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Items: 1 to 20 of 37

1.

Non-Classical Inhibition of Carbonic Anhydrase.

Lomelino CL, Supuran CT, McKenna R.

Int J Mol Sci. 2016 Jul 16;17(7). pii: E1150. doi: 10.3390/ijms17071150. Review.

2.

Tracking solvent and protein movement during CO2 release in carbonic anhydrase II crystals.

Kim CU, Song H, Avvaru BS, Gruner SM, Park S, McKenna R.

Proc Natl Acad Sci U S A. 2016 May 10;113(19):5257-62. doi: 10.1073/pnas.1520786113. Epub 2016 Apr 25.

PMID:
27114542
3.

Joint neutron crystallographic and NMR solution studies of Tyr residue ionization and hydrogen bonding: Implications for enzyme-mediated proton transfer.

Michalczyk R, Unkefer CJ, Bacik JP, Schrader TE, Ostermann A, Kovalevsky AY, McKenna R, Fisher SZ.

Proc Natl Acad Sci U S A. 2015 May 5;112(18):5673-8. doi: 10.1073/pnas.1502255112. Epub 2015 Apr 20.

4.

Identifying Zn-bound histidine residues in metalloproteins using hydrogen-deuterium exchange mass spectrometry.

Dong J, Callahan KL, Borotto NB, Vachet RW.

Anal Chem. 2014 Jan 7;86(1):766-73. doi: 10.1021/ac4032719. Epub 2013 Dec 13.

5.

Peregrination of the selectivity filter delineates the pore of the human voltage-gated proton channel hHV1.

Morgan D, Musset B, Kulleperuma K, Smith SM, Rajan S, Cherny VV, Pomès R, DeCoursey TE.

J Gen Physiol. 2013 Dec;142(6):625-40. doi: 10.1085/jgp.201311045. Epub 2013 Nov 11.

6.

Voltage-gated proton channels: molecular biology, physiology, and pathophysiology of the H(V) family.

DeCoursey TE.

Physiol Rev. 2013 Apr;93(2):599-652. doi: 10.1152/physrev.00011.2012. Review.

7.

Malaria parasite carbonic anhydrase: inhibition of aromatic/heterocyclic sulfonamides and its therapeutic potential.

Krungkrai SR, Krungkrai J.

Asian Pac J Trop Biomed. 2011 Jun;1(3):233-42. doi: 10.1016/S2221-1691(11)60034-8. Review.

8.

Water networks in fast proton transfer during catalysis by human carbonic anhydrase II.

Mikulski R, West D, Sippel KH, Avvaru BS, Aggarwal M, Tu C, McKenna R, Silverman DN.

Biochemistry. 2013 Jan 8;52(1):125-31. doi: 10.1021/bi301099k. Epub 2012 Dec 18.

9.

Insights towards sulfonamide drug specificity in α-carbonic anhydrases.

Aggarwal M, Kondeti B, McKenna R.

Bioorg Med Chem. 2013 Mar 15;21(6):1526-33. doi: 10.1016/j.bmc.2012.08.019. Epub 2012 Aug 28.

10.

Kinetic and structural characterization of thermostabilized mutants of human carbonic anhydrase II.

Fisher Z, Boone CD, Biswas SM, Venkatakrishnan B, Aggarwal M, Tu C, Agbandje-McKenna M, Silverman D, McKenna R.

Protein Eng Des Sel. 2012 Jul;25(7):347-55. doi: 10.1093/protein/gzs027. Epub 2012 Jun 12.

11.

Transport activity of the sodium bicarbonate cotransporter NBCe1 is enhanced by different isoforms of carbonic anhydrase.

Schueler C, Becker HM, McKenna R, Deitmer JW.

PLoS One. 2011;6(11):e27167. doi: 10.1371/journal.pone.0027167. Epub 2011 Nov 4.

12.

Neutron structure of human carbonic anhydrase II: a hydrogen-bonded water network "switch" is observed between pH 7.8 and 10.0.

Fisher Z, Kovalevsky AY, Mustyakimov M, Silverman DN, McKenna R, Langan P.

Biochemistry. 2011 Nov 8;50(44):9421-3. doi: 10.1021/bi201487b. Epub 2011 Oct 12.

13.

Chemical rescue of enzymes: proton transfer in mutants of human carbonic anhydrase II.

Maupin CM, Castillo N, Taraphder S, Tu C, McKenna R, Silverman DN, Voth GA.

J Am Chem Soc. 2011 Apr 27;133(16):6223-34. doi: 10.1021/ja1097594. Epub 2011 Mar 31.

14.

Enzymes for carbon sequestration: neutron crystallographic studies of carbonic anhydrase.

Fisher SZ, Kovalevsky AY, Domsic J, Mustyakimov M, Silverman DN, McKenna R, Langan P.

Acta Crystallogr D Biol Crystallogr. 2010 Nov;66(Pt 11):1178-83. doi: 10.1107/S0907444910019700. Epub 2010 Oct 20.

15.

Comparison of solution and crystal properties of Co(II)-substituted human carbonic anhydrase II.

Avvaru BS, Arenas DJ, Tu C, Tanner DB, McKenna R, Silverman DN.

Arch Biochem Biophys. 2010 Oct 1;502(1):53-9. doi: 10.1016/j.abb.2010.07.010. Epub 2010 Jul 14.

16.

Structural and kinetic study of the extended active site for proton transfer in human carbonic anhydrase II.

Domsic JF, Williams W, Fisher SZ, Tu C, Agbandje-McKenna M, Silverman DN, McKenna R.

Biochemistry. 2010 Aug 3;49(30):6394-9. doi: 10.1021/bi1007645.

17.

Neutron structure of human carbonic anhydrase II: implications for proton transfer.

Fisher SZ, Kovalevsky AY, Domsic JF, Mustyakimov M, McKenna R, Silverman DN, Langan PA.

Biochemistry. 2010 Jan 26;49(3):415-21. doi: 10.1021/bi901995n.

18.

Characterization of CamH from Methanosarcina thermophila, founding member of a subclass of the {gamma} class of carbonic anhydrases.

Zimmerman SA, Tomb JF, Ferry JG.

J Bacteriol. 2010 Mar;192(5):1353-60. doi: 10.1128/JB.01164-09. Epub 2009 Dec 18.

19.

Proton transport in carbonic anhydrase: Insights from molecular simulation.

Maupin CM, Voth GA.

Biochim Biophys Acta. 2010 Feb;1804(2):332-41. doi: 10.1016/j.bbapap.2009.09.006. Epub 2009 Sep 16. Review.

20.

Proton transfer in catalysis and the role of proton shuttles in carbonic anhydrase.

Mikulski RL, Silverman DN.

Biochim Biophys Acta. 2010 Feb;1804(2):422-6. doi: 10.1016/j.bbapap.2009.08.003. Epub 2009 Aug 11.

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