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Items: 1 to 20 of 97


The somatotropic axis and aging: Benefits of endocrine defects.

Bartke A, List EO, Kopchick JJ.

Growth Horm IGF Res. 2016 Apr;27:41-5. doi: 10.1016/j.ghir.2016.02.002. Epub 2016 Feb 16. Review.


Growth hormone modulates hypothalamic inflammation in long-lived pituitary dwarf mice.

Sadagurski M, Landeryou T, Cady G, Kopchick JJ, List EO, Berryman DE, Bartke A, Miller RA.

Aging Cell. 2015 Dec;14(6):1045-54. doi: 10.1111/acel.12382. Epub 2015 Aug 12.


IGF-1 Regulates Vertebral Bone Aging Through Sex-Specific and Time-Dependent Mechanisms.

Ashpole NM, Herron JC, Mitschelen MC, Farley JA, Logan S, Yan H, Ungvari Z, Hodges EL, Csiszar A, Ikeno Y, Humphrey MB, Sonntag WE.

J Bone Miner Res. 2016 Feb;31(2):443-54. doi: 10.1002/jbmr.2689. Epub 2015 Sep 3.


Circulating microRNA signature of genotype-by-age interactions in the long-lived Ames dwarf mouse.

Victoria B, Dhahbi JM, Nunez Lopez YO, Spinel L, Atamna H, Spindler SR, Masternak MM.

Aging Cell. 2015 Dec;14(6):1055-66. doi: 10.1111/acel.12373. Epub 2015 Jul 14.


Longevity and skeletal muscle mass: the role of IGF signalling, the sirtuins, dietary restriction and protein intake.

Sharples AP, Hughes DC, Deane CS, Saini A, Selman C, Stewart CE.

Aging Cell. 2015 Aug;14(4):511-23. doi: 10.1111/acel.12342. Epub 2015 Apr 10. Review.


Modelling the p53/p66Shc Aging Pathway in the Shortest Living Vertebrate Nothobranchius Furzeri.

Priami C, De Michele G, Cotelli F, Cellerino A, Giorgio M, Pelicci PG, Migliaccio E.

Aging Dis. 2015 Mar 10;6(2):95-108. doi: 10.14336/AD.2014.0228. eCollection 2015 Mar. Review.


Diminished mTOR signaling: a common mode of action for endocrine longevity factors.

Lamming DW.

Springerplus. 2014 Dec 15;3:735. doi: 10.1186/2193-1801-3-735. eCollection 2014. Review.


Regulation of mTOR activity in Snell dwarf and GH receptor gene-disrupted mice.

Dominick G, Berryman DE, List EO, Kopchick JJ, Li X, Miller RA, Garcia GG.

Endocrinology. 2015 Feb;156(2):565-75. doi: 10.1210/en.2014-1690. Epub 2014 Dec 2.


The effect of calorie restriction on insulin signaling in skeletal muscle and adipose tissue of Ames dwarf mice.

Wiesenborn DS, Menon V, Zhi X, Do A, Gesing A, Wang Z, Bartke A, Altomare DA, Masternak MM.

Aging (Albany NY). 2014 Oct;6(10):900-12.


Pharmacologic Means of Extending Lifespan.

Lamming DW, Sabatini DM, Baur JA.

J Clin Exp Pathol. 2012 May 17;Suppl 4. pii: 7327. No abstract available.


Mitochondrial chaperone TRAP1 activates the mitochondrial UPR and extends healthspan in Drosophila.

Baqri RM, Pietron AV, Gokhale RH, Turner BA, Kaguni LS, Shingleton AW, Kunes S, Miller KE.

Mech Ageing Dev. 2014 Nov-Dec;141-142:35-45. doi: 10.1016/j.mad.2014.09.002. Epub 2014 Sep 26.


Specific suppression of insulin sensitivity in growth hormone receptor gene-disrupted (GHR-KO) mice attenuates phenotypic features of slow aging.

Arum O, Boparai RK, Saleh JK, Wang F, Dirks AL, Turner JG, Kopchick JJ, Liu JL, Khardori RK, Bartke A.

Aging Cell. 2014 Dec;13(6):981-1000. doi: 10.1111/acel.12262. Epub 2014 Sep 20.


Growth hormone signaling is necessary for lifespan extension by dietary methionine.

Brown-Borg HM, Rakoczy SG, Wonderlich JA, Rojanathammanee L, Kopchick JJ, Armstrong V, Raasakka D.

Aging Cell. 2014 Dec;13(6):1019-27. doi: 10.1111/acel.12269. Epub 2014 Sep 19.


Insulin sensitivity in long-living Ames dwarf mice.

Wiesenborn DS, Ayala JE, King E, Masternak MM.

Age (Dordr). 2014;36(5):9709. doi: 10.1007/s11357-014-9709-1. Epub 2014 Aug 29.


Growth hormone abolishes beneficial effects of calorie restriction in long-lived Ames dwarf mice.

Gesing A, Al-Regaiey KA, Bartke A, Masternak MM.

Exp Gerontol. 2014 Oct;58:219-29. doi: 10.1016/j.exger.2014.08.010. Epub 2014 Aug 21.


IGF-I regulates the age-dependent signaling peptide humanin.

Lee C, Wan J, Miyazaki B, Fang Y, Guevara-Aguirre J, Yen K, Longo V, Bartke A, Cohen P.

Aging Cell. 2014 Oct;13(5):958-61. doi: 10.1111/acel.12243. Epub 2014 Jul 18.


Effects of insulin-like growth factor 1 on glutathione S-transferases and thioredoxin in growth hormone receptor knockout mice.

Rojanathammanee L, Rakoczy S, Kopchick J, Brown-Borg HM.

Age (Dordr). 2014;36(4):9687. doi: 10.1007/s11357-014-9687-3. Epub 2014 Jul 8.


Preservation of blood glucose homeostasis in slow-senescing somatotrophism-deficient mice subjected to intermittent fasting begun at middle or old age.

Arum O, Saleh JK, Boparai RK, Kopchick JJ, Khardori RK, Bartke A.

Age (Dordr). 2014 Jun;36(3):9651. doi: 10.1007/s11357-014-9651-2. Epub 2014 May 1. Erratum in: Age (Dordr). 2014 Aug;36(4):9695.


Long-lived crowded-litter mice exhibit lasting effects on insulin sensitivity and energy homeostasis.

Sadagurski M, Landeryou T, Blandino-Rosano M, Cady G, Elghazi L, Meister D, See L, Bartke A, Bernal-Mizrachi E, Miller RA.

Am J Physiol Endocrinol Metab. 2014 Jun 1;306(11):E1305-14. doi: 10.1152/ajpendo.00031.2014. Epub 2014 Apr 15.

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