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Items: 1 to 20 of 222

1.

Targeting Cell Survival Proteins for Cancer Cell Death.

Pandey MK, Prasad S, Tyagi AK, Deb L, Huang J, Karelia DN, Amin SG, Aggarwal BB.

Pharmaceuticals (Basel). 2016 Feb 25;9(1). pii: E11. doi: 10.3390/ph9010011. Review.

2.

Deubiquitylating enzyme USP9x regulates radiosensitivity in glioblastoma cells by Mcl-1-dependent and -independent mechanisms.

Wolfsperger F, Hogh-Binder SA, Schittenhelm J, Psaras T, Ritter V, Bornes L, Huber SM, Jendrossek V, Rudner J.

Cell Death Dis. 2016 Jan 14;7:e2039. doi: 10.1038/cddis.2015.405.

3.

Human Cytomegalovirus Stimulates the Synthesis of Select Akt-Dependent Antiapoptotic Proteins during Viral Entry To Promote Survival of Infected Monocytes.

Peppenelli MA, Arend KC, Cojohari O, Moorman NJ, Chan GC.

J Virol. 2016 Jan 6;90(6):3138-47. doi: 10.1128/JVI.02879-15.

PMID:
26739047
4.

Bay 61-3606 Sensitizes TRAIL-Induced Apoptosis by Downregulating Mcl-1 in Breast Cancer Cells.

Kim SY, Park SE, Shim SM, Park S, Kim KK, Jeong SY, Choi EK, Hwang JJ, Jin DH, Chung CD, Kim I.

PLoS One. 2015 Dec 31;10(12):e0146073. doi: 10.1371/journal.pone.0146073. eCollection 2015.

5.

Oxidative stress-dependent phosphorylation activates ZNRF1 to induce neuronal/axonal degeneration.

Wakatsuki S, Furuno A, Ohshima M, Araki T.

J Cell Biol. 2015 Nov 23;211(4):881-96. doi: 10.1083/jcb.201506102. Epub 2015 Nov 16.

PMID:
26572622
6.

Mitochondrial E3 ubiquitin ligase MARCH5 controls mitochondrial fission and cell sensitivity to stress-induced apoptosis through regulation of MiD49 protein.

Xu S, Cherok E, Das S, Li S, Roelofs BA, Ge SX, Polster BM, Boyman L, Lederer WJ, Wang C, Karbowski M.

Mol Biol Cell. 2016 Jan 15;27(2):349-59. doi: 10.1091/mbc.E15-09-0678. Epub 2015 Nov 12.

7.

Regulation of Bim in Health and Disease.

Sionov RV, Vlahopoulos SA, Granot Z.

Oncotarget. 2015 Sep 15;6(27):23058-134. Review.

8.

A specific E3 ligase/deubiquitinase pair modulates TBP protein levels during muscle differentiation.

Li L, Martinez SS, Hu W, Liu Z, Tjian R.

Elife. 2015 Sep 22;4:e08536. doi: 10.7554/eLife.08536.

9.

Mcl-1 downregulation leads to the heightened sensitivity exhibited by BCR-ABL positive ALL to induction of energy and ER-stress.

Leclerc GJ, DeSalvo J, Du J, Gao N, Leclerc GM, Lehrman MA, Lampidis TJ, Barredo JC.

Leuk Res. 2015 Aug 20. pii: S0145-2126(15)30360-X. doi: 10.1016/j.leukres.2015.08.007. [Epub ahead of print]

PMID:
26346348
10.

Staurosporine resistance in inflammatory neutrophils is associated with the inhibition of caspase- and proteasome-mediated Mcl-1 degradation.

Hornstein T, Lehmann S, Philipp D, Detmer S, Hoffmann M, Peter C, Wesselborg S, Unfried K, Windolf J, Flohé S, Paunel-Görgülü A.

J Leukoc Biol. 2016 Jan;99(1):163-74. doi: 10.1189/jlb.3A1114-537RR. Epub 2015 Aug 26.

PMID:
26310832
11.

Attacking cancer's Achilles heel: antagonism of anti-apoptotic BCL-2 family members.

Opferman JT.

FEBS J. 2015 Aug 21. doi: 10.1111/febs.13472. [Epub ahead of print] Review.

PMID:
26293580
12.

Regulation of c-Myc expression by the histone demethylase JMJD1A is essential for prostate cancer cell growth and survival.

Fan L, Peng G, Sahgal N, Fazli L, Gleave M, Zhang Y, Hussain A, Qi J.

Oncogene. 2015 Aug 17. doi: 10.1038/onc.2015.309. [Epub ahead of print]

PMID:
26279298
13.

Inhibition of polo like kinase 1 in sarcomas induces apoptosis that is dependent on Mcl-1 suppression.

Nair JS, Schwartz GK.

Cell Cycle. 2015;14(19):3101-11. doi: 10.1080/15384101.2015.1078033.

PMID:
26236920
14.

Syk-mediated tyrosine phosphorylation of mule promotes TNF-induced JNK activation and cell death.

Lee CK, Yang Y, Chen C, Liu J.

Oncogene. 2016 Apr 14;35(15):1988-95. doi: 10.1038/onc.2015.275. Epub 2015 Jul 27.

PMID:
26212014
15.

Structure-Function Analysis of the Mcl-1 Protein Identifies a Novel Senescence-regulating Domain.

Demelash A, Pfannenstiel LW, Tannenbaum CS, Li X, Kalady MF, DeVecchio J, Gastman BR.

J Biol Chem. 2015 Sep 4;290(36):21962-75. doi: 10.1074/jbc.M115.663898. Epub 2015 Jul 23.

PMID:
26205817
16.

Combined inhibition of Bcl-2/Bcl-xL and Usp9X/Bag3 overcomes apoptotic resistance in glioblastoma in vitro and in vivo.

Karpel-Massler G, Shu C, Chau L, Banu M, Halatsch ME, Westhoff MA, Ramirez Y, Ross AH, Bruce JN, Canoll P, Siegelin MD.

Oncotarget. 2015 Jun 10;6(16):14507-21.

17.

How mitochondrial dynamism orchestrates mitophagy.

Shirihai OS, Song M, Dorn GW 2nd.

Circ Res. 2015 May 22;116(11):1835-49. doi: 10.1161/CIRCRESAHA.116.306374. Review.

PMID:
25999423
18.

DNA damage-induced activation of CUL4B targets HUWE1 for proteasomal degradation.

Yi J, Lu G, Li L, Wang X, Cao L, Lin M, Zhang S, Shao G.

Nucleic Acids Res. 2015 May 19;43(9):4579-90. doi: 10.1093/nar/gkv325. Epub 2015 Apr 16.

19.
20.

Regulation of the DNA damage response by ubiquitin conjugation.

Brinkmann K, Schell M, Hoppe T, Kashkar H.

Front Genet. 2015 Mar 10;6:98. doi: 10.3389/fgene.2015.00098. eCollection 2015. Review.

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