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Items: 14


Replication-dependent and transcription-dependent mechanisms of DNA double-strand break induction by the topoisomerase 2-targeting drug etoposide.

Tammaro M, Barr P, Ricci B, Yan H.

PLoS One. 2013 Nov 7;8(11):e79202. doi: 10.1371/journal.pone.0079202. eCollection 2013.


Riccardin D Exerts Its Antitumor Activity by Inducing DNA Damage in PC-3 Prostate Cancer Cells In Vitro and In Vivo.

Hu Z, Kong F, Si M, Tian K, Yu LX, Young CY, Yuan H, Lou H.

PLoS One. 2013 Sep 17;8(9):e74387. doi: 10.1371/journal.pone.0074387. eCollection 2013.


Phenothiazine Inhibitors of TLKs Affect Double-Strand Break Repair and DNA Damage Response Recovery and Potentiate Tumor Killing with Radiomimetic Therapy.

Ronald S, Awate S, Rath A, Carroll J, Galiano F, Dwyer D, Kleiner-Hancock H, Mathis JM, Vigod S, De Benedetti A.

Genes Cancer. 2013 Jan;4(1-2):39-53. doi: 10.1177/1947601913479020.


The SNM1B/APOLLO DNA nuclease functions in resolution of replication stress and maintenance of common fragile site stability.

Mason JM, Das I, Arlt M, Patel N, Kraftson S, Glover TW, Sekiguchi JM.

Hum Mol Genet. 2013 Dec 15;22(24):4901-13. doi: 10.1093/hmg/ddt340. Epub 2013 Jul 17.


DNA2 and EXO1 in replication-coupled, homology-directed repair and in the interplay between HDR and the FA/BRCA network.

Karanja KK, Cox SW, Duxin JP, Stewart SA, Campbell JL.

Cell Cycle. 2012 Nov 1;11(21):3983-96. doi: 10.4161/cc.22215. Epub 2012 Sep 17.


More forks on the road to replication stress recovery.

Allen C, Ashley AK, Hromas R, Nickoloff JA.

J Mol Cell Biol. 2011 Feb;3(1):4-12. doi: 10.1093/jmcb/mjq049. Review.


Protein phosphatase 2A-dependent dephosphorylation of replication protein A is required for the repair of DNA breaks induced by replication stress.

Feng J, Wakeman T, Yong S, Wu X, Kornbluth S, Wang XF.

Mol Cell Biol. 2009 Nov;29(21):5696-709. doi: 10.1128/MCB.00191-09. Epub 2009 Aug 24.


Physical interaction between replication protein A (RPA) and MRN: involvement of RPA2 phosphorylation and the N-terminus of RPA1.

Oakley GG, Tillison K, Opiyo SA, Glanzer JG, Horn JM, Patrick SM.

Biochemistry. 2009 Aug 11;48(31):7473-81. doi: 10.1021/bi900694p.


Acetaldehyde stimulates FANCD2 monoubiquitination, H2AX phosphorylation, and BRCA1 phosphorylation in human cells in vitro: implications for alcohol-related carcinogenesis.

Marietta C, Thompson LH, Lamerdin JE, Brooks PJ.

Mutat Res. 2009 May 12;664(1-2):77-83. doi: 10.1016/j.mrfmmm.2009.03.011. Epub 2009 Apr 5.


MRE11 complex links RECQ5 helicase to sites of DNA damage.

Zheng L, Kanagaraj R, Mihaljevic B, Schwendener S, Sartori AA, Gerrits B, Shevelev I, Janscak P.

Nucleic Acids Res. 2009 May;37(8):2645-57. doi: 10.1093/nar/gkp147. Epub 2009 Mar 6.


DNA damage and homologous recombination signaling induced by thymidylate deprivation.

Yang Z, Waldman AS, Wyatt MD.

Biochem Pharmacol. 2008 Oct 15;76(8):987-96. doi: 10.1016/j.bcp.2008.08.010. Epub 2008 Aug 19.


Enhanced phosphorylation of Nbs1, a member of DNA repair/checkpoint complex Mre11-RAD50-Nbs1, can be targeted to increase the efficacy of imatinib mesylate against BCR/ABL-positive leukemia cells.

Rink L, Slupianek A, Stoklosa T, Nieborowska-Skorska M, Urbanska K, Seferynska I, Reiss K, Skorski T.

Blood. 2007 Jul 15;110(2):651-60. Epub 2007 Apr 12.


Functions of human replication protein A (RPA): from DNA replication to DNA damage and stress responses.

Zou Y, Liu Y, Wu X, Shell SM.

J Cell Physiol. 2006 Aug;208(2):267-73. Review.

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