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Results: 1 to 20 of 68

1.

Inhibition of eIF2α dephosphorylation enhances TRAIL-induced apoptosis in hepatoma cells.

Teng Y, Gao M, Wang J, Kong Q, Hua H, Luo T, Jiang Y.

Cell Death Dis. 2014 Feb 13;5:e1060. doi: 10.1038/cddis.2014.24.

PMID:
24525736
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

6-Shogaol induces apoptosis in human leukemia cells through a process involving caspase-mediated cleavage of eIF2α.

Liu Q, Peng YB, Zhou P, Qi LW, Zhang M, Gao N, Liu EH, Li P.

Mol Cancer. 2013 Nov 12;12(1):135. doi: 10.1186/1476-4598-12-135.

PMID:
24215632
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

NEAT1 long noncoding RNA regulates transcription via protein sequestration within subnuclear bodies.

Hirose T, Virnicchi G, Tanigawa A, Naganuma T, Li R, Kimura H, Yokoi T, Nakagawa S, Bénard M, Fox AH, Pierron G.

Mol Biol Cell. 2014 Jan;25(1):169-83. doi: 10.1091/mbc.E13-09-0558. Epub 2013 Oct 30.

PMID:
24173718
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Protein synthesis rate is the predominant regulator of protein expression during differentiation.

Kristensen AR, Gsponer J, Foster LJ.

Mol Syst Biol. 2013;9:689. doi: 10.1038/msb.2013.47.

PMID:
24045637
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

CHOP induces activating transcription factor 5 (ATF5) to trigger apoptosis in response to perturbations in protein homeostasis.

Teske BF, Fusakio ME, Zhou D, Shan J, McClintick JN, Kilberg MS, Wek RC.

Mol Biol Cell. 2013 Aug;24(15):2477-90. doi: 10.1091/mbc.E13-01-0067. Epub 2013 Jun 12.

PMID:
23761072
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Activating transcription factor 4 and X box binding protein 1 of Litopenaeus vannamei transcriptional regulated white spot syndrome virus genes Wsv023 and Wsv083.

Li XY, Pang LR, Chen YG, Weng SP, Yue HT, Zhang ZZ, Chen YH, He JG.

PLoS One. 2013 Apr 24;8(4):e62603. doi: 10.1371/journal.pone.0062603. Print 2013.

PMID:
23638122
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Mammalian target of rapamycin complex 1 (mTORC1) enhances bortezomib-induced death in tuberous sclerosis complex (TSC)-null cells by a c-MYC-dependent induction of the unfolded protein response.

Babcock JT, Nguyen HB, He Y, Hendricks JW, Wek RC, Quilliam LA.

J Biol Chem. 2013 May 31;288(22):15687-98. doi: 10.1074/jbc.M112.431056. Epub 2013 Apr 23.

PMID:
23612979
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

IMPACT is a developmentally regulated protein in neurons that opposes the eukaryotic initiation factor 2α kinase GCN2 in the modulation of neurite outgrowth.

Roffé M, Hajj GN, Azevedo HF, Alves VS, Castilho BA.

J Biol Chem. 2013 Apr 12;288(15):10860-9. doi: 10.1074/jbc.M113.461970. Epub 2013 Feb 27.

PMID:
23447528
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Phosphorylation of eIF2α attenuates statin-induced apoptosis by inhibiting the stabilization and translocation of p53 to the mitochondria.

Lee SK, Kim YS.

Int J Oncol. 2013 Mar;42(3):810-6. doi: 10.3892/ijo.2013.1792. Epub 2013 Jan 23.

PMID:
23354132
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

hCG-induced endoplasmic reticulum stress triggers apoptosis and reduces steroidogenic enzyme expression through activating transcription factor 6 in Leydig cells of the testis.

Park SJ, Kim TS, Park CK, Lee SH, Kim JM, Lee KS, Lee IK, Park JW, Lawson MA, Lee DS.

J Mol Endocrinol. 2013 Feb 15;50(2):151-66. doi: 10.1530/JME-12-0195. Print 2013 Apr.

