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Items: 1 to 20 of 22


Tumor-specific targeting by Bavituximab, a phosphatidylserine-targeting monoclonal antibody with vascular targeting and immune modulating properties, in lung cancer xenografts.

Gerber DE, Hao G, Watkins L, Stafford JH, Anderson J, Holbein B, Öz OK, Mathews D, Thorpe PE, Hassan G, Kumar A, Brekken RA, Sun X.

Am J Nucl Med Mol Imaging. 2015 Oct 12;5(5):493-503. eCollection 2015.


Phosphatidylserine (PS) Is Exposed in Choroidal Neovascular Endothelium: PS-Targeting Antibodies Inhibit Choroidal Angiogenesis In Vivo and Ex Vivo.

Li T, Aredo B, Zhang K, Zhong X, Pulido JS, Wang S, He YG, Huang X, Brekken RA, Ufret-Vincenty RL.

Invest Ophthalmol Vis Sci. 2015 Nov 1;56(12):7137-45. doi: 10.1167/iovs.15-17302.


A phase I clinical trial of bavituximab and paclitaxel in patients with HER2 negative metastatic breast cancer.

Chalasani P, Marron M, Roe D, Clarke K, Iannone M, Livingston RB, Shan JS, Stopeck AT.

Cancer Med. 2015 Jul;4(7):1051-9. doi: 10.1002/cam4.447. Epub 2015 Mar 31.


Effective binding of a phosphatidylserine-targeting antibody to Ebola virus infected cells and purified virions.

Dowall SD, Graham VA, Corbin-Lickfett K, Empig C, Schlunegger K, Bruce CB, Easterbrook L, Hewson R.

J Immunol Res. 2015;2015:347903. doi: 10.1155/2015/347903. Epub 2015 Mar 1.


Highly specific PET imaging of prostate tumors in mice with an iodine-124-labeled antibody fragment that targets phosphatidylserine.

Stafford JH, Hao G, Best AM, Sun X, Thorpe PE.

PLoS One. 2013 Dec 19;8(12):e84864. doi: 10.1371/journal.pone.0084864. eCollection 2013.


A combination of radiosurgery and soluble tissue factor enhances vascular targeting for experimental glioblastoma.

Tu J, Hu Z, Chen Z.

Biomed Res Int. 2013;2013:390714. doi: 10.1155/2013/390714. Epub 2013 Nov 6.


Systemic delivery of SapC-DOPS has antiangiogenic and antitumor effects against glioblastoma.

Wojton J, Chu Z, Mathsyaraja H, Meisen WH, Denton N, Kwon CH, Chow LM, Palascak M, Franco R, Bourdeau T, Thornton S, Ostrowski MC, Kaur B, Qi X.

Mol Ther. 2013 Aug;21(8):1517-25. doi: 10.1038/mt.2013.114. Epub 2013 Jun 4.


Measuring response to therapy by near-infrared imaging of tumors using a phosphatidylserine-targeting antibody fragment.

Gong J, Archer R, Brown M, Fisher S, Chang C, Peacock M, Hughes C, Freimark B.

Mol Imaging. 2013 Jun;12(4):244-56.


Biomarkers and molecular probes for cell death imaging and targeted therapeutics.

Smith BA, Smith BD.

Bioconjug Chem. 2012 Oct 17;23(10):1989-2006. doi: 10.1021/bc3003309. Epub 2012 Sep 26. Review.


Vascular endothelial-targeted therapy combined with cytotoxic chemotherapy induces inflammatory intratumoral infiltrates and inhibits tumor relapses after surgery.

Judy BF, Aliperti LA, Predina JD, Levine D, Kapoor V, Thorpe PE, Albelda SM, Singhal S.

Neoplasia. 2012 Apr;14(4):352-9.


High resolution tumor targeting in living mice by means of multispectral optoacoustic tomography.

Buehler A, Herzog E, Ale A, Smith BD, Ntziachristos V, Razansky D.

EJNMMI Res. 2012 Apr 1;2:14. doi: 10.1186/2191-219X-2-14.


Near-infrared Optical Imaging of Exposed Phosphatidylserine in a Mouse Glioma Model.

Zhao D, Stafford JH, Zhou H, Thorpe PE.

Transl Oncol. 2011 Dec;4(6):355-64. Epub 2011 Dec 1.


Retargeting adenoviral vectors to improve gene transfer into tumors.

Hogg RT, Thorpe P, Gerard RD.

Cancer Gene Ther. 2011 Apr;18(4):275-87. doi: 10.1038/cgt.2010.78. Epub 2010 Dec 24.


Clearance of apoptotic cells: implications in health and disease.

Elliott MR, Ravichandran KS.

J Cell Biol. 2010 Jun 28;189(7):1059-70. doi: 10.1083/jcb.201004096. Review.


Phosphatidylserine targeting for diagnosis and treatment of human diseases.

Schutters K, Reutelingsperger C.

Apoptosis. 2010 Sep;15(9):1072-82. doi: 10.1007/s10495-010-0503-y. Review.


Targeting mutant p53 protein and the tumor vasculature: an effective combination therapy for advanced breast tumors.

Liang Y, Besch-Williford C, Benakanakere I, Thorpe PE, Hyder SM.

Breast Cancer Res Treat. 2011 Jan;125(2):407-20. doi: 10.1007/s10549-010-0851-x. Epub 2010 Mar 27.


Optical imaging of mammary and prostate tumors in living animals using a synthetic near infrared zinc(II)-dipicolylamine probe for anionic cell surfaces.

Smith BA, Akers WJ, Leevy WM, Lampkins AJ, Xiao S, Wolter W, Suckow MA, Achilefu S, Smith BD.

J Am Chem Soc. 2010 Jan 13;132(1):67-9. doi: 10.1021/ja908467y.


Endothelial expression of autocrine VEGF upon the uptake of tumor-derived microvesicles containing oncogenic EGFR.

Al-Nedawi K, Meehan B, Kerbel RS, Allison AC, Rak J.

Proc Natl Acad Sci U S A. 2009 Mar 10;106(10):3794-9. doi: 10.1073/pnas.0804543106. Epub 2009 Feb 20.


CNS delivery via adsorptive transcytosis.

Hervé F, Ghinea N, Scherrmann JM.

AAPS J. 2008 Sep;10(3):455-72. doi: 10.1208/s12248-008-9055-2. Epub 2008 Aug 26. Review.

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