr ER, Ackerman MJ, Guicheney P, Delisle BP.

J Cardiovasc Electrophysiol. 2013 May;24(5):562-9. doi: 10.1111/jce.12068. Epub 2013 Jan 25.


KCNE gene expression is dependent on the proliferation and mode of activation of leukocytes.

Solé L, Vallejo-Gracia A, Roig SR, Serrano-Albarrás A, Marruecos L, Manils J, Gómez D, Soler C, Felipe A.

Channels (Austin). 2013 Mar-Apr;7(2):85-96. doi: 10.4161/chan.23258. Epub 2013 Jan 17.


KCNE genetics and pharmacogenomics in cardiac arrhythmias: much ado about nothing?

Abbott GW.

Expert Rev Clin Pharmacol. 2013 Jan;6(1):49-60. doi: 10.1586/ecp.12.76. Review.

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