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Items: 16


Estrogen Effects on Cognitive and Synaptic Health Over the Lifecourse.

Hara Y, Waters EM, McEwen BS, Morrison JH.

Physiol Rev. 2015 Jul;95(3):785-807. doi: 10.1152/physrev.00036.2014. Review.


Estrogen: a master regulator of bioenergetic systems in the brain and body.

Rettberg JR, Yao J, Brinton RD.

Front Neuroendocrinol. 2014 Jan;35(1):8-30. doi: 10.1016/j.yfrne.2013.08.001. Epub 2013 Aug 29. Review.


Estrogen regulation of mitochondrial bioenergetics: implications for prevention of Alzheimer's disease.

Yao J, Brinton RD.

Adv Pharmacol. 2012;64:327-71. doi: 10.1016/B978-0-12-394816-8.00010-6. Review.


A reversible early oxidized redox state that precedes macromolecular ROS damage in aging nontransgenic and 3xTg-AD mouse neurons.

Ghosh D, LeVault KR, Barnett AJ, Brewer GJ.

J Neurosci. 2012 Apr 25;32(17):5821-32. doi: 10.1523/JNEUROSCI.6192-11.2012.


Role of estrogen receptor alpha and beta expression and signaling on cognitive function during aging.

Foster TC.

Hippocampus. 2012 Apr;22(4):656-69. doi: 10.1002/hipo.20935. Epub 2011 Apr 27. Review.


Epigenetic oxidative redox shift (EORS) theory of aging unifies the free radical and insulin signaling theories.

Brewer GJ.

Exp Gerontol. 2010 Mar;45(3):173-9. doi: 10.1016/j.exger.2009.11.007. Epub 2009 Nov 27. Review.


Age-related deficiencies in complex I endogenous substrate availability and reserve capacity of complex IV in cortical neuron electron transport.

Jones TT, Brewer GJ.

Biochim Biophys Acta. 2010 Feb;1797(2):167-76. doi: 10.1016/j.bbabio.2009.09.009. Epub 2009 Sep 30.


Aging alters the expression of genes for neuroprotection and synaptic function following acute estradiol treatment.

Aenlle KK, Foster TC.

Hippocampus. 2010 Sep;20(9):1047-60. doi: 10.1002/hipo.20703.


Estradiol reverses a calcium-related biomarker of brain aging in female rats.

Brewer LD, Dowling AL, Curran-Rauhut MA, Landfield PW, Porter NM, Blalock EM.

J Neurosci. 2009 May 13;29(19):6058-67. doi: 10.1523/JNEUROSCI.5253-08.2009.


Neuron network activity scales exponentially with synapse density.

Brewer GJ, Boehler MD, Pearson RA, DeMaris AA, Ide AN, Wheeler BC.

J Neural Eng. 2009 Feb;6(1):014001. doi: 10.1088/1741-2560/6/1/014001. Epub 2008 Dec 22.


Critical age-related loss of cofactors of neuron cytochrome C oxidase reversed by estrogen.

Jones TT, Brewer GJ.

Exp Neurol. 2009 Feb;215(2):212-9. doi: 10.1016/j.expneurol.2008.09.011. Epub 2008 Sep 30.


Age-related changes to tumor necrosis factor receptors affect neuron survival in the presence of beta-amyloid.

Patel JR, Brewer GJ.

J Neurosci Res. 2008 Aug 1;86(10):2303-13. doi: 10.1002/jnr.21663.


NbActiv4 medium improvement to Neurobasal/B27 increases neuron synapse densities and network spike rates on multielectrode arrays.

Brewer GJ, Boehler MD, Jones TT, Wheeler BC.

J Neurosci Methods. 2008 May 30;170(2):181-7. doi: 10.1016/j.jneumeth.2008.01.009. Epub 2008 Jan 20.

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