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Items: 12

1.

Analysis of the Zidovudine Resistance Mutations T215Y, M41L, and L210W in HIV-1 Reverse Transcriptase.

Boyer PL, Das K, Arnold E, Hughes SH.

Antimicrob Agents Chemother. 2015 Dec;59(12):7184-96. doi: 10.1128/AAC.05069-14. Epub 2015 Aug 31.

2.

Formation of a quaternary complex of HIV-1 reverse transcriptase with a nucleotide-competing inhibitor and its ATP enhancer.

Ehteshami M, Nijhuis M, Bernatchez JA, Ablenas CJ, McCormick S, de Jong D, Jochmans D, Götte M.

J Biol Chem. 2013 Jun 14;288(24):17336-46. doi: 10.1074/jbc.M112.433441. Epub 2013 Apr 18.

3.

NTP-mediated nucleotide excision activity of hepatitis C virus RNA-dependent RNA polymerase.

Jin Z, Leveque V, Ma H, Johnson KA, Klumpp K.

Proc Natl Acad Sci U S A. 2013 Jan 29;110(5):E348-57. doi: 10.1073/pnas.1214924110. Epub 2013 Jan 10.

4.

HIV-1 and HIV-2 reverse transcriptases: different mechanisms of resistance to nucleoside reverse transcriptase inhibitors.

Boyer PL, Clark PK, Hughes SH.

J Virol. 2012 May;86(10):5885-94. doi: 10.1128/JVI.06597-11. Epub 2012 Mar 21.

5.

HIV-1 polymerase inhibition by nucleoside analogs: cellular- and kinetic parameters of efficacy, susceptibility and resistance selection.

von Kleist M, Metzner P, Marquet R, Schütte C.

PLoS Comput Biol. 2012 Jan;8(1):e1002359. doi: 10.1371/journal.pcbi.1002359. Epub 2012 Jan 19.

6.

The "Connection" Between HIV Drug Resistance and RNase H.

Delviks-Frankenberry KA, Nikolenko GN, Pathak VK.

Viruses. 2010 Jul 1;2(7):1476-1503.

7.

The Role of Nucleotide Excision by Reverse Transcriptase in HIV Drug Resistance.

Acosta-Hoyos AJ, Scott WA.

Viruses. 2010 Jan 28;2(2):372-394.

8.

Utilization of a deoxynucleoside diphosphate substrate by HIV reverse transcriptase.

Garforth SJ, Parniak MA, Prasad VR.

PLoS One. 2008 Apr 30;3(4):e2074. doi: 10.1371/journal.pone.0002074.

9.

AZT resistance of simian foamy virus reverse transcriptase is based on the excision of AZTMP in the presence of ATP.

Hartl MJ, Kretzschmar B, Frohn A, Nowrouzi A, Rethwilm A, Wöhrl BM.

Nucleic Acids Res. 2008 Feb;36(3):1009-16. Epub 2007 Dec 20.

10.

Pyrophosphorolytic excision of nonobligate chain terminators by hepatitis C virus NS5B polymerase.

Deval J, Powdrill MH, D'Abramo CM, Cellai L, Götte M.

Antimicrob Agents Chemother. 2007 Aug;51(8):2920-8. Epub 2007 May 14.

12.

Mg2+ dependency of HIV-1 reverse transcription, inhibition by nucleoside analogues and resistance.

Goldschmidt V, Didierjean J, Ehresmann B, Ehresmann C, Isel C, Marquet R.

Nucleic Acids Res. 2006 Jan 3;34(1):42-52. Print 2006.

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