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Results: 1 to 20 of 61

1.

HspB1, HspB5 and HspB4 in Human Cancers: Potent Oncogenic Role of Some of Their Client Proteins.

Arrigo AP, Gibert B.

Cancers (Basel). 2014 Feb 7;6(1):333-65. doi: 10.3390/cancers6010333.

PMID:
24514166
[PubMed]
Free PMC Article
2.

Human serum albumin and p53-activating peptide fusion protein is able to promote apoptosis and deliver fatty acid-modified molecules.

Joshi MR, Yao N, Myers KA, Li Z.

PLoS One. 2013 Nov 21;8(11):e80926. doi: 10.1371/journal.pone.0080926. eCollection 2013.

PMID:
24278348
[PubMed - in process]
Free PMC Article
3.

USP7 inhibitor P22077 inhibits neuroblastoma growth via inducing p53-mediated apoptosis.

Fan YH, Cheng J, Vasudevan SA, Dou J, Zhang H, Patel RH, Ma IT, Rojas Y, Zhao Y, Yu Y, Zhang H, Shohet JM, Nuchtern JG, Kim ES, Yang J.

Cell Death Dis. 2013 Oct 17;4:e867. doi: 10.1038/cddis.2013.400.

PMID:
24136231
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

5-Deazaflavin derivatives as inhibitors of p53 ubiquitination by HDM2.

Dickens MP, Roxburgh P, Hock A, Mezna M, Kellam B, Vousden KH, Fischer PM.

Bioorg Med Chem. 2013 Nov 15;21(22):6868-77. doi: 10.1016/j.bmc.2013.09.038. Epub 2013 Sep 25.

PMID:
24113239
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

The MDM2-p53 pathway revisited.

Nag S, Qin J, Srivenugopal KS, Wang M, Zhang R.

J Biomed Res. 2013 Jul;27(4):254-71. doi: 10.7555/JBR.27.20130030. Epub 2013 Jun 6.

PMID:
23885265
[PubMed]
Free PMC Article
6.

A novel mechanism of crosstalk between the p53 and NFκB pathways: MDM2 binds and inhibits p65RelA.

Heyne K, Winter C, Gerten F, Schmidt C, Roemer K.

Cell Cycle. 2013 Aug 1;12(15):2479-92. doi: 10.4161/cc.25495. Epub 2013 Jun 28.

PMID:
23839035
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Targeting the ubiquitin-proteasome system for cancer therapy.

Shen M, Schmitt S, Buac D, Dou QP.

Expert Opin Ther Targets. 2013 Sep;17(9):1091-108. doi: 10.1517/14728222.2013.815728. Epub 2013 Jul 4. Review.

PMID:
23822887
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Inauhzin sensitizes p53-dependent cytotoxicity and tumor suppression of chemotherapeutic agents.

Zhang Y, Zhang Q, Zeng SX, Hao Q, Lu H.

Neoplasia. 2013 May;15(5):523-34.

PMID:
23633924
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

MDM2, MDMX and p53 in oncogenesis and cancer therapy.

Wade M, Li YC, Wahl GM.

Nat Rev Cancer. 2013 Feb;13(2):83-96. doi: 10.1038/nrc3430. Epub 2013 Jan 10. Review.

PMID:
23303139
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Molecular pathways: targeting Mdm2 and Mdm4 in cancer therapy.

Li Q, Lozano G.

Clin Cancer Res. 2013 Jan 1;19(1):34-41. doi: 10.1158/1078-0432.CCR-12-0053. Epub 2012 Dec 21. Review.

PMID:
23262034
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Targeting the ubiquitin-mediated proteasome degradation of p53 for cancer therapy.

Devine T, Dai MS.

Curr Pharm Des. 2013;19(18):3248-62. Review.

PMID:
23151129
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

The Ubiquitin Proteasome Pathway (UPP) in the regulation of cell cycle control and DNA damage repair and its implication in tumorigenesis.

Tu Y, Chen C, Pan J, Xu J, Zhou ZG, Wang CY.

Int J Clin Exp Pathol. 2012;5(8):726-38. Epub 2012 Oct 1. Review.

PMID:
23071855
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Inauhzin and Nutlin3 synergistically activate p53 and suppress tumor growth.

Zhang Y, Zhang Q, Zeng SX, Zhang Y, Mayo LD, Lu H.

Cancer Biol Ther. 2012 Aug;13(10):915-24. doi: 10.4161/cbt.20844. Epub 2012 Aug 1.

PMID:
22785205
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Ubiquitylation in immune disorders and cancer: from molecular mechanisms to therapeutic implications.

Fulda S, Rajalingam K, Dikic I.

EMBO Mol Med. 2012 Jul;4(7):545-56. doi: 10.1002/emmm.201100707. Epub 2012 Jun 25. Review.

PMID:
22730341
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Hepatic stem cells and transforming growth factor β in hepatocellular carcinoma.

Majumdar A, Curley SA, Wu X, Brown P, Hwang JP, Shetty K, Yao ZX, He AR, Li S, Katz L, Farci P, Mishra L.

Nat Rev Gastroenterol Hepatol. 2012 Sep;9(9):530-8. doi: 10.1038/nrgastro.2012.114. Epub 2012 Jun 19. Review.

PMID:
22710573
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

The Fbw7 and betaTRCP E3 ubiquitin ligases and their roles in tumorigenesis.

Lau AW, Fukushima H, Wei W.

Front Biosci (Landmark Ed). 2012 Jun 1;17:2197-212. Review.

PMID:
22652772
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

PepSite: prediction of peptide-binding sites from protein surfaces.

Trabuco LG, Lise S, Petsalaki E, Russell RB.

Nucleic Acids Res. 2012 Jul;40(Web Server issue):W423-7. doi: 10.1093/nar/gks398. Epub 2012 May 16.

PMID:
22600738
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Discovery of Mdm2-MdmX E3 ligase inhibitors using a cell-based ubiquitination assay.

Herman AG, Hayano M, Poyurovsky MV, Shimada K, Skouta R, Prives C, Stockwell BR.

Cancer Discov. 2011 Sep;1(4):312-25. doi: 10.1158/2159-8290.CD-11-0104. Epub 2011 Jul 28.

PMID:
22586610
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Regulation of p53: a collaboration between Mdm2 and Mdmx.

Pei D, Zhang Y, Zheng J.

Oncotarget. 2012 Mar;3(3):228-35. Review.

PMID:
22410433
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Functional analysis and consequences of Mdm2 E3 ligase inhibition in human tumor cells.

Wade M, Li YC, Matani AS, Braun SM, Milanesi F, Rodewald LW, Wahl GM.

Oncogene. 2012 Nov 8;31(45):4789-97. doi: 10.1038/onc.2011.625. Epub 2012 Jan 23.

PMID:
22266850
[PubMed - indexed for MEDLINE]
Free PMC Article

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