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Items: 1 to 20 of 26


Well-mixed plasma and tissue viral populations in RT-SHIV-infected macaques implies a lack of viral replication in the tissues during antiretroviral therapy.

Kearney MF, Anderson EM, Coomer C, Smith L, Shao W, Johnson N, Kline C, Spindler J, Mellors JW, Coffin JM, Ambrose Z.

Retrovirology. 2015 Nov 11;12:93. doi: 10.1186/s12977-015-0212-2.


Low Frequency of Drug-Resistant Variants Selected by Long-Acting Rilpivirine in Macaques Infected with Simian Immunodeficiency Virus Containing HIV-1 Reverse Transcriptase.

Melody K, McBeth S, Kline C, Kashuba AD, Mellors JW, Ambrose Z.

Antimicrob Agents Chemother. 2015 Dec;59(12):7762-70. doi: 10.1128/AAC.01937-15. Epub 2015 Oct 5.


Differential regulatory activities of viral protein X for anti-viral efficacy of nucleos(t)ide reverse transcriptase inhibitors in monocyte-derived macrophages and activated CD4(+) T cells.

Hollenbaugh JA, Schader SM, Schinazi RF, Kim B.

Virology. 2015 Nov;485:313-21. doi: 10.1016/j.virol.2015.08.006. Epub 2015 Aug 29.


Prophylactic and therapeutic effect of AZT/3TC in RT-SHIV infected Chinese-origin rhesus macaques.

Wang W, Yao N, Cong Z, Jiang H, Qin C, Wei Q.

AIDS Res Ther. 2014 Mar 4;11(1):12. doi: 10.1186/1742-6405-11-12.


Residual viremia in an RT-SHIV rhesus macaque HAART model marked by the presence of a predominant plasma clone and a lack of viral evolution.

Kauffman RC, Villalobos A, Bowen JH, Adamson L, Schinazi RF.

PLoS One. 2014 Feb 5;9(2):e88258. doi: 10.1371/journal.pone.0088258. eCollection 2014.


Analysis of multiply spliced transcripts in lymphoid tissue reservoirs of rhesus macaques infected with RT-SHIV during HAART.

Deere JD, Kauffman RC, Cannavo E, Higgins J, Villalobos A, Adamson L, Schinazi RF, Luciw PA, North TW.

PLoS One. 2014 Feb 5;9(2):e87914. doi: 10.1371/journal.pone.0087914. eCollection 2014.


Variation of human immunodeficiency virus type-1 reverse transcriptase within the simian immunodeficiency virus genome of RT-SHIV.

Wadford DA, Kauffman RC, Deere JD, Aoki ST, Stanton RA, Higgins J, Van Rompay KK, Villalobos A, Nettles JH, Schinazi RF, Pedersen NC, North TW.

PLoS One. 2014 Jan 31;9(1):e86997. doi: 10.1371/journal.pone.0086997. eCollection 2014.


Persistence of viral reservoirs in multiple tissues after antiretroviral therapy suppression in a macaque RT-SHIV model.

Kline C, Ndjomou J, Franks T, Kiser R, Coalter V, Smedley J, Piatak M Jr, Mellors JW, Lifson JD, Ambrose Z.

PLoS One. 2013 Dec 18;8(12):e84275. doi: 10.1371/journal.pone.0084275. eCollection 2013.


Macaque-tropic human immunodeficiency virus type 1: breaking out of the host restriction factors.

Saito A, Akari H.

Front Microbiol. 2013 Jul 9;4:187. doi: 10.3389/fmicb.2013.00187. eCollection 2013.


Breaking Barriers to an AIDS Model with Macaque-Tropic HIV-1 Derivatives.

Thippeshappa R, Ruan H, Kimata JT.

Biology (Basel). 2012 May 12;1(2):134-64. doi: 10.3390/biology1020134.


Animal models for HIV/AIDS research.

Hatziioannou T, Evans DT.

Nat Rev Microbiol. 2012 Dec;10(12):852-67. doi: 10.1038/nrmicro2911. Review.


Animal models for microbicide studies.

Veazey RS, Shattock RJ, Klasse PJ, Moore JP.

Curr HIV Res. 2012 Jan 1;10(1):79-87. Review.


Genetic diversity of simian immunodeficiency virus encoding HIV-1 reverse transcriptase persists in macaques despite antiretroviral therapy.

Kearney M, Spindler J, Shao W, Maldarelli F, Palmer S, Hu SL, Lifson JD, KewalRamani VN, Mellors JW, Coffin JM, Ambrose Z.

J Virol. 2011 Jan;85(2):1067-76. doi: 10.1128/JVI.01701-10. Epub 2010 Nov 17.


Viral sanctuaries during highly active antiretroviral therapy in a nonhuman primate model for AIDS.

North TW, Higgins J, Deere JD, Hayes TL, Villalobos A, Adamson L, Shacklett BL, Schinazi RF, Luciw PA.

J Virol. 2010 Mar;84(6):2913-22. doi: 10.1128/JVI.02356-09. Epub 2009 Dec 23.


RT-SHIV, an infectious CCR5-tropic chimeric virus suitable for evaluating HIV reverse transcriptase inhibitors in macaque models.

Jiang Y, Tian B, Saifuddin M, Agy MB, Emau P, Cairns JS, Tsai CC.

AIDS Res Ther. 2009 Nov 5;6:23. doi: 10.1186/1742-6405-6-23.


RT-SHIV subpopulation dynamics in infected macaques during anti-HIV therapy.

Shao W, Kearney M, Maldarelli F, Mellors JW, Stephens RM, Lifson JD, KewalRamani VN, Ambrose Z, Coffin JM, Palmer SE.

Retrovirology. 2009 Nov 4;6:101. doi: 10.1186/1742-4690-6-101.


Simian immunodeficiency virus SIVrcm, a unique CCR2-tropic virus, selectively depletes memory CD4+ T cells in pigtailed macaques through expanded coreceptor usage in vivo.

Gautam R, Gaufin T, Butler I, Gautam A, Barnes M, Mandell D, Pattison M, Tatum C, Macfarland J, Monjure C, Marx PA, Pandrea I, Apetrei C.

J Virol. 2009 Aug;83(16):7894-908. doi: 10.1128/JVI.00444-09. Epub 2009 Jun 3.


Selection of a simian-human immunodeficiency virus strain resistant to a vaginal microbicide in macaques.

Dudley DM, Wentzel JL, Lalonde MS, Veazey RS, Arts EJ.

J Virol. 2009 May;83(10):5067-76. doi: 10.1128/JVI.00055-09. Epub 2009 Mar 11.

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