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Items: 1 to 20 of 28

1.

Notum deacylates Wnt proteins to suppress signalling activity.

Kakugawa S, Langton PF, Zebisch M, Howell SA, Chang TH, Liu Y, Feizi T, Bineva G, O'Reilly N, Snijders AP, Jones EY, Vincent JP.

Nature. 2015 Mar 12;519(7542):187-92. doi: 10.1038/nature14259. Epub 2015 Feb 25.

2.

Coexpression of SFRP1 and WIF1 as a prognostic predictor of favorable outcomes in patients with colorectal carcinoma.

Huang S, Zhong X, Gao J, Song R, Wu H, Zi S, Yang S, Du P, Cui L, Yang C, Li Z.

Biomed Res Int. 2014;2014:256723. doi: 10.1155/2014/256723. Epub 2014 May 14.

3.

Hox targets and cellular functions.

Sánchez-Herrero E.

Scientifica (Cairo). 2013;2013:738257. doi: 10.1155/2013/738257. Epub 2013 Dec 30. Erratum in: Scientifica (Cairo). 2014;2014:529298.

4.

The hedgehog pathway gene shifted functions together with the hmgcr-dependent isoprenoid biosynthetic pathway to orchestrate germ cell migration.

Deshpande G, Zhou K, Wan JY, Friedrich J, Jourjine N, Smith D, Schedl P.

PLoS Genet. 2013;9(9):e1003720. doi: 10.1371/journal.pgen.1003720. Epub 2013 Sep 12.

5.

A fully human inhibitory monoclonal antibody to the Wnt receptor RYK.

Halford MM, Macheda ML, Parish CL, Takano EA, Fox S, Layton D, Nice E, Stacker SA.

PLoS One. 2013 Sep 18;8(9):e75447. doi: 10.1371/journal.pone.0075447. eCollection 2013.

6.

Morphogen gradients in development: from form to function.

Christian JL.

Wiley Interdiscip Rev Dev Biol. 2012 Jan-Feb;1(1):3-15. doi: 10.1002/wdev.2. Epub 2011 Nov 17.

7.

Absolute requirement of cholesterol binding for Hedgehog gradient formation in Drosophila.

Ducuing A, Mollereau B, Axelrod JD, Vincent S.

Biol Open. 2013 May 9;2(6):596-604. doi: 10.1242/bio.20134952. Print 2013 Jun 15.

8.

The Drosophila WIF1 homolog Shifted maintains glypican-independent Hedgehog signaling and interacts with the Hedgehog co-receptors Ihog and Boi.

Avanesov A, Blair SS.

Development. 2013 Jan 1;140(1):107-16. doi: 10.1242/dev.078444. Epub 2012 Nov 15.

9.

Wnt inhibitory factor 1 (Wif1) is regulated by androgens and enhances androgen-dependent prostate development.

Keil KP, Mehta V, Branam AM, Abler LL, Buresh-Stiemke RA, Joshi PS, Schmitz CT, Marker PC, Vezina CM.

Endocrinology. 2012 Dec;153(12):6091-103. doi: 10.1210/en.2012-1564. Epub 2012 Oct 18.

10.

The role of glypicans in Wnt inhibitory factor-1 activity and the structural basis of Wif1's effects on Wnt and Hedgehog signaling.

Avanesov A, Honeyager SM, Malicki J, Blair SS.

PLoS Genet. 2012;8(2):e1002503. doi: 10.1371/journal.pgen.1002503. Epub 2012 Feb 23.

11.

DSulfatase-1 fine-tunes Hedgehog patterning activity through a novel regulatory feedback loop.

Wojcinski A, Nakato H, Soula C, Glise B.

Dev Biol. 2011 Oct 1;358(1):168-80. doi: 10.1016/j.ydbio.2011.07.027. Epub 2011 Jul 23.

12.

Extracellular movement of signaling molecules.

Müller P, Schier AF.

Dev Cell. 2011 Jul 19;21(1):145-58. doi: 10.1016/j.devcel.2011.06.001. Review.

13.

Modular mechanism of Wnt signaling inhibition by Wnt inhibitory factor 1.

Malinauskas T, Aricescu AR, Lu W, Siebold C, Jones EY.

Nat Struct Mol Biol. 2011 Jul 10;18(8):886-93. doi: 10.1038/nsmb.2081.

14.

Overlapping roles and collective requirement for the coreceptors GAS1, CDO, and BOC in SHH pathway function.

Allen BL, Song JY, Izzi L, Althaus IW, Kang JS, Charron F, Krauss RS, McMahon AP.

Dev Cell. 2011 Jun 14;20(6):775-87. doi: 10.1016/j.devcel.2011.04.018.

15.

Wnt-inhibitory factor 1 dysregulation of the bone marrow niche exhausts hematopoietic stem cells.

Schaniel C, Sirabella D, Qiu J, Niu X, Lemischka IR, Moore KA.

Blood. 2011 Sep 1;118(9):2420-9. doi: 10.1182/blood-2010-09-305664. Epub 2011 Jun 7.

16.

Interactions between Hedgehog proteins and their binding partners come into view.

Beachy PA, Hymowitz SG, Lazarus RA, Leahy DJ, Siebold C.

Genes Dev. 2010 Sep 15;24(18):2001-12. doi: 10.1101/gad.1951710. Review.

17.

Shaping morphogen gradients by proteoglycans.

Yan D, Lin X.

Cold Spring Harb Perspect Biol. 2009 Sep;1(3):a002493. doi: 10.1101/cshperspect.a002493. Review.

18.

Genetic and biochemical definition of the Hedgehog receptor.

Zheng X, Mann RK, Sever N, Beachy PA.

Genes Dev. 2010 Jan 1;24(1):57-71. doi: 10.1101/gad.1870310.

19.

Ggamma1, a downstream target for the hmgcr-isoprenoid biosynthetic pathway, is required for releasing the Hedgehog ligand and directing germ cell migration.

Deshpande G, Godishala A, Schedl P.

PLoS Genet. 2009 Jan;5(1):e1000333. doi: 10.1371/journal.pgen.1000333. Epub 2009 Jan 9.

20.

The adventures of sonic hedgehog in development and repair. III. Hedgehog processing and biological activity.

Farzan SF, Singh S, Schilling NS, Robbins DJ.

Am J Physiol Gastrointest Liver Physiol. 2008 Apr;294(4):G844-9. doi: 10.1152/ajpgi.00564.2007. Epub 2008 Jan 31. Review.

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