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Cited In for PubMed (Select 15563275)


The hypoxia-inducible miR-429 regulates hypoxia-inducible factor-1α expression in human endothelial cells through a negative feedback loop.

Bartoszewska S, Kochan K, Piotrowski A, Kamysz W, Ochocka RJ, Collawn JF, Bartoszewski R.

FASEB J. 2015 Apr;29(4):1467-79. doi: 10.1096/fj.14-267054. Epub 2014 Dec 30.


The hypoxia-inducible factor pathway, prolyl hydroxylase domain protein inhibitors, and their roles in bone repair and regeneration.

Fan L, Li J, Yu Z, Dang X, Wang K.

Biomed Res Int. 2014;2014:239356. doi: 10.1155/2014/239356. Epub 2014 May 11. Review.


HIF-1 α had pivotal effects on downregulation of miR-210 decreasing viability and inducing apoptosis in hypoxic chondrocytes.

Chang Z, Huo L, Wu Y, Zhang P.

ScientificWorldJournal. 2014 Mar 25;2014:876363. doi: 10.1155/2014/876363. eCollection 2014.


Prolyl-hydroxylase 3: Evolving Roles for an Ancient Signaling Protein.

Place TL, Domann FE.

Hypoxia (Auckl). 2013 Oct 1;2013(1):13-17.


Tight control of hypoxia-inducible factor-α transient dynamics is essential for cell survival in hypoxia.

Bagnall J, Leedale J, Taylor SE, Spiller DG, White MR, Sharkey KJ, Bearon RN, Sée V.

J Biol Chem. 2014 Feb 28;289(9):5549-64. doi: 10.1074/jbc.M113.500405. Epub 2014 Jan 6.


Function and expression of prolyl hydroxylase 3 in cancers.

Liu QL, Liang QL, Li ZY, Zhou Y, Ou WT, Huang ZG.

Arch Med Sci. 2013 Aug 30;9(4):589-93. doi: 10.5114/aoms.2013.36987. Epub 2013 Aug 29.


Hypoxia-inducible factor (HIF) network: insights from mathematical models.

Cavadas MA, Nguyen LK, Cheong A.

Cell Commun Signal. 2013 Jun 10;11(1):42. doi: 10.1186/1478-811X-11-42.


Redox signaling pathways involved in neuronal ischemic preconditioning.

Thompson JW, Narayanan SV, Perez-Pinzon MA.

Curr Neuropharmacol. 2012 Dec;10(4):354-69. doi: 10.2174/157015912804143577.


MiR199b Suppresses Expression of Hypoxia-Inducible Factor 1α (HIF-1α) in Prostate Cancer Cells.

Shang W, Chen X, Nie L, Xu M, Chen N, Zeng H, Zhou Q.

Int J Mol Sci. 2013 Apr 17;14(4):8422-36. doi: 10.3390/ijms14048422.


Prolyl hydroxylase 3 (PHD3) modulates catabolic effects of tumor necrosis factor-α (TNF-α) on cells of the nucleus pulposus through co-activation of nuclear factor κB (NF-κB)/p65 signaling.

Fujita N, Gogate SS, Chiba K, Toyama Y, Shapiro IM, Risbud MV.

J Biol Chem. 2012 Nov 16;287(47):39942-53. doi: 10.1074/jbc.M112.375964. Epub 2012 Sep 4.


Identification and functional characterization of pVHL-dependent cell surface proteins in renal cell carcinoma.

Boysen G, Bausch-Fluck D, Thoma CR, Nowicka AM, Stiehl DP, Cima I, Luu VD, von Teichman A, Hermanns T, Sulser T, Ingold-Heppner B, Fankhauser N, Wenger RH, Krek W, Schraml P, Wollscheid B, Moch H.

Neoplasia. 2012 Jun;14(6):535-46.


Expression of prolyl hydroxylases (PHDs) is selectively controlled by HIF-1 and HIF-2 proteins in nucleus pulposus cells of the intervertebral disc: distinct roles of PHD2 and PHD3 proteins in controlling HIF-1α activity in hypoxia.

Fujita N, Markova D, Anderson DG, Chiba K, Toyama Y, Shapiro IM, Risbud MV.

J Biol Chem. 2012 May 11;287(20):16975-86. doi: 10.1074/jbc.M111.334466. Epub 2012 Mar 26.


Discovery of a new molecular probe ML228: an activator of the hypoxia inducible factor (HIF) pathway.

Theriault JR, Felts AS, Bates BS, Perez JR, Palmer M, Gilbert SR, Dawson ES, Engers JL, Lindsley CW, Emmitte KA.

Bioorg Med Chem Lett. 2012 Jan 1;22(1):76-81. doi: 10.1016/j.bmcl.2011.11.077. Epub 2011 Nov 28.


Synthetic transactivation screening reveals ETV4 as broad coactivator of hypoxia-inducible factor signaling.

Wollenick K, Hu J, Kristiansen G, Schraml P, Rehrauer H, Berchner-Pfannschmidt U, Fandrey J, Wenger RH, Stiehl DP.

Nucleic Acids Res. 2012 Mar;40(5):1928-43. doi: 10.1093/nar/gkr978. Epub 2011 Nov 10.


HIF-1α and HIF-2α degradation is differentially regulated in nucleus pulposus cells of the intervertebral disc.

Fujita N, Chiba K, Shapiro IM, Risbud MV.

J Bone Miner Res. 2012 Feb;27(2):401-12. doi: 10.1002/jbmr.538.


The chromatin remodeler ISWI regulates the cellular response to hypoxia: role of FIH.

Melvin A, Mudie S, Rocha S.

Mol Biol Cell. 2011 Nov;22(21):4171-81. doi: 10.1091/mbc.E11-02-0163. Epub 2011 Sep 7.


Human AlkB homologue 5 is a nuclear 2-oxoglutarate dependent oxygenase and a direct target of hypoxia-inducible factor 1α (HIF-1α).

Thalhammer A, Bencokova Z, Poole R, Loenarz C, Adam J, O'Flaherty L, Schödel J, Mole D, Giaslakiotis K, Schofield CJ, Hammond EM, Ratcliffe PJ, Pollard PJ.

PLoS One. 2011 Jan 14;6(1):e16210. doi: 10.1371/journal.pone.0016210.


Adenomatous polyposis coli and hypoxia-inducible factor-1{alpha} have an antagonistic connection.

Newton IP, Kenneth NS, Appleton PL, Näthke I, Rocha S.

Mol Biol Cell. 2010 Nov 1;21(21):3630-8. doi: 10.1091/mbc.E10-04-0312. Epub 2010 Sep 15.


Prolyl hydroxylase domain (PHD) 2 affects cell migration and F-actin formation via RhoA/rho-associated kinase-dependent cofilin phosphorylation.

Vogel S, Wottawa M, Farhat K, Zieseniss A, Schnelle M, Le-Huu S, von Ahlen M, Malz C, Camenisch G, Katschinski DM.

J Biol Chem. 2010 Oct 29;285(44):33756-63. doi: 10.1074/jbc.M110.132985. Epub 2010 Aug 27.


Endothelin-1 inhibits prolyl hydroxylase domain 2 to activate hypoxia-inducible factor-1alpha in melanoma cells.

Spinella F, Rosanò L, Del Duca M, Di Castro V, Nicotra MR, Natali PG, Bagnato A.

PLoS One. 2010 Jun 21;5(6):e11241. doi: 10.1371/journal.pone.0011241.

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