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Commentary: MARCH8 Inhibits HIV-1 Infection by Reducing Virion Incorporation of Envelope Glycoproteins.

Fujita M.

Front Microbiol. 2016 Feb 24;7:254. doi: 10.3389/fmicb.2016.00254. eCollection 2016. No abstract available.


Derivation and Characterization of a CD4-Independent, Non-CD4-Tropic Simian Immunodeficiency Virus.

Swanstrom AE, Haggarty B, Jordan AP, Romano J, Leslie GJ, Aye PP, Marx PA, Lackner AA, Del Prete GQ, Robinson JE, Betts MR, Montefiori DC, LaBranche CC, Hoxie JA.

J Virol. 2016 Apr 29;90(10):4966-80. doi: 10.1128/JVI.02851-15. Print 2016 May 15.


Exclusive Decoration of Simian Immunodeficiency Virus Env with High-Mannose Type N-Glycans Is Not Compatible with Mucosal Transmission in Rhesus Macaques.

Karsten CB, Buettner FF, Cajic S, Nehlmeier I, Neumann B, Klippert A, Sauermann U, Reichl U, Gerardy-Schahn R, Rapp E, Stahl-Hennig C, Pöhlmann S.

J Virol. 2015 Nov;89(22):11727-33. doi: 10.1128/JVI.01358-15. Epub 2015 Sep 9.


Systematic analysis of intracellular trafficking motifs located within the cytoplasmic domain of simian immunodeficiency virus glycoprotein gp41.

Postler TS, Bixby JG, Desrosiers RC, Yuste E.

PLoS One. 2014 Dec 5;9(12):e114753. doi: 10.1371/journal.pone.0114753. eCollection 2014.


Identification and characterization of a macrophage-tropic SIV envelope glycoprotein variant in blood from early infection in SIVmac251-infected macaques.

Yen PJ, Mefford ME, Hoxie JA, Williams KC, Desrosiers RC, Gabuzda D.

Virology. 2014 Jun;458-459:53-68. doi: 10.1016/j.virol.2014.03.024. Epub 2014 May 8.


Loss of a conserved N-linked glycosylation site in the simian immunodeficiency virus envelope glycoprotein V2 region enhances macrophage tropism by increasing CD4-independent cell-to-cell transmission.

Yen PJ, Herschhorn A, Haim H, Salas I, Gu C, Sodroski J, Gabuzda D.

J Virol. 2014 May;88(9):5014-28. doi: 10.1128/JVI.02785-13. Epub 2014 Feb 19.


Variation of human immunodeficiency virus type-1 reverse transcriptase within the simian immunodeficiency virus genome of RT-SHIV.

Wadford DA, Kauffman RC, Deere JD, Aoki ST, Stanton RA, Higgins J, Van Rompay KK, Villalobos A, Nettles JH, Schinazi RF, Pedersen NC, North TW.

PLoS One. 2014 Jan 31;9(1):e86997. doi: 10.1371/journal.pone.0086997. eCollection 2014.


Increased infectivity in human cells and resistance to antibody-mediated neutralization by truncation of the SIV gp41 cytoplasmic tail.

Kuwata T, Kaori T, Enomoto I, Yoshimura K, Matsushita S.

Front Microbiol. 2013 May 14;4:117. doi: 10.3389/fmicb.2013.00117. eCollection 2013.


Conformational epitope consisting of the V3 and V4 loops as a target for potent and broad neutralization of simian immunodeficiency viruses.

Kuwata T, Takaki K, Yoshimura K, Enomoto I, Wu F, Ourmanov I, Hirsch VM, Yokoyama M, Sato H, Matsushita S.

J Virol. 2013 May;87(10):5424-36. doi: 10.1128/JVI.00201-13. Epub 2013 Mar 6.


Loss of a tyrosine-dependent trafficking motif in the simian immunodeficiency virus envelope cytoplasmic tail spares mucosal CD4 cells but does not prevent disease progression.

Breed MW, Jordan AP, Aye PP, Lichtveld CF, Midkiff CC, Schiro FR, Haggarty BS, Sugimoto C, Alvarez X, Sandler NG, Douek DC, Kuroda MJ, Pahar B, Piatak M Jr, Lifson JD, Keele BF, Hoxie JA, Lackner AA.