PMID:
23256993
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Global subcellular characterization of protein degradation using quantitative proteomics.

Larance M, Ahmad Y, Kirkwood KJ, Ly T, Lamond AI.

Mol Cell Proteomics. 2013 Mar;12(3):638-50. doi: 10.1074/mcp.M112.024547. Epub 2012 Dec 12.

PMID:
23242552
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Lovastatin induces multiple stress pathways including LKB1/AMPK activation that regulate its cytotoxic effects in squamous cell carcinoma cells.

Ma L, Niknejad N, Gorn-Hondermann I, Dayekh K, Dimitroulakos J.

PLoS One. 2012;7(9):e46055. doi: 10.1371/journal.pone.0046055. Epub 2012 Sep 28.

PMID:
23029387
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Failure of amino acid homeostasis causes cell death following proteasome inhibition.

Suraweera A, Münch C, Hanssum A, Bertolotti A.

Mol Cell. 2012 Oct 26;48(2):242-53. doi: 10.1016/j.molcel.2012.08.003. Epub 2012 Sep 6.

PMID:
22959274
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Identification of human proteins that modify misfolding and proteotoxicity of pathogenic ataxin-1.

Petrakis S, Raskó T, Russ J, Friedrich RP, Stroedicke M, Riechers SP, Muehlenberg K, Möller A, Reinhardt A, Vinayagam A, Schaefer MH, Boutros M, Tricoire H, Andrade-Navarro MA, Wanker EE.

PLoS Genet. 2012;8(8):e1002897. doi: 10.1371/journal.pgen.1002897. Epub 2012 Aug 16.

PMID:
22916034
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Phenotype selection reveals coevolution of muscle glycogen and protein and PTEN as a gate keeper for the accretion of muscle mass in adult female mice.

Sawitzky M, Zeissler A, Langhammer M, Bielohuby M, Stock P, Hammon HM, Görs S, Metges CC, Stoehr BJ, Bidlingmaier M, Fromm-Dornieden C, Baumgartner BG, Christ B, Brenig B, Binder G, Metzger F, Renne U, Hoeflich A.

PLoS One. 2012;7(6):e39711. doi: 10.1371/journal.pone.0039711. Epub 2012 Jun 29.

PMID:
22768110
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Eukaryotic initiation factor 2 phosphorylation and translational control in metabolism.

Baird TD, Wek RC.

Adv Nutr. 2012 May 1;3(3):307-21. doi: 10.3945/an.112.002113. Review.

PMID:
22585904
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Islet β-cell endoplasmic reticulum stress precedes the onset of type 1 diabetes in the nonobese diabetic mouse model.

Tersey SA, Nishiki Y, Templin AT, Cabrera SM, Stull ND, Colvin SC, Evans-Molina C, Rickus JL, Maier B, Mirmira RG.

Diabetes. 2012 Apr;61(4):818-27. doi: 10.2337/db11-1293.

PMID:
22442300
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Nucleofection induces transient eIF2α phosphorylation by GCN2 and PERK.

Anderson BR, Karikó K, Weissman D.

Gene Ther. 2013 Feb;20(2):136-42. doi: 10.1038/gt.2012.5. Epub 2012 Feb 2.

PMID:
22301437
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Increased susceptibility to DNA virus infection in mice with a GCN2 mutation.

Won S, Eidenschenk C, Arnold CN, Siggs OM, Sun L, Brandl K, Mullen TM, Nemerow GR, Moresco EM, Beutler B.

J Virol. 2012 Feb;86(3):1802-8. doi: 10.1128/JVI.05660-11. Epub 2011 Nov 23.

PMID:
22114338
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Protein aggregation of SERCA2 mutants associated with Darier disease elicits ER stress and apoptosis in keratinocytes.

Wang Y, Bruce AT, Tu C, Ma K, Zeng L, Zheng P, Liu Y, Liu Y.

J Cell Sci. 2011 Nov 1;124(Pt 21):3568-80. doi: 10.1242/jcs.084053. Epub 2011 Nov 1.

PMID:
22045735
[PubMed - indexed for MEDLINE]
Free PMC Article

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