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Results: 1 to 20 of 148

1.

A High-Content RNAi Screen Identifies Ubiquitin Modifiers That Regulate TNF-Dependent Nuclear Accumulation of NF-κB.

Fraser B, Maranchuk RA, Foley E.

Front Immunol. 2014 Jul 14;5:322. doi: 10.3389/fimmu.2014.00322. eCollection 2014.

PMID:
25071782
[PubMed]
Free PMC Article
2.

HIV-1 Vpr stimulates NF-κB and AP-1 signaling by activating TAK1.

Liu R, Lin Y, Jia R, Geng Y, Liang C, Tan J, Qiao W.

Retrovirology. 2014 Jun 9;11:45. doi: 10.1186/1742-4690-11-45.

PMID:
24912525
[PubMed - in process]
Free PMC Article
3.

Activated macrophage survival is coordinated by TAK1 binding proteins.

Mihaly SR, Morioka S, Ninomiya-Tsuji J, Takaesu G.

PLoS One. 2014 Apr 15;9(4):e94982. doi: 10.1371/journal.pone.0094982. eCollection 2014.

PMID:
24736749
[PubMed - in process]
Free PMC Article
4.

Loss of Trabid, a new negative regulator of the drosophila immune-deficiency pathway at the level of TAK1, reduces life span.

Fernando MD, Kounatidis I, Ligoxygakis P.

PLoS Genet. 2014 Feb 20;10(2):e1004117. doi: 10.1371/journal.pgen.1004117. eCollection 2014 Feb.

PMID:
24586180
[PubMed - in process]
Free PMC Article
5.

TAK1 binding protein 2 is essential for liver protection from stressors.

Ikeda Y, Morioka S, Matsumoto K, Ninomiya-Tsuji J.

PLoS One. 2014 Feb 3;9(2):e88037. doi: 10.1371/journal.pone.0088037. eCollection 2014.

PMID:
24498425
[PubMed - in process]
Free PMC Article
6.

TRAF6-mediated ubiquitination of NEMO requires p62/sequestosome-1.

Zotti T, Scudiero I, Settembre P, Ferravante A, Mazzone P, D'Andrea L, Reale C, Vito P, Stilo R.

Mol Immunol. 2014 Mar;58(1):27-31. doi: 10.1016/j.molimm.2013.10.015. Epub 2013 Nov 20.

PMID:
24270048
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

The TNF family member 4-1BBL sustains inflammation by interacting with TLR signaling components during late-phase activation.

Ma J, Bang BR, Lu J, Eun SY, Otsuka M, Croft M, Tobias P, Han J, Takeuchi O, Akira S, Karin M, Yagita H, Kang YJ.

Sci Signal. 2013 Oct 1;6(295):ra87. doi: 10.1126/scisignal.2004431.

PMID:
24084649
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Ubiquitination-induced fluorescence complementation (UiFC) for detection of K48 ubiquitin chains in vitro and in live cells.

Chen Z, Zhong Y, Wang Y, Xu S, Liu Z, Baskakov IV, Monteiro MJ, Karbowski M, Shen Y, Fang S.

PLoS One. 2013 Sep 5;8(9):e73482. doi: 10.1371/journal.pone.0073482. eCollection 2013. Erratum in: PLoS One. 2013;8(9). doi:10.1371/annotation/65881dc3-5bce-4f0b-9060-7079e16b1877.

PMID:
24039955
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Involvement of A20 in the molecular switch that activates the non-canonical NF-кB pathway.

Yamaguchi N, Oyama M, Kozuka-Hata H, Inoue J.

Sci Rep. 2013;3:2568. doi: 10.1038/srep02568.

PMID:
24008839
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Activation of the canonical IKK complex by K63/M1-linked hybrid ubiquitin chains.

Emmerich CH, Ordureau A, Strickson S, Arthur JS, Pedrioli PG, Komander D, Cohen P.

