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Items: 1 to 20 of 21

1.

Mechano-chemical kinetics of DNA replication: identification of the translocation step of a replicative DNA polymerase.

Morin JA, Cao FJ, Lázaro JM, Arias-Gonzalez JR, Valpuesta JM, Carrascosa JL, Salas M, Ibarra B.

Nucleic Acids Res. 2015 Apr 20;43(7):3643-52. doi: 10.1093/nar/gkv204. Epub 2015 Mar 23.

2.

Mechanism of RNA polymerase II bypass of oxidative cyclopurine DNA lesions.

Walmacq C, Wang L, Chong J, Scibelli K, Lubkowska L, Gnatt A, Brooks PJ, Wang D, Kashlev M.

Proc Natl Acad Sci U S A. 2015 Feb 3;112(5):E410-9. doi: 10.1073/pnas.1415186112. Epub 2015 Jan 20.

3.

Transcription factors IIS and IIF enhance transcription efficiency by differentially modifying RNA polymerase pausing dynamics.

Ishibashi T, Dangkulwanich M, Coello Y, Lionberger TA, Lubkowska L, Ponticelli AS, Kashlev M, Bustamante C.

Proc Natl Acad Sci U S A. 2014 Mar 4;111(9):3419-24. doi: 10.1073/pnas.1401611111. Epub 2014 Feb 18.

4.

Single-molecule studies of RNAPII elongation.

Zhou J, Schweikhard V, Block SM.

Biochim Biophys Acta. 2013 Jan;1829(1):29-38. doi: 10.1016/j.bbagrm.2012.08.006. Epub 2012 Sep 6. Review.

5.

Trigger loop dynamics mediate the balance between the transcriptional fidelity and speed of RNA polymerase II.

Larson MH, Zhou J, Kaplan CD, Palangat M, Kornberg RD, Landick R, Block SM.

Proc Natl Acad Sci U S A. 2012 Apr 24;109(17):6555-60. doi: 10.1073/pnas.1200939109. Epub 2012 Apr 9.

6.

Interaction of RNA polymerase II fork loop 2 with downstream non-template DNA regulates transcription elongation.

Kireeva ML, Domecq C, Coulombe B, Burton ZF, Kashlev M.

J Biol Chem. 2011 Sep 2;286(35):30898-910. doi: 10.1074/jbc.M111.260844. Epub 2011 Jul 5.

7.

The RPB2 flap loop of human RNA polymerase II is dispensable for transcription initiation and elongation.

Palangat M, Grass JA, Langelier MF, Coulombe B, Landick R.

Mol Cell Biol. 2011 Aug;31(16):3312-25. doi: 10.1128/MCB.05318-11. Epub 2011 Jun 13.

8.

Conformational coupling, bridge helix dynamics and active site dehydration in catalysis by RNA polymerase.

Seibold SA, Singh BN, Zhang C, Kireeva M, Domecq C, Bouchard A, Nazione AM, Feig M, Cukier RI, Coulombe B, Kashlev M, Hampsey M, Burton ZF.

Biochim Biophys Acta. 2010 Aug;1799(8):575-87. doi: 10.1016/j.bbagrm.2010.05.002. Epub 2010 May 15.

9.

Position of the general transcription factor TFIIF within the RNA polymerase II transcription preinitiation complex.

Eichner J, Chen HT, Warfield L, Hahn S.

EMBO J. 2010 Feb 17;29(4):706-16. doi: 10.1038/emboj.2009.386. Epub 2009 Dec 24.

10.

Forks, pincers, and triggers: the tools for nucleotide incorporation and translocation in multi-subunit RNA polymerases.

Erie DA, Kennedy SR.

Curr Opin Struct Biol. 2009 Dec;19(6):708-14. doi: 10.1016/j.sbi.2009.10.008. Epub 2009 Nov 11. Review.

12.

RNA polymerase active center: the molecular engine of transcription.

Nudler E.

Annu Rev Biochem. 2009;78:335-61. doi: 10.1146/annurev.biochem.76.052705.164655. Review.

13.

Rpb9 subunit controls transcription fidelity by delaying NTP sequestration in RNA polymerase II.

Walmacq C, Kireeva ML, Irvin J, Nedialkov Y, Lubkowska L, Malagon F, Strathern JN, Kashlev M.

J Biol Chem. 2009 Jul 17;284(29):19601-12. doi: 10.1074/jbc.M109.006908. Epub 2009 May 13.

14.

Millisecond phase kinetic analysis of elongation catalyzed by human, yeast, and Escherichia coli RNA polymerase.

Kireeva M, Nedialkov YA, Gong XQ, Zhang C, Xiong Y, Moon W, Burton ZF, Kashlev M.

Methods. 2009 Aug;48(4):333-45. doi: 10.1016/j.ymeth.2009.04.008. Epub 2009 May 4.

15.

Differential blocking effects of the acetaldehyde-derived DNA lesion N2-ethyl-2'-deoxyguanosine on transcription by multisubunit and single subunit RNA polymerases.

Cheng TF, Hu X, Gnatt A, Brooks PJ.

J Biol Chem. 2008 Oct 10;283(41):27820-8. doi: 10.1074/jbc.M804086200. Epub 2008 Jul 31.

16.

Functions of Saccharomyces cerevisiae TFIIF during transcription start site utilization.

Khaperskyy DA, Ammerman ML, Majovski RC, Ponticelli AS.

Mol Cell Biol. 2008 Jun;28(11):3757-66. doi: 10.1128/MCB.02272-07. Epub 2008 Mar 24.

17.

Genomic location of the human RNA polymerase II general machinery: evidence for a role of TFIIF and Rpb7 at both early and late stages of transcription.

Cojocaru M, Jeronimo C, Forget D, Bouchard A, Bergeron D, Côte P, Poirier GG, Greenblatt J, Coulombe B.

Biochem J. 2008 Jan 1;409(1):139-47.

18.

Genetic interactions between TFIIF and TFIIS.

Fish RN, Ammerman ML, Davie JK, Lu BF, Pham C, Howe L, Ponticelli AS, Kane CM.

Genetics. 2006 Aug;173(4):1871-84. Epub 2006 Apr 30.

19.

Direct observation of base-pair stepping by RNA polymerase.

Abbondanzieri EA, Greenleaf WJ, Shaevitz JW, Landick R, Block SM.

Nature. 2005 Nov 24;438(7067):460-5. Epub 2005 Nov 13.

20.

The highly conserved glutamic acid 791 of Rpb2 is involved in the binding of NTP and Mg(B) in the active center of human RNA polymerase II.

Langelier MF, Baali D, Trinh V, Greenblatt J, Archambault J, Coulombe B.

Nucleic Acids Res. 2005 May 10;33(8):2629-39. Print 2005.

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