J Virol. 2013 Feb;87(3):1528-43. doi: 10.1128/JVI.01928-12. Epub 2012 Nov 14.


Neutralizing capacity of monoclonal antibodies that recognize peptide sequences underlying the carbohydrates on gp41 of simian immunodeficiency virus.

Martinez-Navio JM, Desrosiers RC.

J Virol. 2012 Dec;86(23):12484-93. doi: 10.1128/JVI.01959-12. Epub 2012 Sep 19.


Efficient transmission and persistence of low-frequency SIVmac251 variants in CD8-depleted rhesus macaques with different neuropathology.

Strickland SL, Gray RR, Lamers SL, Burdo TH, Huenink E, Nolan DJ, Nowlin B, Alvarez X, Midkiff CC, Goodenow MM, Williams K, Salemi M.

J Gen Virol. 2012 May;93(Pt 5):925-38. doi: 10.1099/vir.0.039586-0. Epub 2012 Feb 1.


Diversity of envelope genes from an uncloned stock of SIVmac251.

Bixby JG, Laur O, Johnson WE, Desrosiers RC.

AIDS Res Hum Retroviruses. 2010 Oct;26(10):1115-31. doi: 10.1089/aid.2010.0029. Epub 2010 Sep 13.


Generation of neutralizing antibodies and divergence of SIVmac239 in cynomolgus macaques following short-term early antiretroviral therapy.

Ozkaya Sahin G, Bowles EJ, Parker J, Uchtenhagen H, Sheik-Khalil E, Taylor S, Pybus OG, Mäkitalo B, Walther-Jallow L, Spångberg M, Thorstensson R, Achour A, Fenyö EM, Stewart-Jones GB, Spetz AL.

PLoS Pathog. 2010 Sep 2;6(9):e1001084. doi: 10.1371/journal.ppat.1001084.


Induction of antibody-mediated neutralization in SIVmac239 by a naturally acquired V3 mutation.

Faith SA, Wu Y, Kuhrt D, Steckbeck JD, Craigo JK, Clements JE, Cole KS.

Virology. 2010 Apr 25;400(1):86-92. doi: 10.1016/j.virol.2010.01.014. Epub 2010 Feb 11.


Intrathecal humoral responses are inversely associated with the frequency of simian immunodeficiency virus macrophage-tropic variants in the central nervous system.

Ryzhova E, Aye P, Harvey T, Cao W, Lackner A, González-Scarano F.

J Virol. 2009 Aug;83(16):8282-8. doi: 10.1128/JVI.00235-09. Epub 2009 Jun 3.


Vector-mediated gene transfer engenders long-lived neutralizing activity and protection against SIV infection in monkeys.

Johnson PR, Schnepp BC, Zhang J, Connell MJ, Greene SM, Yuste E, Desrosiers RC, Clark KR.

Nat Med. 2009 Aug;15(8):901-6. doi: 10.1038/nm.1967. Epub 2009 May 17.


Immunization with single-cycle SIV significantly reduces viral loads after an intravenous challenge with SIV(mac)239.

Jia B, Ng SK, DeGottardi MQ, Piatak M, Yuste E, Carville A, Mansfield KG, Li W, Richardson BA, Lifson JD, Evans DT.

PLoS Pathog. 2009 Jan;5(1):e1000272. doi: 10.1371/journal.ppat.1000272. Epub 2009 Jan 23.


The V1-V3 region of a brain-derived HIV-1 envelope glycoprotein determines macrophage tropism, low CD4 dependence, increased fusogenicity and altered sensitivity to entry inhibitors.

Rossi F, Querido B, Nimmagadda M, Cocklin S, Navas-Martín S, Martín-García J.

Retrovirology. 2008 Oct 6;5:89. doi: 10.1186/1742-4690-5-89.


Glycosylation of gp41 of simian immunodeficiency virus shields epitopes that can be targets for neutralizing antibodies.

Yuste E, Bixby J, Lifson J, Sato S, Johnson W, Desrosiers R.

J Virol. 2008 Dec;82(24):12472-86. doi: 10.1128/JVI.01382-08. Epub 2008 Oct 1.

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