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Results: 13

1.

UV light activates a Gαq/11-coupled phototransduction pathway in human melanocytes.

Bellono NW, Najera JA, Oancea E.

J Gen Physiol. 2014 Feb;143(2):203-14. doi: 10.1085/jgp.201311094.

PMID:
24470488
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Molecular chaperoning function of Ric-8 is to fold nascent heterotrimeric G protein α subunits.

Chan P, Thomas CJ, Sprang SR, Tall GG.

Proc Natl Acad Sci U S A. 2013 Mar 5;110(10):3794-9. doi: 10.1073/pnas.1220943110. Epub 2013 Feb 19.

PMID:
23431197
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Ric-8 proteins are molecular chaperones that direct nascent G protein α subunit membrane association.

Gabay M, Pinter ME, Wright FA, Chan P, Murphy AJ, Valenzuela DM, Yancopoulos GD, Tall GG.

Sci Signal. 2011 Nov 22;4(200):ra79. doi: 10.1126/scisignal.2002223.

PMID:
22114146
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

The Ric-8B gene is highly expressed in proliferating preosteoblastic cells and downregulated during osteoblast differentiation in a SWI/SNF- and C/EBPbeta-mediated manner.

Grandy R, Sepulveda H, Aguilar R, Pihan P, Henriquez B, Olate J, Montecino M.

Mol Cell Biol. 2011 Jul;31(14):2997-3008. doi: 10.1128/MCB.05096-11. Epub 2011 May 23.

PMID:
21606199
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Phospholipase C epsilon scaffolds to muscle-specific A kinase anchoring protein (mAKAPbeta) and integrates multiple hypertrophic stimuli in cardiac myocytes.

Zhang L, Malik S, Kelley GG, Kapiloff MS, Smrcka AV.

J Biol Chem. 2011 Jul 1;286(26):23012-21. doi: 10.1074/jbc.M111.231993. Epub 2011 May 5.

PMID:
21550986
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Purification of heterotrimeric G protein alpha subunits by GST-Ric-8 association: primary characterization of purified G alpha(olf).

Chan P, Gabay M, Wright FA, Kan W, Oner SS, Lanier SM, Smrcka AV, Blumer JB, Tall GG.

J Biol Chem. 2011 Jan 28;286(4):2625-35. doi: 10.1074/jbc.M110.178897. Epub 2010 Nov 29.

PMID:
21115479
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

A structural determinant that renders G alpha(i) sensitive to activation by GIV/girdin is required to promote cell migration.

Garcia-Marcos M, Ghosh P, Ear J, Farquhar MG.

J Biol Chem. 2010 Apr 23;285(17):12765-77. doi: 10.1074/jbc.M109.045161. Epub 2010 Feb 15.

PMID:
20157114
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Biophysical studies support a predicted superhelical structure with armadillo repeats for Ric-8.

Figueroa M, Hinrichs MV, Bunster M, Babbitt P, Martinez-Oyanedel J, Olate J.

Protein Sci. 2009 Jun;18(6):1139-45. doi: 10.1002/pro.124.

PMID:
19472323
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

GIV is a nonreceptor GEF for G alpha i with a unique motif that regulates Akt signaling.

Garcia-Marcos M, Ghosh P, Farquhar MG.

Proc Natl Acad Sci U S A. 2009 Mar 3;106(9):3178-83. doi: 10.1073/pnas.0900294106. Epub 2009 Feb 11.

PMID:
19211784
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

G protein betagamma subunits as targets for small molecule therapeutic development.

Smrcka AV, Lehmann DM, Dessal AL.

Comb Chem High Throughput Screen. 2008 Jun;11(5):382-95. Review.

PMID:
18537559
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

State-selective binding peptides for heterotrimeric G-protein subunits: novel tools for investigating G-protein signaling dynamics.

Johnston CA, Willard FS, Ramer JK, Blaesius R, Roques CN, Siderovski DP.

Comb Chem High Throughput Screen. 2008 Jun;11(5):370-81. Review.

PMID:
18537558
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

G protein βγ subunits: central mediators of G protein-coupled receptor signaling.

Smrcka AV.

Cell Mol Life Sci. 2008 Jul;65(14):2191-214. doi: 10.1007/s00018-008-8006-5. Review.

PMID:
18488142
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Coactivation of G protein signaling by cell-surface receptors and an intracellular exchange factor.

Lee MJ, Dohlman HG.

Curr Biol. 2008 Feb 12;18(3):211-5. doi: 10.1016/j.cub.2008.01.007.

PMID:
18261907
[PubMed - indexed for MEDLINE]
Free PMC Article

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