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Items: 13

1.

LRRK2 and ubiquitination: implications for kinase inhibitor therapy.

Melrose HL.

Biochem J. 2015 Sep 15;470(3):e21-4. doi: 10.1042/BJ20150785.

2.

Progressive dopaminergic alterations and mitochondrial abnormalities in LRRK2 G2019S knock-in mice.

Yue M, Hinkle KM, Davies P, Trushina E, Fiesel FC, Christenson TA, Schroeder AS, Zhang L, Bowles E, Behrouz B, Lincoln SJ, Beevers JE, Milnerwood AJ, Kurti A, McLean PJ, Fryer JD, Springer W, Dickson DW, Farrer MJ, Melrose HL.

Neurobiol Dis. 2015 Jun;78:172-95. doi: 10.1016/j.nbd.2015.02.031. Epub 2015 Mar 31.

3.

LRRK2, a puzzling protein: insights into Parkinson's disease pathogenesis.

Esteves AR, Swerdlow RH, Cardoso SM.

Exp Neurol. 2014 Nov;261:206-16. doi: 10.1016/j.expneurol.2014.05.025. Epub 2014 Jun 4. Review.

4.

Role of LRRK2 kinase dysfunction in Parkinson disease.

Kumar A, Cookson MR.

Expert Rev Mol Med. 2011 Jun 13;13:e20. doi: 10.1017/S146239941100192X. Review.

5.

Gender differences in the risk of familial parkinsonism: beyond LRRK2?

Saunders-Pullman R, Stanley K, San Luciano M, Barrett MJ, Shanker V, Raymond D, Ozelius LJ, Bressman SB.

Neurosci Lett. 2011 Jun 1;496(2):125-8. doi: 10.1016/j.neulet.2011.03.098. Epub 2011 Apr 12.

6.

Unravelling the role of defective genes.

Cookson MR.

Prog Brain Res. 2010;183:43-57. doi: 10.1016/S0079-6123(10)83003-1.

7.
8.

Genetic etiology of Parkinson disease associated with mutations in the SNCA, PARK2, PINK1, PARK7, and LRRK2 genes: a mutation update.

Nuytemans K, Theuns J, Cruts M, Van Broeckhoven C.

Hum Mutat. 2010 Jul;31(7):763-80. doi: 10.1002/humu.21277. Review.

9.

Parkinson's disease: Exit toxins, enter genetics.

Westerlund M, Hoffer B, Olson L.

Prog Neurobiol. 2010 Feb 9;90(2):146-56. doi: 10.1016/j.pneurobio.2009.11.001. Epub 2009 Nov 17. Review.

10.

Leucine-rich repeat kinase 2 mutations and Parkinson's disease: three questions.

Greggio E, Cookson MR.

ASN Neuro. 2009 Apr 14;1(1). pii: e00002. doi: 10.1042/AN20090007. Review.

11.

Progression of dopaminergic dysfunction in a LRRK2 kindred: a multitracer PET study.

Nandhagopal R, Mak E, Schulzer M, McKenzie J, McCormick S, Sossi V, Ruth TJ, Strongosky A, Farrer MJ, Wszolek ZK, Stoessl AJ.

Neurology. 2008 Nov 25;71(22):1790-5. doi: 10.1212/01.wnl.0000335973.66333.58.

12.

Genetic neuropathology of Parkinson's disease.

Cookson MR, Hardy J, Lewis PA.

Int J Clin Exp Pathol. 2008 Jan 1;1(3):217-31.

13.

The LRRK2 gene in Parkinson's disease: mutation screening in patients from Germany.

Schlitter AM, Woitalla D, Mueller T, Epplen JT, Dekomien G.

J Neurol Neurosurg Psychiatry. 2006 Jul;77(7):891-2. No abstract available.

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