Proc Natl Acad Sci U S A. 2013 Sep 17;110(38):15247-52. doi: 10.1073/pnas.1314715110. Epub 2013 Aug 28.

PMID:
23986494
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

USP18 inhibits NF-κB and NFAT activation during Th17 differentiation by deubiquitinating the TAK1-TAB1 complex.

Liu X, Li H, Zhong B, Blonska M, Gorjestani S, Yan M, Tian Q, Zhang DE, Lin X, Dong C.

J Exp Med. 2013 Jul 29;210(8):1575-90. doi: 10.1084/jem.20122327. Epub 2013 Jul 1.

PMID:
23825189
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

EGLN3 inhibition of NF-κB is mediated by prolyl hydroxylase-independent inhibition of IκB kinase γ ubiquitination.

Fu J, Taubman MB.

Mol Cell Biol. 2013 Aug;33(15):3050-61. doi: 10.1128/MCB.00273-13. Epub 2013 Jun 3.

PMID:
23732909
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Helicobacter pylori activates NF-κB by inducing Ubc13-mediated ubiquitination of lysine 158 of TAK1.

Lamb A, Chen J, Blanke SR, Chen LF.

J Cell Biochem. 2013 Oct;114(10):2284-92. doi: 10.1002/jcb.24573.

PMID:
23606331
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Molecular basis of NF-κB signaling.

Napetschnig J, Wu H.

Annu Rev Biophys. 2013;42:443-68. doi: 10.1146/annurev-biophys-083012-130338. Epub 2013 Mar 11. Review.

PMID:
23495970
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Ras protein/cAMP-dependent protein kinase signaling is negatively regulated by a deubiquitinating enzyme, Ubp3, in yeast.

Li Y, Wang Y.

J Biol Chem. 2013 Apr 19;288(16):11358-65. doi: 10.1074/jbc.M112.449751. Epub 2013 Mar 8.

PMID:
23476013
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

miR-155 regulates immune modulatory properties of mesenchymal stem cells by targeting TAK1-binding protein 2.

Xu C, Ren G, Cao G, Chen Q, Shou P, Zheng C, Du L, Han X, Jiang M, Yang Q, Lin L, Wang G, Yu P, Zhang X, Cao W, Brewer G, Wang Y, Shi Y.

J Biol Chem. 2013 Apr 19;288(16):11074-9. doi: 10.1074/jbc.M112.414862. Epub 2013 Feb 28.

PMID:
23449975
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

The anti-inflammatory drug BAY 11-7082 suppresses the MyD88-dependent signalling network by targeting the ubiquitin system.

Strickson S, Campbell DG, Emmerich CH, Knebel A, Plater L, Ritorto MS, Shpiro N, Cohen P.

Biochem J. 2013 May 1;451(3):427-37. doi: 10.1042/BJ20121651.

PMID:
23441730
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

miR-486 sustains NF-κB activity by disrupting multiple NF-κB-negative feedback loops.

Song L, Lin C, Gong H, Wang C, Liu L, Wu J, Tao S, Hu B, Cheng SY, Li M, Li J.

Cell Res. 2013 Feb;23(2):274-89. doi: 10.1038/cr.2012.174. Epub 2012 Dec 18.

PMID:
23247627
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

TAK1 (MAP3K7) signaling regulates hematopoietic stem cells through TNF-dependent and -independent mechanisms.

Takaesu G, Inagaki M, Takubo K, Mishina Y, Hess PR, Dean GA, Yoshimura A, Matsumoto K, Suda T, Ninomiya-Tsuji J.

PLoS One. 2012;7(11):e51073. doi: 10.1371/journal.pone.0051073. Epub 2012 Nov 30.

PMID:
23226465
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

When ubiquitin meets NF-κB: a trove for anti-cancer drug development.

Wu ZH, Shi Y.

Curr Pharm Des. 2013;19(18):3263-75. Review.

PMID:
23151140
[PubMed - indexed for MEDLINE]
Free PMC Article

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